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Novo Nordisk A/S’s shares fell by the most on record after a failed attempt to leapfrog rival Eli Lilly & Co. in the red-hot market for obesity drugs. Novo’s experimental obesity shot CagriSema helped patients lose an average of 20.4% of their weight over 68 weeks, short of the 25% weight loss that Novo had repeatedly predicted for its next-generation product. The study results were roughly in line with the performance of Eli Lilly’s Zepbound shot, which is already on the market and competes with existing Novo treatment Wegovy. Lilly is also working on a next-generation medicine, called retatrutide, which helped people lose up to about 24% of their weight in a mid-sized study last year. WATCH: Emily Field, Barclays’ head of European pharmaceutical research, says the selloff in Novo Nordisk’s shares is an overreaction. Novo’s shares plunged as much as 27% in Copenhagen, and are now down 15% for the year after a runup on the strength of Wegovy sales. Shares of Eli Lilly jumped 10% in premarket US trading. The share decline briefly knocked more than $120 billion from Novo’s market value. The results may suffice for approval for CagriSema, but they leave Novo with issues positioning the drug in the market, Simon Baker, an analyst for Redburn, said in a note. “They sought a superior result to Lilly and got one that is the same,” Baker said. Novo said it will start another trial in the first half of next year to help find out how best to boost patients’ doses. The company expects to seek regulatory approval for CagriSema toward the end of next year, a spokeswoman said in a statement. The study is one of the most anticipated this year in the field. Novo has been counting on CagriSema to help it ward off a growing roster of competitors, led by Eli Lilly, in a weight-loss market that’s predicted to grow to nearly $130 billion by 2030. For more on the results, Paul Sweeney and Norah Mulinda speak with Bloomberg Intelligence senior pharma analyst John Murphy. -------- Watch Bloomberg Radio LIVE on YouTube Weekdays 7am-6pm ET WATCH HERE: http://bit.ly/3vTiACF Follow us on X: https://twitter.com/BloombergRadio Subscribe to our Podcasts: Bloomberg Daybreak: http://bit.ly/3DWYoAN Bloomberg Surveillance: http://bit.ly/3OPtReI Bloomberg Intelligence: http://bit.ly/3YrBfOi Balance of Power: http://bit.ly/3OO8eLC Bloomberg Businessweek: http://bit.ly/3IPl60i Listen on Apple CarPlay and Android Auto with the Bloomberg Business app: Apple CarPlay: https://apple.co/486mghI Android Auto: https://bit.ly/49benZy Visit our YouTube channels: Bloomberg Podcasts: https://www.youtube.com/bloombergpodcasts Bloomberg Television: https://www.youtube.com/@markets Bloomberg Originals: https://www.youtube.com/bloomberg Quicktake: https://www.youtube.com/@BloombergQuicktake

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Understanding Lizzo’s Transformation Journey

In recent times, Lizzo has captivated audiences not only with her musical talent and empowering messages but also with her stunning physical transformation. The singer, flutist, and body positivity advocate has reportedly lost around 50 pounds in just six months, sparking conversations about her journey toward healthier living. It’s essential to note that Lizzo’s weight loss has not merely been a matter of aesthetics; rather, it represents significant changes in her lifestyle, mindset, and overall approach to health and wellness. The motivation for her transformation stems from a desire to feel better both physically and emotionally, rather than subscribing to societal pressures regarding body image. This article delves into the secrets behind Lizzo’s remarkable weight loss and the comprehensive changes that have accompanied her journey.

Lizzo’s approach to weight loss is multi-faceted, as she emphasizes the importance of well-being over mere appearance. This means redefining success in her health journey, focusing on sustainable changes rather than quick fixes. Throughout her journey, Lizzo has openly communicated that self-love is at the core of her efforts. Her public statements and social media posts reflect her commitment to embracing her body while simultaneously making choices that support her health goals. This mindset is crucial, as it underscores the emotional and psychological aspects of weight loss that are often overlooked in traditional weight loss narratives. By openly discussing her journey, Lizzo challenges the stigma associated with weight loss and encourages a broader conversation about body positivity, mental health, and individual wellness journeys.

