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Is LDL cholesterol the best way to measure and predict heart disease? New research suggests no! Dave Feldman is an engineer turned citizen scientist who has devoted his life to understanding a phenomenon that some individuals around the world are experiencing: a robust increase in LDL cholesterol while on a ketogenic diet. Dave’s past research has identified a unique phenotype dubbed Lean Mass Hyper-Responders (LMHRs). LMHRs respond to ketogenic therapy with a metabolic profile that includes elevated LDL-C and ApoB levels with otherwise healthy metabolic markers, including low triglycerides, high HDL, low blood pressure, low insulin resistance, and low BMI. In Dave’s most recent publication, what most doctors would consider dangerously high LDL levels in LMHRs did not correlate with an increased risk of heart disease. In this video, Dr. Bret Scher sits down with Dave Feldman to discuss this groundbreaking study and its implications for ketogenic therapy and cardiology. *Key Takeaways:* - LMHRs on a long-term ketogenic diet who show elevated LDL can show robust metabolic health - LDL-C and ApoB were not linked to plaque progression in LMHRs - Existing plaque did predict future plaque accumulation in LMHRs - Individualized approaches to cardiovascular risk assessment are crucial to serve this group better. 🎬 These exciting new findings are featured in Dave Feldman and Jen Isenhart’s  upcoming documentary, *The Cholesterol Code,* the story of how one engineer’s health experiment sparks a global investigation, exposing myths about cholesterol and reshaping our understanding of heart health. Real stories of healing from disease with ketogenic diets provide a blueprint for using food as powerful medicine. Visit [cholesterolcodemovie.com](https://cholesterolcodemovie.com/) to learn more about the film and to be the first to hear about private screenings and the general release in the fall. *Expert Featured:* Dave Feldman CEO, Citizen Science Foundation https://x.com/realDaveFeldman Cholesterol Code website: https://cholesterolcode.com/ *Resources Mentioned:* Coronary Artery Plaque Progression in Asymptomatic Lean Mass Hyper-Responders: A Case Series - https://www.jacc.org/doi/10.1016/j.jacadv.2025.101686 *CMEs Mentioned:* _Managing Major Mental Illness with Dietary Change: The New Science of Hope_ - https://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616 _Brain Energy: The Metabolic Theory of Mental Illness_ - https://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ *About us:* Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. *Timestamps:* 0:00 - Introduction to Lean Mass Hyper Responders and researcher Dave Feldman. 3:10 - What is the background and setup of Dave’s new Lean Mass Hyper Responder (LMHR) trial? What did the participants’ baseline data look like? 8:00 - What did the 1 year follow up scans show for the participants? Did their elevated LDL & ApoB lead to an increase in plaque buildup? What is the difference between LDL & ApoB? 21:42 - Did the group see an increase in plaque volume and was it rapid? Did anyone see a decrease? What does predict a future increase in plaque if not LDL or ApoB? 26:48 - What causes arterial plaque and what doesn’t cause it? 29:45 - Will Dave Feldman’s study help clinicians and patients accept or continue ketogenic therapy when LDL may be high? 33:09 - What are the limitations to the study and the interpretations to the study? 39:10 - What does Dave Feldman hope a cardiovascular researcher would take away from this study? How does Dave feel about potential pushback from the medical community? 43:45 - Where can people hear more from Dave Feldman and follow his work?

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The ketogenic diet, more commonly known as the keto diet, has been gaining traction in the health and wellness scene in recent years. In fact, the diet has skyrocketed in popularity as more and more people are turning to this food plan for rapid weight loss, heightened energy, and improved overall health. As millions of people around the world infuse their lives with the benefits of the keto diet, they’re also discovering the practicality and effectiveness of the various keto supplements that can help them maintain a state of ketosis for longer periods. One of the keto supplement stores benefiting from keto diet’s surging popularity is ketosupplements.com. Recently, this productstein founded on the premise that millions of people are actively searching online for the best keto supplements. Filling this need was a no-brainer. One of the most popular reality television series airing nowadays is called Shark Tank. This hit TV show’s premise features a panel of successful entrepreneurs and investors who mentor, invest in, and bring to market new and novel products. But this show has also become an arena for launching a number of successful keto supplements.

