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In this presentation from CKD Update 2024, Dr. Satinath Mukhopadhyay explores the renal benefits of combining SGLT2 inhibitors and GLP-1 receptor agonists in patients with type 2 diabetes. He discusses the additive and possibly synergistic effects of this combination in improving renal outcomes, reducing eGFR decline, and enhancing cardiovascular and metabolic control. The session highlights key trials such as FLOW, and explains the underlying mechanisms of action, including inflammation reduction, fibrosis regulation, and improved sodium handling in the kidneys. Key points covered: * A case study showing renal improvement with SGLT2 inhibitors and GLP-1 receptor agonists * The FLOW trial outcomes and benefits of the combination therapy * The mechanisms of action, including effects on blood pressure, weight, and glycemic control * The importance of combination therapy in improving renal outcomes in type 2 diabetes * Proposals for optimal renal protection therapies in diabetic patients Dr. Mukhopadhyay also addresses the practical considerations of this therapy, including the potential challenges due to costs and coverage.

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🔥 Looking to Drop Some Weight Before Summer? 🔥 Summer is right around the corner, and if you want to shed some weight and feel your best, here’s your game plan: 1️⃣ Set Goals & Find Your WHY – Knowing your deeper reason will keep you motivated when things get tough. 2️⃣ Start Mornings with Strength Training – Muscle boosts metabolism, helping you burn more fat. 3️⃣ Incorporate Fasting & Eat More Protein – Give your body time to burn fat and fuel it with the right nutrients. 4️⃣ Drink More Water – Hydration is key for fat loss and energy. 5️⃣ Focus on Stress & Sleep – Poor sleep and high stress lead to cravings and fat storage. Start now, stay consistent, and see the results by summer! ☀️💪 What’s your biggest challenge when it comes to weight loss? Drop a comment! ⬇️\ Hi, I’m Coach Brad, a Christian fitness coach and the founder of Get You In Shape. Since 1998, I’ve been helping busy Christian men—especially CEOs, entrepreneurs, and professionals over 40—reclaim their health, lose weight, and transform their bodies with a Follow-the-Darn-Instructions plan and the accountability to stick with it. As a husband, father of seven, and business owner, I understand the struggle of balancing faith, family, and fitness. That’s why I created Transformed Temple—an online coaching program that goes beyond workouts and diets. My approach integrates faith, fitness, and mindset to help you honor God by taking care of your body so you can serve others, live with energy, and feel 10 years younger. Ready to start your journey? Visit https://www.GetYouInShape.com. Download your FREE 8 Hacks Guide to look & feel 10 years younger! https://www.getyouinshape.com/8-tips/ #ChristianFitness #WeightLossOver40 #MensHealth #fitnesscoach #weightlosscoach #ChristianMensHealth #MorningRoutineOver40 #BiblicalHabits #ChristianFitnessCoach #faithandfitness #onlinefitnesscoach #transformationCoach

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Adrian's Fat Loss System ➜ https://bit.ly/__CLICK__HERE ➜ Lose 30 Pounds (𝗼𝗳 𝗕𝗲𝗹𝗹𝘆 𝗙𝗮𝘁) EVERY 30 Days . . "Adrian, I 𝗟𝗼𝘀𝘁 𝟮𝟮 𝗣𝗼𝘂𝗻𝗱𝘀 𝗶𝗻 𝟮𝟯 𝗗𝗮𝘆𝘀. Why Haven't I Lost 30 By Now!?" -𝙽𝚊𝚘𝚖𝚒 𝚆𝚒𝚕𝚎𝚢 ➜ https://bit.ly/__CLICK__HERE ➜ Adrian's Fat Loss System . . More Bed Sheet Workouts https://www.youtube.com/watch?v=Zi03QQ5wThY https://www.youtube.com/watch?v=I7sl8peXZTU https://www.youtube.com/watch?v=gnIW-CA1O04 https://www.youtube.com/watch?v=2PGdiIEjAck https://www.youtube.com/watch?v=Q1IpApW3c7w TOO HARD: Use a towel, blanket or lighter sheet TOO EASY: Use a battle rope instead of bedsheets or do a battle rope workout at https://www.youtube.com/watch?v=cnzgu18l-14&list=PL5qWKDYV54nFqkssbgD5eYnvdF0_p67Gf to lose weight all over including your stubborn belly fat. Here is a quick overview of how this workout is laid out • Set 1 (ONE Round = 4 minutes) • Set 2 (TWO Rounds = 8 minutes) • Set 3 (THREE Rounds = 12 minutes) • 1-minute break between sets Each Round is... • 20 Sec. Bedsheet Shuffle • 20 Sec. Sprint • 20 Sec. Rest • 20 Sec. Bedsheet Hip Toss • 20 Sec. Burpee • 20 Sec. Rest • 20 Sec. Bedsheet Side-to-Side • 20 Sec. Squat & Kick • 20 Sec. Rest • 20 Sec. Bedsheet Shake • 20 Sec. Jumping Jack • 20 Sec. Rest & Begin Next Round So each time I say go in the video you will be doing 20 seconds of a bed sheet variation exercise followed by either sprints, jumping jacks, squat and kicks or burpees. My form is not perfect for all of the exercises and yours probably will not be perfect either but the point is for you to go as fast as you can be trying to wear yourself out to burn the most fat you possibly can. Truth about losing belly fat When you lose weight you lose weight all over your body along with some belly fat but even when you lose a huge amount of weight like you will with this bedsheet workout you will see you will still have some belly fat left over and for everyone there last 5-to-15 pounds is mostly located in their belly area with women have their last bits of fat on their belly and hips. So do not be discouraged is you still have some (not a lot of) belly fat left after losing 20 or more pounds. Your last bit of stubborn belly fat can be gotten rid of with a plan to lose your last 10 pounds which is usually just your belly fat with a plan like this one at http://www.nowloss.com/weight-loss-plan-to-lose-your-last-10-pounds.htm REMEMBER: you can’t target belly fat or just say I’m only going to lose stomach fat because unlike toning where you can target areas of your body, weight loss is a whole body endeavor where you gradually lose fat all over at in different places at different times with your stomach fat most usually being the last bit to go. If you have a bedsheet there is no excuse for you not to do this work out or at least give it an honest try. For the best results it is best you do this workout at least 3-to-4 days per week 1-to-2 times per day to lose belly fat as fast as possible.