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UPDATE TO THIS VIDEO in 2023: I'm glad to say that many of the commenters were right, I love glycine and use 3g before bed now nearly every night. I highly suggest using it if you're not eating meat off the bone, skin (pork rinds), eating gelatin, bone broths, or finding other connective tissue. IMHO, unless you're in keto for medical reasons and need to stay at therapeutic levels, the blood sugar bump from a few grams of glycine before bed is worth the improved sleep. Definitely still don't think it should have been in a product marketed towards keto though. https://blog.priceplow.com/keto-supplements Was GLYCINE to blame when BPI Sports "Keto Aminos" spiked Mike's blood sugar and dropped his ketone levels??? The answer is partially YES. This is the first of many single amino acid reviews, and this one actually TASTES a bit like sugar. It's glucogenic, meaning it induces gluconeogenesis (ie "MAKES NEW SUGAR"). AVERAGES - Blood Sugar: +12 - Blood Ketones: -0.1667mmol/L Day 1: - Fasted Blood Sugar Pre: 84 - Ketones Pre: 0.7 - Blood Sugar 45 minutes post (no training or eating): 102 - Ketones Post:0.4 Day 2 (next day): - Fasted Blood Sugar Pre: 90 - Ketones Pre: 0.4 - Blood Sugar 45 minutes post (no training or eating): 89 - Ketones Post: 0.4 Day 3: - Fasted Blood Sugar: 78 - Ketones Pre: 0.6 - Blood Sugar 45 minutes post (no training or eating): 97 - Ketones Post: 0.4 It is appalling that anybody would put this into a supplement that is marketed towards Keto Dieters. See Mike's BPI Keto Aminos review here: https://www.youtube.com/watch?v=OyKr88ZXmIs BPI SPORTS: REFORMULATE YOUR KETO AMINOS NOW. Thanks to NutraBio for the 3rd Party Lab-Tested Tub: https://www.priceplow.com/nutrabio/glycine?ic=5 This Lot's Lab Test: https://checkmysupps.com/225045.pdf What is Amino Acid Spiking? https://blog.priceplow.com/protein-scam-amino-acid-spiking Glycine is anabolic (err, anti-catabolic) in rats?? Maybe: https://www.ncbi.nlm.nih.gov/pubmed/27094036 Keep following my Keto Supplement Tests: https://blog.priceplow.com/keto-supplements Save with PRICEPLOW on BPI Sports: https://www.priceplow.com/bpi-sports?ic=5 https://www.priceplow.com/glycine?ic=5 SUPPLEMENT DEALS: https://www.priceplow.com/deals?ic=5 Follow us on Social Media! FACEBOOK: https://www.facebook.com/PricePlow INSTAGRAM: https://www.instagram.com/PricePlow/ TWITTER: https://twitter.com/PricePlow BLOG: https://blog.priceplow.com

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Patient in this case is @East-Bound (check out his YouTube Channel!) @chubbyemu video of this case: https://www.youtube.com/watch?v=ChPeG19qKUo Christopher's recount of his case: https://www.youtube.com/watch?v=7BpymtR2vpA Audio podcast for Heme Review: https://anchor.fm/chubbyemu Tweet me: https://www.twitter.com/hemereview IG me: https://www.instagram.com/hemereview FB me: https://www.facebook.com/hemereview Timestamps: 0:00 - Introduction 0:30 - Can you tell me about yourself? 1:21 - How did you get into lifting weights? 3:14 - Bernard talking about his high school experience 4:12 - What was your relationship like with the gym? 5:48 - How did things change in Christopher's life at the end of high school? 8:17 - Other people's perception of weight 9:24 - Christopher describing long time girlfriend cheating on him 10:32 - People judging others based on weight 14:45 - How did you get back in to fitness during college? 17:54 - Weight loss plateau 20:54 - Weight loss supplements 24:46 - Transition from supplements to harder weight loss chemicals 31:04 - What is clenbuterol like? 33:40 - How did you come across DNP? 35:41 - What is being on DNP like? 40:00 - How long did you take DNP for? 44:58 - What do you remember from day of accident? 50:19 - Tales from the emergency room, September 3 2015 51:10 - Waking up in the ICU 55:25 - How did the accident change your relationship with the gym? 57:54 - What would you tell someone thinking of taking DNP today? 2,4-Dinitrophenol (DNP) is a chemical that is not approved for weight loss. It is a classic case of efficacy, but without safety in the setting of weight loss. This setting of weight loss can be prone to chemical misuse, further exacerbating understanding in human systems. Christopher is one of 2 - 3 cases documented in literature to have survived an accident with DNP for weight loss. As of 2021, one organization has permission from the US FDA to investigate DNP in some neurodegenerative disorders. These are rare diseases with limited standards of care, therefore extenuating circumstances to find anything that could potentially improve patient outcomes. References: Role of dantrolene in dinitrophenol (DNP) : A continuing question? Am J Emerg Med. 2019 Jun;37(6):1216.e1-1216.e2. https://pubmed.ncbi.nlm.nih.gov/30948257/ 2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity . J Med Toxicol. 2011 Sep;7(3):205-12. https://pubmed.ncbi.nlm.nih.gov/21739343/ Ambient temperature and mortality from unintentional . JAMA. 1998 Jun 10;279(22):1795-800. https://pubmed.ncbi.nlm.nih.gov/9628710/ Beware the yellow slimming pill: fatal 2,4-dinitrophenol. BMJ Case Rep. 2016 Apr 4;2016. https://pubmed.ncbi.nlm.nih.gov/27045052/ Dantrolene is not the answer to 2,4-dinitrophenol poisoning: more heated debate. BMJ Case Rep. 2018 Dec 19;11(1):e225323. https://pubmed.ncbi.nlm.nih.gov/30573533/ The effect of 2,4-dinitrophenol on adipose-tissue metabolism. Biochem J. 1969 Feb;111(4):431-44. https://pubmed.ncbi.nlm.nih.gov/4388239/ The mechanism of uncoupling of oxidative phosphorylation by 2,4-dinitrophenol. J Biol Chem. 1967 Oct 25;242(20):4577-83. https://pubmed.ncbi.nlm.nih.gov/4964808/ MECHANISMS OF DINITROPHENOL TOXICITY. Simon E.W. Biological Reviews. Vol 28. (4). Nov 1953. Identification and Importance of Brown Adipose Tissue in Adult Humans. https://www.nejm.org/doi/full/10.1056/NEJMoa0810780 Mitochondrial uncoupling as a target for drug development for the treatment of obesity. Obes Rev. 2001 Nov;2(4):255-65. https://pubmed.ncbi.nlm.nih.gov/12119996/ LC-MS-MS analysis of 2,4-dinitrophenol and its phase I and II metabolites. J Ana Toxicol. Jan-Feb 2007;31(1):55-61. https://pubmed.ncbi.nlm.nih.gov/17389084/ Uncouplers of oxidative phosphorylation. Environ Health Perspect. 1990 Jul;87:213-8. https://pubmed.ncbi.nlm.nih.gov/2176586/ Texas Woman Charged with Selling Misbranded https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/press-releases/texas-woman-charged-selling-misbranded-drug

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