The entertainers’ success invites a closer examination of how she achieved her weight loss goals. After typically enjoying a lifestyle characterized by indulgent meals and a busy, high-pressure career as a global superstar, Lizzo has taken deliberate steps to shift toward a more balanced lifestyle. This balance encompasses nutrition, exercise, and emotional health, creating a holistic approach to her physical transformation. There are three key elements that contributed to Lizzo’s success in dropping 50 pounds in a relatively short period: dietary adjustments, fitness regime changes, and crucially, changing her mindset toward health. Each of these factors plays a significant role in her weight loss story and can serve as inspiration for others seeking to make positive changes in their lives.

Nutritional Changes: Eating for Health, Not Just Weight Loss

One of the most significant changes in Lizzo’s lifestyle was her approach to nutrition. Lizzo has shared insights into how she modified her diet to promote healthy weight loss without feeling deprived. The singer focused on incorporating more whole, nutrient-dense foods into her meals, emphasizing fruits, vegetables, lean proteins, and whole grains. This shift not only contributed to her weight loss but also improved her overall energy levels and well-being. Focusing on these nourishing foods allowed her to enjoy meals that are both satisfying and beneficial to her health, promoting a positive relationship with food.

Another aspect of Lizzo’s nutritional changes was a reduction in processed foods and sugars. While she has always been open about her love for food, stylizing her cooking and eating habits allowed for a more balanced approach. By decreasing the intake of high-calorie, low-nutrient foods, she enabled her body to function optimally. Lizzo understands that food is not just fuel; it is an integral part of cultural identity and personal joy. Therefore, she sought to strike a balance that honors her love for food while aligning with her health goals. By substituting processed snacks with healthier alternatives, she has managed to keep her cravings in check without sacrificing her enjoyment of food.

Lizzo’s commitment to mindful eating also plays a crucial role in her transformation. Mindful eating involves being conscious of the total experience of eating, which includes savoring flavors and recognizing hunger cues. This practice allows individuals to develop a healthier approach to food by understanding emotional triggers for eating and making intentional choices. For Lizzo, mindful eating means loving her body enough to care for it while still enjoying the delights of culinary experiences. This philosophical shift complements her dietary changes, leading to sustainable habits that positively impact her physical and emotional health.

The Role of Physical Activity: Finding Joy in Movement

Alongside her nutritional adjustments, Lizzo has embraced a more active lifestyle, integrating regular physical activity into her routine. While many people consider exercise a chore or obligation, Lizzo has made an effort to find joy and fun in movement. From engaging in dance sessions to participating in fitness classes, she has sought out activities that bring her happiness while also contributing to her weight loss journey. This perspective on exercise promotes lasting engagement, as it transforms working out from a tedious requirement into an enjoyable pastime.

Another key component of Lizzo’s physical activity routine is consistency. Recognizing that lasting weight loss stems from regular engagement rather than sporadic efforts, she has built a fitness schedule that fits seamlessly into her daily life. Lizzo’s philosophy emphasizes that any movement is better than none, inspiring others to find little ways to be active throughout the day. Consistent physical activity also provides mental health benefits: the release of endorphins leads to enhanced mood and wellness, reinforcing the positive cycle of her transformational journey.

These elements underscore the importance of creating a fitness routine that aligns with personal interests, a can-do attitude, and convenience. By prioritizing enjoyable activities, Lizzo sets the stage for a positive relationship with exercise. Her social media presence often reflects her workouts that are filled with fun, laughter, and self-expression, effectively communicating that fitness doesn’t have to be a monotonous experience. Lizzo’s holistic approach to fitness showcases how transforming one’s mindset around activity can lead to more substantial and lasting results in health and well-being.

Mental and Emotional Well-Being: The Heart of Transformation

While nutrition and physical activity are essential components of Lizzo’s transformation, her mental and emotional well-being plays an equally critical role in her journey. Lizzo has emphasized the importance of self-care and the development of a healthy mindset in achieving her weight loss goals. Recognizing that weight loss can be as much about mental health as it is about physical health, she has actively pursued paths that promote emotional resilience and self-acceptance. This commitment has allowed her to navigate the complexities of her journey with grace and authenticity.

