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Our full interview with Deborah Evans. We spoke to Deborah Evans about GLP-1 receptor agonists – the fat jabs – and what we have learned over the past 12-18 months. Read, watch and listen here - https://medicalupdateonline.com/2025/03/glp-1-ras-where-are-we-now-what-have-we-learned/?utm_source=youtube&utm_medium=social&utm_campaign=organic Register on our website for news straight to your inbox - https://medicalupdateonline.com/register/ This episode of ‘In Discussion With’ is also on Spotify. Listen to the full podcast now - https://creators.spotify.com/pod/show/medicalupdateonline/episodes/GLP-1-RAs--where-are-we-now--What-have-we-learned-e300s0f 0:00 - Introduction, titles & roles 1:24 - Are GLP-1 RAs easy & safe for weight loss? 3:08 - Differences - semaglutide vs. tirzepatide 6:31 - Side-effects of GLP-1 RAs 8:33 - Serious side-effects of GLP-1 RAs 10:07 - How to get GLP-1 RAs 12:27 - GLP-1 RAs via the NHS 14:54 - Additional support for patients 16:03 - Incorrect GLP-1 RA prescribing 18:02 - Counterfeit GLP-1 RAs 19:37 - Short-term use of GLP-1 RAs? 24:06 - Should you take GLP-1 RAs for life? 25:12 - Risks of sarcopaenia and osteoporosis 28:19 - Dose optimisation 30:34 - Tolerability variations 31:24 - Dose individualisation 33:20 - GLP-1 RA drug switching 35:58 - GLP-1 RA non-responders 37:24 - Starting GLP-1 RAs – what to expect 40:02 - Do we eat too much? 42:39 - Value of GLP-1 RA weight loss 43:56 - Possible anaesthetic risk 46:49 - Outro This interview was recorded on 06/02/2025. ___ Keep up to date with us across our network; Email us at - [email protected] Site - https://medicalupdateonline.com/ Twitter - https://twitter.com/medupdateon1ine Instagram - https://www.instagram.com/medicalupdateonline Facebook - https://www.facebook.com/medupdateonline LinkedIn - https://www.linkedin.com/company/medicalupdateonline This content is for informational purposes only, and does not replace the advice of your own doctor or healthcare professional. Copyright © 2022 MedicalUpdateOnline. IMI (a trading name of ICR UK Limited) is a digital communications agency that specialises in the pharmaceutical and medical industries. IMI was founded in 2003 by the current CEO Peter Mas-Mollinedo, a pharmacist and forward-thinking entrepreneur. IMI’s primary activities include the production of medical educational journals and bulletins, medical conference coverage and video interviewing of health care professionals worldwide to disseminate information such as trial results, new products, research, drug approvals, new accreditations, etc. It is a trusted provider of medical information to its extensive database of medical health care professionals in the UK, Europe and beyond. To find out more about IMI, please see our websites www.medicalupdateonline.com and www.medicalimi.com. Alternatively, you can email us at [email protected].

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Scientific knowledge of the gut microbiome has increased exponentially over the last decade. Recently, several studies have suggested that specific strains of bacteria, including Akkermansia muciniphila, are key to supporting the environmental conditions required for other related bacterial strains that facilitate healthy metabolic health. In this video, Colleen Cutcliffe, PhD, co-founder and CEO of Pendulum discusses groundbreaking research around Akkermansia mucinophila, the role of short-chain fatty acids (SCFAs) in stimulating GLP-1 pathways, implications for diabetes management, and how gut bacteria influence inflammation, gut integrity, and overall metabolic health. They also explore how diet, antibiotics, and stress impact the microbiome, potential roles of probiotics in inflammatory bowel disease (IBD), pediatric gut health, and exciting emerging research on the gut-brain axis and neurological conditions like Parkinson's disease. Colleen highlights Pendulum's rigorous scientific approach, including clinical trials and innovative manufacturing practices that ensure product viability and effectiveness. Promotional code STERLING20 can be applied for 20% off of first membership purchases (https://pendulumlife.com). Please note that Dr. Sterling has no financial affiliation with Pendulum. This code is provided only as a discount to listeners and does not constitute a clinical recommendation or medical advice. Chapters: - 00:00 Intro: Gut Microbiome Essentials - 02:03 Pendulum's Biotech Innovation - 06:15 GLP-1 & Metabolic Health - 09:59 Probiotic Industry Insights - 17:17 Importance of Akkermansia - 24:17 Clinical Results for Diabetes - 29:28 Manufacturing Challenges - 39:13 Diet's Impact on Microbiome - 43:35 Gut-Brain Connection - 46:50 Next Steps & Resources Spotify Channel: https://podcasters.spotify.com/pod/show/sterlingmdphd/ Social & Website: Instagram - https://www.instagram.com/sterlingmdphd X - https://x.com/sterlingmdphd Facebook - / sterlingmdphd Newsletter - http://eepurl.com/hQpdqT Apple Podcasts: https://apple.co/3y438C9 References & Show Notes: http://www.nicksterling.com/ This content is not medical advice, is for general information purposes only, and does not constitute the practice of medicine or any other healthcare professional services. No doctor-patient relationship is formed. This content is not a substitute for medical evaluation or treatment and does not take precedence over information provided to you by your healthcare provider or official public health sources. Please visit http://nicksterling.com/terms for full Terms of Use.

