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Learn about the design of a trail-blazing Randomized Controlled Trial (RCT) that will explore the physiology and biology of brain energy metabolism, while also informing clinical applications of ketogenic therapy as an adjunctive treatment option for patients with bipolar and schizophrenia spectrum disorders. RCTs are considered the gold standard when looking at the efficacy and safety of new treatment options. This type of research is necessary to understand whether ketogenic therapy should be offered as a first-line treatment option, as well as what types of strategies could increase accessibility of this intervention in the future. Dr. Bret Scher interviews principal investigators Dost Öngür, MD, PhD, and Dr. Virginie-Anne Chouinard, MD, about the details of this trial at McLean Hospital, a top-rated, Harvard-affiliated psychiatric hospital. Learn more about the impressive design of this trial which includes a multidisciplinary approach to clinical care, gathering a variety of data to inform understanding of underlying brain energy mechanisms (including MRIs and metabolic markers), and an “open-label” approach that will allow the control group to opt into ketogenic therapy at the end of the first trial phase if desired. Dr. Dost Öngür William P. and Henry B. Test Professor of Psychiatry, Chief of the Division of Psychotic Disorders, & Director of the Schizophrenia and Bipolar Disorder Research Program at McLean Hospital https://www.mcleanhospital.org/profile/dost-ongur Dr. Virginie-Anne Chouinard, Staff psychiatrist and Director of Research at McLean OnTrack™ & Instructor in Psychiatry at Harvard Medical School. https://www.mcleanhospital.org/profile/virginie-anne-chouinard Press release about the trial: https://www.prnewswire.com/news-releases/mclean-hospital-launches-clinical-trial-of-ketogenic-therapy-for-bipolar-disorder-302062402.html For information on enrolling: https://clinicaltrials.gov/study/NCT06221852 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. Timestamps 0:00 Introduction 2:03 Interest leading up to a keto for bipolar study 5:36 Brain energy metabolism and bipolar 7:44 Patient population for the new Harvard study 8:46 About the study 9:21 Dietary studies vs pharmacologic studies 11:55 The different interventions in the keto for bipolar study 14:42 What researchers will be looking at during the clinical trial 17:20 Balancing mechanism and clinical impact in research 19:21 Impact of the clinical trial 21:54 Working with a clinician for ketogenic therapy 25:30 Conclusion #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #BipolarDisorder #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis #MentalIllness #AlternativeTreatment #Obesity #MedicationSideEffects #Schizophrenia #SchizoaffectiveDisorder #SchizophreniaSpectrumDisorders

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Wondering how to lose weight during menopause? Or what causes menopausal weight gain? Many factors contribute to menopausal weight gain, but the biggest one is changing hormones. During menopause, estrogen levels drop. Hormone fluctuations can mess with your appetite, causing you to feel hungrier and eat more than usual. Changes in estrogen can also affect how many calories you burn overall, including at rest. They can also promote belly fat gain. Menopausal weight gain may also result from: -Muscle loss -Food cravings -Decreased movement -Insufficient sleep How can you lose weight during menopause? Research suggests that losing weight during menopause may help its symptoms, including hot flashes. Source: Kroenke CH, et al. (2012). Effects of a dietary intervention and weight change on vasomotor symptoms in the Women’s Health Initiative. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428489/ Steps to lose weight during menopause: -Eat nutritious foods, to naturally eat fewer calories than your body burns -Incorporate more movement into day-to-day activities -Drink more water, which can help suppress your appetite, stimulate your metabolism, increase the breakdown of fat for energy, and keep you hydrated -Get enough sleep Weight loss medications can also help: -Suppress appetite -Curb food cravings -Increase feelings of fullness after meals -Control blood sugar Visit forhers.com to learn more about prescription weight loss treatments and connect with a provider to help determine what may be appropriate for you. Visit our blog to learn more: https://www.forhers.com/blog/how-to-lose-weight-during-menopause Subscribe to Hers on YouTube: https://www.youtube.com/@forhers?sub_confirmation=1 Why Hers? ✨Affordable, personalized treatment plans ✨100% online process, including ongoing care and support ✨Free, discreet shipping to your door, if prescribed The information provided here is NOT MEDICAL ADVICE and is for informational purposes only. Please contact your provider if you have any further questions regarding your condition or treatment. Not available everywhere. Weight Loss by Hers includes compounded products which are not approved or verified for safety, effectiveness, or quality by the FDA. Prescription products require a provider consultation to determine if they are medically appropriate and necessary for you. See website for full details, important safety information, and restrictions, including online provider requirements. Connect with Hers on social: Facebook: https://www.facebook.com/wearehers X: https://twitter.com/wearehers Instagram: https://www.instagram.com/hers/ TikTok: https://www.tiktok.com/@hers