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One of the most successful keto products that was featured on Shark Tank, and got investment from several Sharks, is called Keto Trim, an appetite suppressant and weight loss supplement that supports ketosis, helping you to burn more fat in a shorter amount of time. With the popularity of the Shark Tank, this product has also become very popular in the keto community, and many have purchased it with amazing results.

Another is Keto Fuel, a meal replacement shake developed for the ketogenic lifestyle, which appeared on Shark Tank, garnering an even bigger Shark Tank deal with one of the sharks. The product made a splash in the ketogenic community, hitting #1 sales rank and becoming a standard in the keto diet for many when they want and need to indulge their sweet tooth.

Said to be the most cutting edge keto supplement from Shark Tank to hit the market, it is the brain-optimising supplement that helps boost mental clarity and focus. Keto Boost caught the eye of the Sharks with its scientific research while transforming the brain into pure gold. The founders managed to impress the Sharks with their unique formula. This product can optimise cognitive functioning while keto dieters remain on low-carb, high-fat diet.

What to Look for in a Keto Supplement

When searching online for a keto supplement, you want to find a product that is supported by scientific research, and a product that contains quality ingredients from natural sources (such as exogenous ketones, MCT oil and other natural substances), that will help you stay in ketosis and burn fat. Also, look at the reviews provided by other purchasers of the product, and ask your physician for advice as adding a new keto supplement to your daily routine should be done carefully.

Another important consideration when choosing a keto supplement is dosage and serving size. Be sure to read the supplement label carefully to determine whether you’re taking the product at the correct dosage, which can vary from brand to brand. Also, some supplements aren’t intended for continuous use but rather with a loading phase or adjustment period in mind. Be sure to stick with the product and its dosage instructions for the appropriate period of time to ensure you reap the most benefits.

It’s also worth factoring in the total purchasing price of the supplement and comparing it to that of other products. Although price shouldn’t be the most significant element in your decision making process, you want to feel that you’re getting quality for your hard-earned value. Bundle, discount, and sale offers can all help you to reduce the cost of your favorite keto supplements.

Common Questions About Keto Supplements on Shark Tank

1. Are keto supplements safe to use?

Yes, when taken as recommended and in combination with a healthy diet and lifestyle, keto supplements can be safe and effective in promoting weight loss and health. Make sure to consult your health practitioner prior to adding any new supplement to your daily routine, as it might be dangerous for you.

2. Do keto supplements have any side effects?

Once you’ve moved past the acclimation period, certain individuals can expect mild side effects, such as digestive issues or headaches. These unpleasantries are short-lived and, for the most part, can be avoided by starting with a smaller dose and gradually increasing it over time. Stop taking the supplement if you experience severe side effects and talk to a medical provider.

3. How long does it take to see results from keto supplements?

the timeline doesn’t differ much since it’s variable from when it comes to the human body, but you might notice a change of regaining your energy, weight and even your clear mentality within these few days of when you first started taking a keto supplement, while you could have results of long term use showing to your body sooner than later if you’re not so consistent with the use of the supplement.

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BioKeto Gummies contain a powerful blend of ingredients that are designed to help your body enter ketosis quickly and easily. By providing your body with the essential nutrients it needs to produce ketones, these gummies can help you switch from burning carbs for energy to burning fat instead. This can lead to rapid weight loss and increased energy levels, making it easier to stick to your diet and exercise routine.

One of the key ingredients in BioKeto Gummies is beta-hydroxybutyrate (BHB), which is a type of ketone that is produced by the liver during ketosis. By supplementing with BHB, you can help your body produce more ketones and enter ketosis faster. This can help you burn fat more efficiently and lose weight more quickly than with diet and exercise alone.

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