Lizzo’s focus on self-love and self-acceptance encourages an empowering framework for her health journey. Rather than seeking validation from external sources, she cultivates an internal narrative rooted in self-worth. This positive self-talk has allowed her to celebrate victories, whether big or small, reinforcing the idea that well-being extends beyond physical appearance. By recognizing her self-determination and celebrating her curves, Lizzo challenges societal norms and inspires individuals to embrace their bodies while also pursuing their health objectives.

Moreover, the importance of community and support in the weight loss journey cannot be underestimated. Lizzo actively promotes body positivity and encourages conversations around mental health, fostering environments where individuals can share experiences and support one another. This communal approach helps demystify the challenges of weight loss and brings people together in their journeys, offering care and solidarity. By creating a platform of openness and acceptance, Lizzo encourages others to navigate their own weight loss journeys with similar faith in themselves and commitment to emotional well-being.

The Impact of Lizzo’s Journey: Inspiration and Change

Lizzo’s weight loss journey has sparked countless conversations surrounding health and body positivity, impacting not just her fans but society at large. Her transformation showcases that success in health is not confined to societal standards or norms but can vary broadly between individuals. By sharing her experiences, Lizzo invites others to reflect on their relationship with food, exercise, and self-image, emphasizing that the journey to health should be unique and personal.

One of the most significant impacts of her journey is the challenge it poses to traditional narratives surrounding weight loss and body image. Lizzo actively dismantles stereotypes that suggest only thinner bodies can be healthy or desirable. This shift in perception invites broader acceptance and understanding of diverse body types while promoting health as a platform for individual choice rather than societal judgment. Her messages of self-love resonate deeply with fans, many of whom are inspired to embrace their own bodies and prioritize well-being over societal pressures.

Furthermore, Lizzo’s story amplifies the importance of patience and persistence in personal transformation. The journey to health is rarely linear; it requires consistent effort, setbacks, and learning. By advocating for mindful changes and positive self-perception, she teaches that motivation often stems from within and that the process itself can be a valuable learning experience. As audiences witness Lizzo’s evolution, they are reminded that health and happiness can be within reach without succumbing to unrealistic expectations. This enduring message strengthens her influence and resonates across diverse demographics.

Reflecting on Lizzo’s Journey: Questions Answered

In reflection of Lizzo’s impressive weight loss journey, many may wonder about the principles that guided her through the transformation. A common question arises about whether Lizzo followed a specific diet or workout plan to achieve her weight loss. In her journey, Lizzo adopted a balanced approach, focusing on moderate changes in her eating and physical activity habits rather than adhering strictly to a particular diet. This allowed her to incorporate healthy choices into her lifestyle naturally, providing a sustainable approach.

Another question often posed is whether Lizzo experienced challenges or setbacks during her journey. The answer is undoubtedly yes—like many individuals undertaking a weight loss journey, Lizzo faced obstacles and moments of difficulty. However, she utilized these experiences as learning opportunities, cultivating resilience and reinforcing her commitment to self-acceptance. Her story serves as a reminder that setbacks are a natural part of the process and that how one responds to those challenges ultimately shapes success.

Many also inquire about the impact of her public persona on her weight loss journey. Lizzo has navigated the complexities of fame with honesty and openness, utilizing her platform to advocate for body positivity and mental health. By sharing her experiences authentically, she provides encouragement and solidarity to those facing similar challenges. Meshing personal experiences with her public image, Lizzo has fostered a movement that encourages individuals to pursue healthier lifestyles while celebrating their unique beauty. This transformative journey not only enhances her own life but has the power to inspire countless others on their paths to well-being and self-love.