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Many people worry whether using protein powder accelerates kidney damage, hair loss and acne. Here's a look at what the science tells us about these questions: 00:00 Intro 00:30 Kidney Damage People who already have kidney disease are often advised to follow a low protein diet. This is because eating protein can increase the filtration rate, and therefore put extra pressure on the kidney. In the long term, there is some research that suggests that a high protein diet may make kidney damage worse in people who already have kidney disease. But just because something is true in people who already have kidney disease, doesn't mean that it also applied to people who are healthy. Healthy kidneys have an incredible ability to adapt. We know that people can live with one kidney because a healthy kidney is easily able to adapt to a higher workload without any consequence. A recent study specifically that looked at the impact of a high protein diet in healthy people, found no negative effect of a high protein diet on kidney function: 02:10 Hair Loss Hair loss in men occurs because of a combination of genetics and the effect of testosterone. In men, testosterone is converted into DHT in the hair follicles. In men who are genetically at risk, testosterone converts large hair follicles into to small hair follicles that produce thin hair. I couldn't find any direct research into protein intake and hair loss. So to answer the question, I looked for indirect evidence that would link protein and hair loss. Since testosterone is a major driving factor for hair loss, if a high protein diet increases testosterone levels, that could link protein intake and hair loss. A couple of small studies suggest that protein intake doesn't increase testosterone levels, so as far as the research goes, it is unlikely that protein powder causes hair loss. 03:41 Acne Acne occurs due to a combination of genetics, normal skin bacteria, immune function and sensitivity to hormones. Sebaceous glands in the skin produce an oily substance called sebum, that normally lubricates the skin. In people who have acne, excess sebum clogs up skin pores and leads to inflammation. Hormones such as testosterone, DHT and Insulin-like Growth Factor (IGF) all increase the activity of sebaceous glands, and could therefore make acne worse. As I mentioned earlier, protein intake probably doesn't increase testosterone levels. There is some low quality evidence that dairy products may increase IGF levels and therefore accelerate acne in those people who are at risk. To further support this claim, there are case reports that whey protein made acne worse in a handful of patients. So it is possible that whey protein may make acne worse. A possible remedy for this is to use soy or plant based protein if you have severe acne. #protein #fitness #docunlock Full transcript: https://www.docunlock.org/youtube/is-protein-powder-bad-for-you All DocUnlock content is for educational purposes only and is not intended as a substitute for medical advice, diagnosis and treatment. Please read our Disclaimer: https://www.docunlock.org/medical-information-disclaimer -- References and Further reading: Changes in Kidney Function Do Not Differ between Healthy Adults Consuming Higher- Compared with Lower- or Normal-Protein Diets: A Systematic Review and Meta-Analysis - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236074/ History of dietary protein and Kidney Damage: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262767/ Guyton and Hall Textbook of Medical Physiology 12ed (p321) Androgens and Alopecia: https://www.ncbi.nlm.nih.gov/pubmed?term=12573818 Dietary protein intake and testosterone 1: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2129168/ Dietary protein intake and testosterone 2: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778704/ Prevalence of acne: https://www.ncbi.nlm.nih.gov/pubmed?term=17945383 IGF and Pathogenesis of acne: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318522/ IGF-1, DHT and Acne: https://www.ncbi.nlm.nih.gov/pubmed/15781674 Case reports: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350548/ Case reports: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900340/ -- Video credits: Certain illustrations adapted from https://www.svgrepo.com/ and https://www.freepik.com/ (macrovector / Freepik) Music: Motionarray (affiliate link): https://motionarray.com?ref=ankitgupta1 KSMK - First Love. Music promoted by Vlog No Copyright Music. Video Link: https://youtu.be/MxN26gVqG_Q -- DocUnlock is a new YouTube channel with one purpose: to help people make better decisions about their own health, and the health of their families. SUBSCRIBE to our channel to stay in the loop! Follow us: https://www.facebook.com/DocUnlocked/ https://twitter.com/DocUnlocked Sign up to the DocUnlock Insider mailing list to receive updates direct to your inbox: https://www.docunlock.org/home/#docunlockinsider Website: https://www.docunlock.org/

