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#바이오 #신약 #한국 #바이오주 #바이오기업 #생명과학 #정보 #과학 #삼천당제약 #삼천당제약전망 #삼천당제약주식 #삼천당제약분석 #디앤디파마텍 #디앤디 #dnd #비만약 #비만치료제 #비만치료제관련주 #의약품 #제약바이오 #비만치료 #이슈 #일라이릴리 #노보노디스크 #위고비 #wegovy #saxenda #삭센다 #spass #science #novonordisk #elililly #pfizer #glp #glp1forweightloss #glp1weightloss #glp1medication @Jeonbashi 1. 경구용 비만치료제 시장, 게임 체인저가 될 수 있을까? 최근 제약·바이오 업계에서 가장 주목받고 있는 키워드 중 하나가 바로 경구용 비만치료제다. 전 세계적으로 비만 환자가 급증하면서 관련 치료제 시장도 빠르게 성장하고 있는데, 현재 글로벌 비만치료제 시장 규모는 약 100조 원에 달하며, 2030년에는 무려 318조 원 규모까지 확대될 것으로 예상된다. 기존의 GLP-1 (Glucagon-like Peptide-1) 기반 비만치료제는 체중 감량 효과가 뛰어나지만, 대부분 주사제로 개발되어 있어 환자들이 지속적으로 자신의 복부나 허벅지에 주사를 놓아야 하는 불편함이 있었다. 그러나 최근 글로벌 제약사들이 알약 형태로 복용할 수 있는 경구용 GLP-1 제제 개발에 성공하면서 비만 치료제 시장의 판도가 바뀌고 있다. 경구용 비만치료제는 주사제 대비 복용이 간편하고, 환자의 심리적 부담을 줄여 치료 순응도를 높일 수 있다는 점에서 더욱 주목받고 있다. 2. 글로벌 제약사들의 움직임과 시장 전망 현재 노보노디스크(Novo Nordisk), 일라이릴리(Eli Lilly and Company), 화이자(Pfizer Inc.), 로슈(Roche) 등 글로벌 빅파마들은 경구용 비만치료제 개발에 박차를 가하고 있다. 특히 노보노디스크는 이미 ‘리벨서스(RYBELSUS)’라는 경구용 GLP-1 제제를 개발해 2019년 FDA 승인을 받았지만, 이는 당뇨병 치료제로만 허가된 상태다. 비만 치료 목적으로 사용하기 위해서는 추가적인 연구와 임상이 필요한 상황이다. 일라이릴리 역시 경구형 GLP-1 후보물질을 개발 중이며, 현재 임상 3상 단계에 접어든 상태다. 화이자와 로슈 또한 GLP-1 계열뿐만 아니라, 새로운 기전을 활용한 경구용 비만치료제 개발을 진행하고 있어 시장의 경쟁이 더욱 치열해지고 있다. 전문가들은 향후 3~5년 내에 경구용 비만치료제가 본격적으로 상용화될 가능성이 높다고 보고 있으며, 이로 인해 기존 주사제 중심의 비만치료제 시장이 빠르게 재편될 것으로 예상된다. 3. 국내 제약사들의 도전과 경쟁력 이러한 변화 속에서 국내 제약 바이오 기업들도 경구용 비만치료제 시장 진입을 위한 연구개발에 속도를 내고 있다. 그중에서도 특히 삼천당제약과 디앤디파마텍이 주목받고 있다. 3-1. 삼천당제약, 신기술로 시장에 도전 삼천당제약은 기존 안과 치료제 전문 제약사로 알려져 있지만, 최근 경구용 GLP-1 비만치료제 개발에 본격적으로 뛰어들었다. 이 회사는 ‘S-PASS 플랫폼’이라는 독자적인 기술을 활용해 주사제를 알약 형태로 전환하는 연구를 진행 중이며, ‘SCD506’이라는 경구용 GLP-1 제네릭 치료제를 개발하고 있다. 또한 미국과 일본 등 글로벌 기업들과 협력하여 독점 판매 계약을 체결하는 등 해외 시장 진출도 적극적으로 추진 중이다. 다만, 이 기술이 실질적으로 효과를 발휘할 수 있을지에 대한 검증이 아직 충분하지 않으며, 현재 임상 1상 진입 전 단계에 있어 개발 속도와 성공 가능성에 대한 신중한 접근이 필요하다. 3-2. 디앤디파마텍(D&D Pharmatech), 독자 기술로 차별화 디앤디파마텍은 ‘오랄링크(ORALINK)’라는 자체 기술을 기반으로 펩타이드 기반 약물을 경구용으로 전환하는 연구를 진행하고 있다. 이미 미국 바이오기업 멧세라와 기술 이전 계약을 체결하며 글로벌 시장에서도 기술력을 인정받고 있으며, 현재 미국에서 임상 1상을 진행 중이다. 하지만, 아직 임상 초기 단계이기 때문에 불확실성이 크고, 글로벌 빅파마들과의 경쟁에서 살아남기 위해서는 추가적인 연구개발과 차별화된 전략이 필요하다. 4. 경구용 비만치료제 시장의 과제와 전망 경구용 비만치료제가 성공적으로 시장에 안착하기 위해서는 몇 가지 해결해야 할 기술적 과제가 있다. 대표적인 문제는 흡수율과 효과성의 입증이다. 현재까지 경구용 GLP-1 제제의 생체이용률은 1% 이하로 매우 낮으며, 복용 후 일정 시간 금식을 해야 하는 불편함도 있다. 이러한 문제를 해결하기 위해서는 약물의 흡수율을 높이면서도 체중 감량 효과를 유지할 수 있는 새로운 제형 기술이 필요하다. 또한, 글로벌 빅파마들이 막대한 연구개발 비용을 투자하며 시장을 선점하고 있는 만큼, 국내 기업들이 경쟁력을 갖추기 위해서는 기술력뿐만 아니라, 해외 시장 진출 전략도 필수적이다. 5. 앞으로의 전망, 그리고 여러분의 생각은? 경구용 GLP-1 비만치료제는 앞으로 비만 치료의 패러다임을 완전히 바꿀 게임체인저가 될 가능성이 높다. 하지만, 글로벌 제약사들이 빠르게 시장을 선점하는 가운데, 국내 기업들이 이를 따라잡을 수 있을지는 여전히 불확실하다. 여러분은 삼천당제약과 디앤디파마텍이 글로벌 시장에서 경쟁력을 가질 수 있다고 보시나요? 댓글로 여러분의 생각을 남겨주시고, 영상이 유익했다면 구독과 좋아요, 알림 설정도 부탁드린다. 영상 제작에 큰 힘이 됩니다! 앞으로도 흥미로운 제약·바이오 소식을 전해드리겠다. 감사합니다 :)