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Latisa S. Carson, M.D. is a board-certified physician in Obstetrics and Gynecology and a medical weight loss specialist and is board-certified in Obesity Medicine and is a member of the Obesity Medicine Association. She is the only female African American obstetrician-gynecologist in solo private practice in San Diego County. Her residency training was completed at Southern Illinois University, Springfield, Illinois and her internship year was spent at King/Drew Medical Center in Los Angeles, California. Dr. Carson is a University of Kansas School of Medicine graduate, from Kansas City, Kansas. She has a special interest in helping her community achieve a healthier weight and active lifestyle and offers physicians supervised, medically supported weight loss programs that include nutrition, behavior management, weight loss medication, and exercise guidance. Together Dr. Carson and I dive into all things weight loss from GLP-1 receptors to the incredibly popular Ozempic and semaglutide compounded medicines. Dr. Carson shares her experience with using GLP-1 receptor antagonists with her patients and offers her wisdom regarding the pillars of health that must be supported by practitioners to optimize lasting patient success. She highlights both the negative and positive side effects associated with weight loss medicines, offers guidelines for effectively tapering off medication, and shares insights into the slow but steady functional medicine changes that are coming into traditional medicine. Her advice is both encouraging and pragmatic, and our conversation is filled with insights for any practitioner who is interested in successfully incorporating today’s hottest weight loss medications into their practice. I’m your host, Evelyne Lambrecht, thank you for designing a well world with us. *Episode Resources:* Dr. Latisa Carson https://www.uniquelyfitmedicalweightloss.com/ *Design for Health Resources:* Designs for Health - https://www.designsforhealth.com/ Nutrition Blog: Muscle Tone Matters: The Key to Optimal Body Composition and Metabolic Health - https://www.casi.org/muscle-tone-matters-key-optimal-body-composition-metabolic-health Nutrition Blog: The Hidden Effects: Medications and Their Impact on Your GI Tract - https://www.casi.org/medications-and-their-impact-on-gi-tract Research Blog: Influence of Probiotics on Weight Management in Obesity - https://www.casi.org/node/1557 Research Blog: The Stomach-Brain Axis: Hunger’s Not All in the Mind - https://www.casi.org/node/971 Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog. https://www.designsforhealth.com/research-and-education/education *Chapters:* 00:00 Intro 03:18 Dr. Carson recalls her mother’s experience as a nurse, her own introduction to weight loss medicine, and her initial connection with Designs for Health. 07:20 Defining GLP-1 and GLP-1 receptor agonists and the role of drugs including Ozempic and dual agonist drugs such as Terzepitide in obesity management. 10:30 Key differences between brand names and semaglutide compounded medicines, as well as injected versus oral medicines. 14:10 Semaglutide success rates, adherence rates, and average weight loss goal timelines. 15:15 Dr. Carson’s individualized approach to dosing and titration at every stage of a weight loss journey. 21:30 Dr. Carson’s comprehensive support program includes weekly visits, medicines, diet plans, and frequent patient engagement. 25:35 Muscle mass loss and management of other extreme side effects and complications from these medications. 33:42 Dr. Carson’s experience with favorable side effects in managing other addictions with these medicines. 36:14 Guidelines for tapering off medication and successfully keeping the weight off. 39:00 Addressing the mindset of a patient and past trauma in ways that will be most helpful. 43:25 Dr. Carson shares her desire to integrate functional medicine into her traditional medicine OB practice earlier in her career. 45:35 Detox pathways are a critical first step to weight loss. 51:23 Dr. Carson shares what she has changed her mind about over the course of her career, her personal favorite supplements, and her favorite health practices.

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Semaglutide is a medication that has gained popularity for its potential to aid in weight loss. Originally developed to treat type 2 diabetes, Semaglutide has shown promising results in helping individuals shed unwanted pounds when used in higher doses. In this article, we will explore the weight loss results that one can expect when using Semaglutide, as well as provide insights into how this medication works to promote weight loss.

How Does Semaglutide Promote Weight Loss?

Semaglutide belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. This medication works by mimicking the effects of a naturally occurring hormone in the body called GLP-1. GLP-1 is released in response to food intake and helps to regulate blood sugar levels by stimulating insulin release from the pancreas. In addition to its effects on blood sugar, GLP-1 also helps to reduce appetite and increase feelings of fullness, which can lead to decreased food intake and ultimately weight loss.