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Transformational Journey of Missy Elliott

Missy Elliott, the iconic rapper, producer, and songwriter, has long been synonymous with the innovative spirit of hip-hop and R&B. She has not only mesmerized audiences with her catchy tunes and electrifying performances but also resonated deeply with fans due to her bold personality and unique style. However, in recent years, Missy has embraced a transformational journey that goes beyond her music and fashion. At the age of 50, she became an inspiration for many by showcasing an impressive weight loss journey, shedding significant pounds from 200 to 130. This transformation reflects not just a physical change but also a powerful narrative of personal growth, resilience, and redefining what it means to be healthy and vibrant in today’s world.

Missy Elliott’s journey to this remarkable weight loss is a testament to her determination and adaptability. Navigating the challenges of the entertainment industry, including the pressures of image and health, she prioritized her wellbeing. In doing so, she acknowledged that healthy living is not solely about aesthetics but is rooted in feeling good from the inside out. Her story speaks volumes about the importance of mental and emotional wellness alongside physical health. Missy’s transformation is a reminder that taking charge of one’s health is a powerful declaration of self-love, particularly for those in the public sphere who often face judgment regarding their appearance.

Moreover, Missy’s experience highlights the multifaceted approaches to weight loss and health improvement that individuals can adopt. Through a combination of regular exercise, balanced nutrition, and a positive mindset, she carved out a path that many emulate. For Missy, this transformation signifies breaking free from past constraints while embodying confidence and strength in her identity. As she celebrates her successes, Missy inspires countless others, regardless of age, to undertake their unique journeys toward wellness, reminding everyone that change is possible at any stage of life.

The Catalyst Behind the Transformation

At the heart of Missy Elliott’s inspiring transformation lies the catalyst that prompted her to re-evaluate her lifestyle and health. Like many individuals, she faced various life challenges that made her reflect on her priorities. The pressures of the music industry, alongside personal health complications, served as critical turning points. These factors made her recognize the need for change, not just to feel better about her appearance but to ensure longevity and vitality in her life.

In particular, Missy encountered issues related to her weight that directly affected her overall health. Her journey towards rectifying these concerns started with image-related struggles that many can relate to. Ascending into the limelight, she has been subjected to public scrutiny, leading to moments of self-doubt and insecurity. Such experiences can compel anyone to reconsider their choices, notably when it comes to physical health. Therefore, the decision to embark on her weight loss journey represented both a personal challenge and a proactive approach to reclaiming her health.

Ultimately, the desire for a healthier lifestyle became central to her transformation. Recognizing that sustainable change required dedication, Missy committed herself not only to losing weight but to embracing a holistic approach to well-being. This protagonist arc in her life story showcases that even individuals in sought-after positions face struggles, and the ability to reflect on these challenges is a vital step toward personal development. Resonating with various audiences, her experience serves as both motivation and solidarity to anyone else grappling with similar issues.