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Mama June Excels, Shocks With Almost 100-Lb. Weight Loss: A Transformative Journey Mama June Shannon, the reality TV star from the popular shows Here Comes Honey Boo Boo and Mama June: From Not to Hot, has stunned fans and critics alike with her incredible weight loss transformation. Known for her candid personality and turbulent life, Mama June’s nearly 100-pound weight loss is a testament to her determination to regain control of her health and personal life. A Journey to Health and Wellness Over the years, Mama June has been open about her struggles with weight management, addiction, and personal issues. In 2016, she underwent gastric sleeve surgery, a life-changing decision that helped her lose over 300 pounds initially. However, like many who undergo weight loss surgery, maintaining the weight loss proved to be a challenge, as life stressors often got in the way of consistent health practices. Recently, Mama June decided to recommit herself to her health goals. Over a period of several months, she has shed almost 100 pounds, thanks to a combination of diet, exercise, and medical interventions. Using a new weight loss medication called tirzepatide (similar to the popular drug Mounjaro), she has seen rapid yet sustainable progress, reportedly losing up to 4-5 pounds per week. In addition to the medication, Mama June has adopted a strict workout regimen, hitting the gym three to four times a week, and follows a disciplined diet plan, resisting temptations despite being surrounded by family who enjoy indulgent meals. Motivations Behind the Transformation In interviews, Mama June has shared that her transformation is not just about appearances but about reclaiming her health and setting an example for her family. With a goal of reaching 170-180 pounds, she has about 70 pounds left to lose but remains focused on the journey rather than the destination. Mama June’s weight loss is not just about numbers on the scale. Her transformation is deeply tied to her journey toward sobriety and mental health. She has faced public scrutiny for her past struggles with addiction, which strained her relationships with her daughters and her husband, Justin Stroud. Despite these challenges, Mama June is determined to show that personal growth is possible, even in the face of adversity.