When Semaglutide is used in higher doses for weight loss, it has been shown to effectively reduce body weight by targeting the hypothalamus in the brain. The hypothalamus plays a key role in regulating energy balance by controlling appetite, metabolism, and body weight. By targeting this region of the brain, Semaglutide can help to reset the body’s internal weight set point, leading to sustainable weight loss over time.

In addition to its effects on the hypothalamus, Semaglutide has also been found to slow down the emptying of the stomach and reduce food cravings, further supporting weight loss efforts. This medication can help individuals make healthier food choices and reduce their overall caloric intake, which is crucial for achieving long-term weight loss success.

What Results Can You Expect with Semaglutide?

The results of using Semaglutide for weight loss can vary from person to person, but studies have shown that this medication can lead to significant reductions in body weight when used in higher doses. Clinical trials have demonstrated that individuals who took Semaglutide for weight loss experienced an average weight loss of around 15-20% of their initial body weight.

It is important to note that the amount of weight loss achieved with Semaglutide will depend on various factors, including the individual’s starting weight, diet, exercise habits, and overall health status. In general, those who follow a healthy diet and exercise regularly while taking Semaglutide are more likely to see greater weight loss results compared to those who do not make lifestyle changes.

Most individuals who use Semaglutide for weight loss can expect to see gradual progress over time, with the most significant weight loss typically occurring within the first 6-12 months of treatment. It is important to be patient and consistent with treatment, as sustainable weight loss takes time and effort. Working closely with a healthcare provider or weight loss specialist can help individuals set realistic goals and stay on track with their weight loss journey.

Are There Any Side Effects of Using Semaglutide for Weight Loss?

Like any medication, Semaglutide can cause side effects in some individuals. Common side effects of using Semaglutide for weight loss include nausea, vomiting, diarrhea, and constipation. These side effects are typically mild to moderate in severity and often improve with continued use of the medication.

In rare cases, Semaglutide may cause more serious side effects, such as pancreatitis or gallbladder problems. It is important to speak with a healthcare provider if you experience any unusual symptoms while taking Semaglutide for weight loss. Your healthcare provider can help determine if the benefits of using Semaglutide outweigh the risks and provide guidance on how to manage any side effects that may arise.

Overall, Semaglutide has shown to be a safe and effective medication for promoting weight loss in individuals who are overweight or obese. By working to regulate appetite, reduce food cravings, and increase feelings of fullness, Semaglutide can help individuals achieve and maintain a healthier weight over time. It is important to consult with a healthcare provider before starting Semaglutide for weight loss to ensure that this medication is appropriate for your individual needs and health goals.

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When it comes to losing weight, many people look to celebrities for inspiration. Kelly Clarkson, who has been open about her weight struggles in the past, recently revealed her incredible weight loss transformation. Fans are curious about what methods she used to achieve such impressive results. In this article, we take an inside look at what Kelly Clarkson took to lose weight and how it has helped her on her journey to a healthier lifestyle.

The Beginning of Kelly Clarkson’s Weight Loss Journey

Before diving into what Kelly Clarkson took to lose weight, it’s important to understand where her journey began. The Grammy-winning singer has always been open about her struggles with weight and body image. In interviews, she has spoken about how her weight has fluctuated over the years and the challenges she has faced in maintaining a healthy lifestyle.

After giving birth to her two children, Kelly Clarkson found herself at a weight that she was unhappy with. She knew that she needed to make a change for both her physical and mental well-being. This realization marked the start of her weight loss journey, and she was determined to take control of her health.

Like many people, Kelly Clarkson turned to a combination of diet and exercise to help her lose weight. She knew that there was no quick fix or miracle solution, and that sustainable weight loss would require commitment and dedication. With the help of professionals, she developed a plan that would work for her and her lifestyle.

Kelly Clarkson’s Diet Plan

One of the key components of Kelly Clarkson’s weight loss journey was her diet plan. She worked closely with a nutritionist to create a meal plan that was both healthy and sustainable. Instead of following a restrictive diet, Kelly focused on eating whole, nutrient-dense foods that would fuel her body and support her weight loss goals.

Some of the foods that Kelly incorporated into her diet plan included lean proteins, fruits and vegetables, whole grains, and healthy fats. She also made sure to stay hydrated by drinking plenty of water throughout the day. By making smart food choices and paying attention to portion sizes, Kelly was able to see progress on the scale and feel better overall.