The Role of Nutrition in Missy Elliott’s Journey

Nutrition undoubtedly plays a pivotal role in Missy Elliott’s successful weight loss journey. Upon deciding to prioritize her health, Missy delved into understanding the importance of a balanced and nutritious diet. Previously, those unfamiliar may assume that celebrity diets revolve around restrictive eating or fads. However, Missy’s philosophy focused on moderation, informed choices, and embracing natural foods. This shift from processed ingredients to whole foods, lean proteins, fruits, and vegetables marked a significant turning point in maximizing her nutritional intake.

Understanding the importance of meals not just as necessary fuel but as an opportunity to nourish body and mind became a fundamental aspect of her transformation. Missy’s approach toward food involved a commitment to mindful eating. By dissolving the habits of mindless consumption, she began paying attention to the emotional triggers that often lead to overeating. Learning to listen to her body instead of adhering to external pressures allowed her to reshape her relationship with food, reinforcing positive eating habits that would last long into the future.

Furthermore, she emphasized flexibility within her nutritional regimen, allowing herself some indulgences without feeling guilty. This balance prevented burnout and ensured that her journey remained enjoyable and sustainable. By sharing this evolving narrative, Missy advocates a powerful message: health should never stem from deprivation but should instead foster joy and a sense of empowerment. Her commitment to nutrition highlights a crucial component of the celebratory nature of health, encouraging fans to rethink their approaches toward food choices in a manner that honors their bodies and lifestyles.

Embracing Fitness and Physical Activity

Complementing her nutritional adjustments, physical activity played an instrumental role in Missy Elliott’s incredible transformation. As an entertainer known for her dynamic performances, she possessed an innate understanding of the importance of movement. However, the focus of her fitness journey shifted towards structured exercise routines, enabling her to cultivate strength, endurance, and flexibility which all coalesce toward attaining her weight loss goals.

Engaging in various workout styles, Missy diversified her approach to fitness, incorporating elements of cardio, strength training, and even dance-based workouts. This multifaceted strategy not only kept her routine exciting but also ensured her body continually faced new challenges, promoting better results. She turned to professional trainers and fitness experts who provided her with personalized plans, thus optimizing her workouts according to her specific needs and aspirations.

The social aspect of fitness also contributed significantly to Missy’s journey. Engaging with friends and fellow fitness enthusiasts established a support system that encouraged accountability and camaraderie. Understanding that she was not alone in her struggles and successes helped Missy celebrate each milestone alongside a community that empowered her. The integration of both solitary workouts and group exercises ultimately enriched her physical activity experience, reinforcing the value of fitness beyond just weight loss—it aligned with a greater sense of purpose, joy, and belonging.

Missy Elliott’s Mental and Emotional Resilience

Alongside the physical dedicated efforts, Missy Elliott’s weight loss journey exemplifies the critical importance of mental and emotional resilience. Recognizing weight management is not solely about body image but significantly involves one’s mindset, she made it a priority to cultivate a positive internal narrative. Shifting from self-doubt and negativity to self-acceptance and empowerment constituted a fundamental transformation influencing her overall progress.

A pivotal aspect of her emotional journey embraced vulnerability. Instead of concealing struggles with body image, Missy courageously shared her story with her audience, shedding light on the experiences surrounding weight fluctuations. By offering insight into her vulnerabilities, she dismantled the stigma often associated with discussions about body image within the entertainment industry. This openness transformed Missy into a powerful advocate for mental health, encouraging fans to embark on their journeys focused not only on physical change but also on nurturing emotional wellbeing.

Furthermore, Missy incorporated mindfulness practices into her daily life, helping cultivate self-awareness and emotional regulation. Engaging in meditation, journaling, and supportive discussions provided her with tools to process emotions effectively. These practices established a framework for coping with the plethora of stressors inherent to both life and the pursuit of health. By investing in her mental health, Missy countered the societal pressures that typically undermine self-esteem, allowing her to rediscover her confidence and love for herself. Through her stories, Missy Elliott encourages individuals to prioritize mental and emotional resilience on their paths to wellness and self-discovery.