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Download my Lab Recommendations Guide https://app.gohighlevel.com/v2/preview/ciNfJ9f6CcYp2jgGx3Ri?notrack=true#bioindividuality Dr. Sowa is a pioneer in obesity medicine, known for combining scientific expertise with compassionate patient advocacy. She is also the author of the new Ozempic Revolution book. In our discussion, Dr. Sowa shares her insights on GLP-1 medications and their role in metabolic health and weight management, and we tackle some of the biggest misconceptions about these drugs, exploring the differences between Metformin and GLP-1s and examining the damaging effects of ultra-processed foods have on our brains. We discuss the impact of the body positivity movement, yo-yo dieting, and microdosing, and Dr. Sowa offers her perspective on metabolic adaptation. We dive into the science behind how GLP-1s work in the body and some specific concerns about their side effects, and we also provide practical guidance on insurance coverage and answer a broad range of listener questions. #cynthiathurlow #womenshealth #wellness #IF #intermittentfasting #fastingforwomen #bioindividuality #health For more information please visit me here: https://cynthiathurlow.com/ This video is for educational and informational purposes only and solely as a self-help tool for your own use. I am not providing medical, psychological, or nutrition therapy advice. You should not use this information to diagnose or treat any health problems or illnesses without consulting your own medical practitioner. Always seek the advice of your own medical practitioner and/or mental health provider about your specific health situation.

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Salveen Richter, Goldman Sachs lead U.S. biotech analyst, joins 'Squawk on the Street' to discuss Amgen's mid-stage trial results for its experimental obesity drug, why she remains bullish on the company, where to invest in GLP-1 stocks, and more.

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Abnehmen ohne Kohlenhydrate ist eine beliebte Diätform, die immer mehr Anhänger findet. Die Idee dahinter ist einfach: Durch den Verzicht auf Kohlenhydrate sollen die Fettdepots des Körpers angezapft werden und man nimmt dadurch ab. Doch wie funktioniert das genau und birgt diese Diätform auch Risiken?

Vorteile von Abnehmen ohne Kohlenhydrate

Ein großer Vorteil der kohlenhydratarmen Ernährung ist, dass sie in der Regel zu einem schnellen Gewichtsverlust führt. Da der Körper gezwungen ist, auf seine Fettreserven zurückzugreifen, purzeln die Pfunde oft schneller als bei anderen Diäten. Zudem hilft der Verzicht auf Kohlenhydrate dabei, Heißhungerattacken zu vermeiden, da der Blutzuckerspiegel konstanter bleibt.

Weiterhin kann eine kohlenhydratarme Ernährung helfen, den Stoffwechsel anzukurbeln und die Fettverbrennung zu steigern. Viele Menschen berichten zudem von einem verbesserten Hautbild und einer gesteigerten Energie, wenn sie auf Kohlenhydrate verzichten. Zudem kann der Verzicht auf Zucker und Weißmehl langfristig zu einem gesünderen Lebensstil führen.

