Transcript Does Insurance Typically Cover Semaglutide for Weight Loss Treatments?Oncotarget published this trending research paper on February 2, 2021, entitled, "Testosterone deficiency in men receiving immunotherapy for malignant melanoma" by researchers from the University of Iowa. Abstract: Immunotherapy has been established as a standard of care for patients with malignant melanoma, however, the long-term side-effects of immunotherapy are still emerging. Studies over the last decade have documented increasing reports of endocrine dysfunction following the initiation of immunotherapy. Our study aimed to detect the proportion of men who have low testosterone before, during, and or/after receiving immunotherapy for malignant melanoma, and to determine the proportion of men who receive testosterone replacement therapy after detection of low testosterone. We performed retrospective chart review of patients with malignant melanoma treated with immunotherapy. Low testosterone was identified in 34 out of 49 patients at some point during their treatment with immunotherapy. Despite low testosterone levels in two-thirds of patients, only three patients were treated with testosterone replacement therapy. In addition to laboratory evidence of low testosterone, patients were also symptomatic as 43 out of 49 patients reported fatigue to their providers. Four patients developed hypophysitis and subsequent hypopituitarism, all of whom were receiving Ipilimumab. We conclude that patients with stage 3 or 4 melanoma treated with immunotherapy appear to be at an increased risk of developing testosterone deficiency during their treatment. Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.27876 DOI - https://doi.org/10.18632/oncotarget.27876 Full text - https://www.oncotarget.com/article/27876/text/ Correspondence to - Madeline Peters - [email protected] Keywords - cancer, melanoma, immunotherapy, testosterone deficiency, androgens, skin cancer About Oncotarget Oncotarget is a bi-weekly, peer-reviewed, open access biomedical journal covering research on all aspects of oncology. To learn more about Oncotarget, please visit https://www.oncotarget.com or connect with: SoundCloud - https://soundcloud.com/oncotarget Facebook - https://www.facebook.com/Oncotarget/ Twitter - https://twitter.com/oncotarget YouTube - https://www.youtube.com/c/OncotargetYouTube/ LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Oncotarget is published by Impact Journals, LLC please visit https://www.ImpactJournals.com or connect with @ImpactJrnls Media Contact [email protected] 18009220957El Toro CBD Gummies for ED Reviews: Evaluating Their Effectiveness and User InsightsPerfect playlist for big guys in the gym 🎖️ 00:00 Rihanna - Only Girl 03:51 Clean Bandit - Rather Be 07:50 Lady Gaga - Applause 11:15 Rihanna - Umbrella 15:23 Kesha - TiK ToK 18:40 Katy Perry - Firework 22:25 Carly Rae Jepsen - Call Me Maybe 25:31 Clean Bandit - Symphony feat. 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Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. 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Nitric oxide helps relax blood vessels, allowing for increased blood flow to the penis during arousal. This can lead to stronger and longer-lasting erections, making sexual experiences more satisfying for both partners. Additionally, L-arginine has been shown to improve overall cardiovascular health, which is essential for sexual function. In addition to L-arginine, Dr. Oz ED Gummies also contain tribulus terrestris, a plant extract known for its potential aphrodisiac effects. Tribulus terrestris has been used for centuries in traditional medicine to enhance libido and improve sexual performance. By including this ingredient in the formula, Dr. Oz ED Gummies aim to boost sexual desire and pleasure, helping men regain their confidence in the bedroom. How Do Dr. Oz ED Gummies Work? The mechanism behind Dr. Oz ED Gummies’ effectiveness lies in their ability to improve blood circulation and optimize sexual function. By increasing nitric oxide levels in the body, the gummies help dilate blood vessels in the penis, allowing for more significant blood flow when aroused. This, in turn, leads to firmer and more sustainable erections, addressing one of the primary causes of erectile dysfunction. Furthermore, the combination of ingredients in Dr. Oz ED Gummies works synergistically to support overall sexual health and vitality. In addition to promoting better blood flow, the gummies help boost energy levels, reduce fatigue, and enhance stamina, all of which are essential for a satisfying sexual experience. By addressing multiple aspects of sexual function, Dr. Oz ED Gummies offer a comprehensive solution for men looking to improve their performance in the bedroom. Unlike prescription medications for ED, which can come with potential side effects and interactions, Dr. Oz ED Gummies are made from natural ingredients and are generally well-tolerated. 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