Legacy of Transformation and Inspiration

Missy Elliott’s transformation signifies far more than a numerical weight change; it embodies a legacy of inspiration that resonates across diverse demographics. By adeptly navigating her journey and sharing her experiences, Missy impacts not only her fans but also broader communities seeking motivation in their pursuit of health and wellness. The openness surrounding her struggles, triumphs, setbacks, and realizations serves as a powerful narrative that encourages others to break free from societal constraints and stereotypes.

As a prominent figure in pop culture, Missy’s influence extends beyond music. She embodies the notion that there is no age limit to transformations, asserting that individuals can embark on significant improvements regardless of their starting points. She inspires her followers significantly through her philosophies about embracing one’s own journey instead of conforming to societal expectations, ultimately prompting discussions about body positivity, wellness, and self-acceptance.

The conversations ignited by Missy’s journey have led to a greater understanding of the importance of holistic health practices. She showcases that health embodies the harmonious integration of physical, emotional, and mental aspects. Her narrative invites ongoing dialogue about the complexities of weight management, the importance of a supportive community, and the immeasurable strength derived from resilience. As she continues to inspire future generations, Missy Elliott’s legacy reinforces the idea that personal transformations can ignite broader cultural shifts, forwarding conversations about wellness, self-love, and the limitless capacity for growth in our lives.

In Summary: Q&A About Missy Elliott’s Weight Loss Journey

Missy Elliott’s extraordinary weight loss journey has prompted numerous questions from fans and observers eager to learn more about her experience. One common question is, what motivated Missy to initiate this transformation? As she publicly shared, her health concerns and desire for a vibrant life spurred her commitment to embracing healthier choices, showcasing the importance of visibility regarding personal struggles.

Another frequently asked question revolves around her dietary changes. Missy highlighted the significance of incorporating whole foods while indulging in moderation. She affirms that making informed choices, understanding the nutritional value of what we consume, and moving away from processed foods have greatly contributed to her transformation. This approach underscores that healthy eating does not equate to deprivation but is a balance of nutrition and enjoyment.

People also inquire about her fitness regimen and how she has maintained motivation. By diversifying her workout routines and emphasizing the joy found in movement rather than viewing it as a chore, Missy certainly remained motivated. Additionally, building a supportive community around her fitness endeavors played a substantial role. She showcases that accountability and connection enable sustainable changes on her journey toward wellness.

Lastly, many wonder about the emotional aspects of her transformation. Through her courageous vulnerability and commitment to self-acceptance, Missy is a strong advocate for mental and emotional health, urging others to embrace their journeys authentically. This resilience highlights the necessity of nurturing our mindset alongside physical goals, reinforcing that meaningful change thrives in an environment of self-love.

To conclude, Missy Elliott’s journey from 200 to 130 pounds exemplifies not just a narrative of weight loss but one of holistic transformation grounded in determination, resilience, and self-acceptance. She stands as a testament to the power of change, inspiring countless individuals still fighting their challenges to prioritize their health and wellbeing, and inviting everyone to pursue a fulfilling life centered on love, acceptance, and continuous growth.

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Truvia natural sweetener is the key ingredient that sets Truvia Keto Gummies apart from other sweet treats on the market. Made from the stevia leaf, Truvia natural sweetener is a plant-based sweetener that provides a deliciously sweet taste without the negative effects of sugar.

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There are endless ways to incorporate Truvia Keto Gummies into your diet to satisfy your sweet cravings while staying on track with your keto goals. You can enjoy these gummies as a standalone treat, or get creative and use them as toppings for your favorite keto desserts.

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Q: Are Truvia Keto Gummies suitable for individuals with nut allergies?

A: Yes, Truvia Keto Gummies are nut-free, making them safe for individuals with nut allergies to enjoy as a sweet treat.

Q: How many gummies come in a serving of Truvia Keto Gummies?

A: Each serving of Truvia Keto Gummies typically contains around 5-6 gummies, depending on the flavor and size of the gummies.

Q: Can I eat Truvia Keto Gummies if I’m not following a ketogenic diet?

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