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Finally opening up and sharing about my recent weight loss journey. This has been a silent battle but I'm honored to share my truth with you all today. As always, be sure to like, drop a comment & subscribe! Appreciate you, value you...yea you bad W A T C H T H E S E T O O: going to a nutritionist vlog: https://youtu.be/bUkWchW7ekg 2025 reset: https://youtu.be/Hs3YVWa9W0o P R O D U C T S M E N T I O N E D: Eat right for life book: https://amzn.to/4gIKgg6 C O N N E C T W I T H M E : Community Tip Jar + My Other Internet Homes: https://linktr.ee/lifeofrehc My Amazon Storefront! : https://amzn.to/3U3Wx3B My ShopMy Storefront: https://shopmy.us/lifeofrehc My Digital Products: https://lifeofrehc.etsy.com B U S I N E S S / C O L L A B S: Please e-mail [email protected] M Y Y O U T U B E E Q U I P M E N T - Sony ZV-1: https://bit.ly/3HKUEBx - Vlogger Kit Bundle (what I got) : https://bit.ly/3Ci0PMr - Sony Vlogger Accessory Kit: https://bit.ly/35OAhpR - Sandisk Extreme PRO 128GB SD Memory Card: https://bit.ly/3sIxnvO - Ring Light: https://bit.ly/3akVI17 - I use Thematic for my copyright free music: https://app.hellothematic.com/?via=rena - I use Tubebuddy to help optimize my videos for Youtube growth: https://www.tubebuddy.com/lifeofrehc M Y P R O D U C T S : - The Do Better Budget: - https://lifeofrehc.com/product/do-better-budget/ C O U P O N C O D E S: ~ Try Banish acne clearing skincare products! : https://bit.ly/3S0kGHd [Discount Code: RENA] ~ Use my code "RENA505 " to get % off your next order at passionplanner.com (https://passionplanner.rfrl.co/e81nj) ~ Use my code "LIFEOFREHC" to get % off your next order at The Lip Bar (www.thelipbar.com) ~ Use my affiliate link to save on Merit Beauty: https://muse.meritbeauty.com/rena ~ Use my Rakuten code to sign up and get $10: https://www.rakuten.com/r/RENAMO31 A B O U T M E: I'm a 29 year old CPA/content creator sharing life from start to finish. These 20 somethings are a lot so there's always something going on. It's best to just stick around. :) M Y O T H E R I N T E R N E T H O M E S ! - Blog 💻: https://www.lifeofrehc.com - IG 📸: https://www.instagram.com/lifeofrehc - Pinterest📍: https://www.pinterest.com/lifeofrehc - Like it to Know it: https://www.liketoknow.it/lifeofrehc - Tik Tok: @lifeofrehc M U S I C DISCLAIMER: Links included in this description might be affiliate links. If you purchase a product or service with the links that I provide I may receive a small commission. There is no additional charge to you! Thank you for supporting my channel! #weightlossjourney #weightloss #howilostweight

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The Truth About GLP-1 Micro dosing: A Reaction to Dr. Tyna's Episode In this episode of The Downsized, hosts Christopher Durham and Laraine Durham react to Dr. Tyna's controversial video titled 'The GLP-1 Micro dosing Lie: It's Not a Weight Loss Strategy.' The episode delves into Dr. Tyna Moore's original intentions for GLP-1 micro dosing, which was not meant for weight loss but rather for those who are metabolically healthy. Christopher and Laraine, both experienced users of GLP-1 medications like Ozempic, Wegovy, Tirzepatide, Mounjaro, and Zepbound, share their insights on the misuse and commercialization of GLP-1 microdosing in today's health industry. They emphasize that micro dosing involves using a tiny fraction (one-fifth to one-tenth) of the standard starting dose and is aimed at addressing issues like inflammation, autoimmune diseases, and brain fog. The hosts also critique the misinformation spread by telemedicine companies and influencers who market standard starting doses as micro doses. The episode calls for greater transparency and credible information to guide those using GLP-1s for obesity treatment. Throughout the discussion, Christopher and Laraine share personal experiences and stress the importance of consulting healthcare professionals for personalized treatment plans. They also express their openness to furthering the conversation with Dr. Tyna. The episode aims to bring clarity and real-world insights into the complex topic of GLP-1 micro dosing. WATCH DR TYNA'S VIDEO: https://www.youtube.com/watch?v=Ll3SORezgFY&t=529s DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store As an Amazon Associate, I earn from qualifying purchases. DOWNSIZED WEBSITE: https://thedownsized.org/ BOOK THE DOWNSIZED AT SEA CRUISE 2026: https://thedownsized.org/downsized-at-sea-2026/ 00:00 Introduction to GLP-1 Microdosing Debate 00:15 Christopher and Laraine 01:35 Reacting to Dr. Tyna's Controversial Take 01:46 Who is Dr. Tyna? 02:55 Dr. Tyna's Perspective on Microdosing 04:19 Microdosing Misconceptions and Misuse 10:28 The Science and Reality of Microdosing 19:34 Addressing the Stigma and Scams 28:38 Final Thoughts and Invitation to Dr. Tyna 31:23 Conclusion and Viewer Support

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In this video, we dive into the quiet shift in Meghan Trainor’s message following her weight loss, and the heartbreaking moment Lizzo vandalized her own album cover — admitting she no longer sees herself as beautiful. What do these two stories reveal about the state of body positivity in 2025? Is self-love being sold back to us as a trend? And what happens when the very people who were told to love themselves start to believe they’re not enough? Watch, comment, and let’s have a real conversation. Do you think body positivity still means something — or has it become just another commercial trend? Would love to hear your thoughts. Let’s talk in the replies.

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