Transcript New Weight Loss Drugs Showing Promise For Sleep Apnea ReliefThe DARK TRUTH About Ozempic Weight Loss Revealed In this episode you here some TRAGIC story's about the consequences of Ozempic. Can you magically lose weight with Ozempic, or is it a silent killer? Find out here. Part 1 of 3 #ozempic #killer Watch the entire video for more information!Weightloss Loseweightfast Bellyfat Youtubeshorts Shorts Viralshorts Fitness Motivation FitA video summary from the original blog "Plenity vs. Semaglutide: In-Depth Comparison of Two Leading Weight Loss Treatments" published here: https://bmidoctors.com/plenity-vs-semaglutide-in-depth-comparison-of-two-leading-weight-loss-treatments/Obesity Weight Loss Dr Venkatramana Hegde Veda Wellness Center Nisarga Mane Sirsihttps://promo.promocurso.shop/lipoInsights Into Semaglutide Pills For Weight LossCardioNerds (Drs. Gurleen Kaur and Richard Ferraro) and episode FIT Lead Dr. Spencer Carter (Cardiology Fellow at UT Southwestern) discuss the clinical implementation of GLP-1 receptor agonists with Dr. Neha Pagidapati (Faculty at Duke University School of Medicine). In this episode of the CardioNerds Cardiovascular Prevention Series, we discuss the clinical implementation of glucagon-like peptide-1 (GLP-1) receptor agonists. We cover the clinical indications, metabolic and cardiovascular benefits, and potential limitations of these emerging and exciting therapies. Show notes were drafted by Dr. Spencer Carter. Audio editing was performed by CardioNerds Academy Intern, student Dr. Pacey Wetstein. This episode was produced in collaboration with the American Society of Preventive Cardiology (ASPC) with independent medical education grant support from Novo Nordisk. See below for continuing medical education credit. Claim CME for this episode HERE. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls and Quotes - Clinical Implementation of GLP-1 Receptor Agonists GLP-1 agonists work through a variety of mechanisms to counteract metabolic disease. They increase insulin secretion, inhibit glucagon secretion, slow gastric motility, and increase satiety to limit excess energy intake. Patients with type II diabetes and an elevated risk for atherosclerotic cardiovascular disease should be considered for GLP-1 agonist therapy regardless of hemoglobin A1c. GLP-1 agonists offer significant ASCVD risk reduction even in the absence of diabetes. Newer data suggest a significant reduction in cardiovascular events with GLP-1 agonist therapy in patients who are overweight or obese and have a prior history of heart disease. GLP-1 agonists should generally be avoided in patients with a history of medullary thyroid cancer or MEN2. As these medications slow gastric emptying, relative contraindications include history of recurrent pancreatitis and gastroparesis. GLP-1 agonists should be initially prescribed at the lowest dose and slowly uptitrated to avoid gastrointestinal side effects. Show notes - Clinical Implementation of GLP-1 Receptor Agonists What were the groundbreaking findings of the STEP1 and SURMOUNT-1 trials and how these impact cardiovascular wellness? The STEP1 and SURMOUNT trials demonstrated sustained clinically relevant reduction in body weight with semaglutide and tripeptide, respectively, in patients with overweight and obesity. As obesity is an important risk factor for the development of cardiovascular disease, weight reduction meaningfully contributes to cardiovascular wellness. What were the findings of the LEADER trial and their implications for patients with type II diabetes and high cardiovascular risk? The LEADER trial demonstrated a significant reduction in the rate of cardiovascular death, nonfatal MI, or nonfatal stroke in patients with type II diabetes treated with liraglutide. GLP-1 receptor agonist therapy should be considered in all patients with type II diabetes and elevated ASCVD risk regardless of A1c or current hyperglycemic therapy. What are current indications for GLP1 agonists in the context of cardiometabolic disease. GLP-1 receptor agonists should be considered in patients with type II diabetes and high ASCVD risk OR patients without diabetes who are overweight/obese and have a history of cardiovascular disease. What are important side effects or contraindications to GLP1 agents when used for cardiovascular risk reduction and wellness? GLP-1 receptor agonists should be avoided in patients with a history of medullary thyroid cancer or MEN2. Relative contraindications include recurrent pancreatitis, gastroparesis,Weight Loss Exercises At Home Workout Fitness Evdeshorts Evdespor Everyone Spor Shortsvideo Managing Expectations: Average Weight Loss with Semaglutide When it comes to weight loss medications, managing expectations is crucial. One such medication that is gaining attention for its weight loss properties is semaglutide. In this article, we will discuss the average weight loss that can be expected with semaglutide, as well as how to set realistic goals and understand the factors that can impact individual results. The Science Behind Semaglutide Semaglutide is a medication that belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. It works by mimicking the effects of a hormone that helps regulate blood sugar levels and appetite. In addition to its primary use in the treatment of type 2 diabetes, semaglutide has also been shown to promote weight loss in clinical trials. Studies have found that semaglutide can help individuals lose a significant amount of weight when used as part of a comprehensive weight loss program that includes a reduced-calorie diet and increased physical activity. The exact mechanism by which semaglutide promotes weight loss is not fully understood, but it is thought to involve a combination of appetite suppression, slowed gastric emptying, and increased energy expenditure. One of the key advantages of semaglutide for weight loss is its long-acting formulation, which allows for once-weekly dosing. This convenience can make it easier for individuals to adhere to their treatment regimen and achieve sustained weight loss over time. However, like any medication, semaglutide is not a magic bullet and results can vary from person to person. Setting Realistic Expectations It is important for individuals considering semaglutide for weight loss to set realistic expectations and understand that results may not be the same for everyone. While some individuals may experience rapid and significant weight loss with semaglutide, others may see more modest results. Factors such as age, gender, baseline weight, genetics, and lifestyle habits can all play a role in determining individual outcomes. Before starting treatment with semaglutide, it is recommended to have a discussion with a healthcare provider to establish realistic weight loss goals and develop a personalized treatment plan. It is also important to have realistic expectations about the potential side effects of semaglutide, which can include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and temporary, but they can impact adherence to treatment. Monitoring Progress and Adjusting Goals Monitoring progress is essential when using semaglutide for weight loss. Regular check-ins with a healthcare provider can help track weight loss progress, adjust treatment as needed, and address any challenges or concerns that may arise. It is important to remember that weight loss is a journey that may have ups and downs, and patience and persistence are key. If weight loss plateaus or stalls while using semaglutide, it may be necessary to make adjustments to the treatment plan. This could include increasing physical activity, fine-tuning dietary habits, or potentially adjusting the dose of semaglutide. A healthcare provider can help guide these decisions and provide support along the way. Conclusion In conclusion, managing expectations is important when using semaglutide for weight loss. While this medication has shown promising results in clinical trials, individual outcomes can vary. 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