Another important aspect of Kelly Clarkson’s diet plan was moderation. She didn’t deprive herself of the foods she loved, but instead learned how to enjoy them in moderation. By allowing herself the occasional treat or indulgence, Kelly was able to stick to her diet plan long-term without feeling restricted or deprived.

Kelly Clarkson’s Workout Routine

In addition to her diet plan, Kelly Clarkson also incorporated a workout routine into her weight loss journey. She worked with a personal trainer to develop a fitness plan that would help her reach her goals and improve her overall health. Kelly’s workout routine included a mix of cardio, strength training, and flexibility exercises.

Some of the exercises that Kelly enjoyed included running, weightlifting, yoga, and dance. By mixing up her workouts and trying new activities, she was able to stay motivated and engaged in her fitness journey. Kelly made sure to schedule regular exercise sessions into her busy schedule, prioritizing her health and well-being.

Consistency was key for Kelly Clarkson when it came to her workout routine. She made exercise a non-negotiable part of her daily routine, finding ways to stay active even on the busiest of days. By staying committed to her fitness plan, Kelly was able to see improvements in her strength, endurance, and overall fitness level.

Results and Reflections

After months of hard work and dedication, Kelly Clarkson has achieved incredible results on her weight loss journey. Fans have been amazed by her transformation and inspired by her commitment to health and wellness. By focusing on a balanced diet, regular exercise, and a positive mindset, Kelly has been able to find success in her weight loss efforts.

Looking back on her journey, Kelly Clarkson has expressed gratitude for the support and encouragement she has received from fans and loved ones. She has also shared how her weight loss has impacted her confidence, energy levels, and overall quality of life. Kelly’s journey serves as a reminder that with determination and perseverance, anything is possible.

As Kelly Clarkson continues on her path to health and happiness, fans can’t help but wonder what the future holds for the talented singer. One thing is for certain – Kelly’s weight loss journey is far from over, and she remains committed to living her best life both on and off the stage. With her positive attitude and never-give-up spirit, Kelly Clarkson is sure to inspire others to take control of their health and make positive changes in their own lives.

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How GLP-1s can improve your over all health: Beyond their primary uses for weight loss & diabetes management, GLP-1s offer a range of potential benefits, including improved heart health, kidney protection, and even potential benefits for brain health and sleep. They may also help with fatty liver disease and reduce joint pain.  * GLP-1s can also increase the production of anti-inflammatory cytokines like IL-10, which can help to restore immune balance and mitigate inflammation.  * Brain-Immune Axis:Some research suggests that GLP-1s can reduce inflammation by acting on the brain, lowering the risk of Alzheimer’s disease & improve cognitive function. * Beneficial Effects in Various Conditions:GLP-1s have shown promise in treating conditions like inflammatory bowel disease (IBD), neurodegenerative diseases, and even some autoimmune conditions.

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Happy 2024! I decided to start things off this year by sharing my experience with the Wegovy semaglutide injections. In this video, I am going to give you some general information about Wegovy and share some of my personal experiences with using wegovy for weight loss over the last 3 months and some of the side effects of wegovy. At the time of this video, I am just getting ready to start the 1.7mg shots. I'm looking forward to continuing to share my weight loss journey with you so make sure you are subscribed so you don't miss out. 5 Tips to Maximize Weight Loss & Limit Side Effects on Semaglutide (Wegovy) https://youtu.be/z2P9tXYE0sc?si=V3H5Y0mCqgH1Jq9e Check out the rest of my weight loss journey here https://www.youtube.com/playlist?list=PLe0JEQ_t8q69JqbtVxeYUyWE3xm_5Nbcy Need Inspiration on what to Eat? Check out my What I Eat in A Day Videos https://www.youtube.com/playlist?list=PLe0JEQ_t8q691oOBwm2Qxk4ZYTJOeSIPL Make sure you hit that subscribe button so you can follow along on my 2023 weight loss journey Follow me on IG @toniakay_ New Intro & Channel art were created by me All music is from epidemicsound