Ein weiterer Vorteil der kohlenhydratarmen Ernährung ist, dass sie sich leicht in den Alltag integrieren lässt. Viele Lebensmittel ohne Kohlenhydrate sind bereits Bestandteil unserer Ernährung, wie zum Beispiel Gemüse, Fleisch und Fisch. Es gibt zudem unzählige Rezepte und Kochbücher, die sich auf eine kohlenhydratarme Ernährung spezialisiert haben, sodass einem abwechslungsreichen Speiseplan nichts im Wege steht.

Nachteile von Abnehmen ohne Kohlenhydrate

Trotz der vielen Vorteile birgt die kohlenhydratarme Ernährung auch einige Nachteile. So kann es in den ersten Tagen zu starken Heißhungerattacken und Müdigkeit kommen, da sich der Körper erst an die neue Energiequelle gewöhnen muss. Auch kann es sein, dass man sich zunächst schlapp und energielos fühlt, da der Körper weniger Zucker zur Verfügung hat.

Weiterhin kann eine kohlenhydratarme Ernährung zu einem Mangel an wichtigen Nährstoffen führen, da viele Kohlenhydrate auch wichtige Vitamine und Mineralstoffe enthalten. Zudem kann es schwierig sein, sich ausgewogen zu ernähren, da viele Lebensmittelgruppen, die reich an Kohlenhydraten sind, komplett gestrichen werden.

Ein weiterer Nachteil der kohlenhydratarmen Ernährung ist, dass sie für manche Menschen schwer umzusetzen ist. Gerade Personen, die gerne Nudeln, Brot und Süßigkeiten essen, könnten Schwierigkeiten haben, auf diese Lebensmittel zu verzichten. Auch kann es in sozialen Situationen wie Restaurantbesuchen oder Familienfeiern schwierig sein, die Diät einzuhalten.

Tipps für eine kohlenhydratarme Ernährung

Wenn du dich dafür entscheidest, Kohlenhydrate zu reduzieren, gibt es einige Tipps, die dir dabei helfen können, erfolgreich zu sein. Zunächst einmal solltest du darauf achten, ausreichend Gemüse zu essen, um wichtige Vitamine und Mineralstoffe aufzunehmen. Auch Nüsse, Samen und gesunde Fette können dabei helfen, den Körper mit Energie zu versorgen.

Weiterhin ist es wichtig, ausreichend zu trinken, um den Körper zu entgiften und den Stoffwechsel zu unterstützen. Auch regelmäßige Bewegung ist wichtig, um die Fettverbrennung anzukurbeln und den Muskelaufbau zu fördern. Achte zudem darauf, genügend Proteine zu dir zu nehmen, um den Muskelerhalt zu unterstützen.

Schließlich solltest du auf versteckte Kohlenhydrate achten, die sich in vielen Fertigprodukten verstecken können. Studiere die Nährwertangaben auf den Verpackungen genau und bereite möglichst viele Mahlzeiten selbst zu, um die Kontrolle über deine Ernährung zu behalten. Mit etwas Planung und Disziplin kannst du erfolgreich abnehmen, auch ohne Kohlenhydrate.

FAQ von Abnehmen ohne Kohlenhydrate

1. Ist Abnehmen ohne Kohlenhydrate gesund?

Ja, eine kohlenhydratarme Ernährung kann gesund sein, wenn sie ausgewogen gestaltet wird und wichtige Nährstoffe nicht vernachlässigt werden. Es ist jedoch wichtig, sich vor Beginn einer solchen Diät von einem Arzt oder Ernährungsberater beraten zu lassen.

2. Wie schnell kann man durch Abnehmen ohne Kohlenhydrate abnehmen?

Der Gewichtsverlust hängt von verschiedenen Faktoren ab, wie zum Beispiel dem Ausgangsgewicht, dem Geschlecht und dem Aktivitätslevel. In der Regel kann man jedoch mit einer kohlenhydratarmen Ernährung schneller abnehmen als mit anderen Diäten.

3. Kann man sich auch vegan kohlenhydratarm ernähren?

Ja, auch als Veganer ist es möglich, sich kohlenhydratarm zu ernähren. Dabei sollten jedoch alternative Eiweiß- und Fettquellen wie Tofu, Nüsse und Avocado in den Speiseplan integriert werden, um eine ausgewogene Ernährung sicherzustellen.

4. Wie kann man Heißhungerattacken bei einer kohlenhydratarmen Ernährung vermeiden?

Um Heißhungerattacken vorzubeugen, ist es wichtig, regelmäßig zu essen und auf ausgewogene Mahlzeiten zu achten. Auch ausreichend Flüssigkeitszufuhr und gesunde Snacks wie Gemüsesticks oder Nüsse können dabei helfen, Heißhunger zu vermeiden.

5. Ist es möglich, langfristig auf Kohlenhydrate zu verzichten?

Es ist möglich, langfristig auf Kohlenhydrate zu verzichten, jedoch ist es wichtig, dabei auf eine ausgewogene Ernährung zu achten. Es kann sinnvoll sein, nach einer gewissen Zeit langsam wieder mehr Kohlenhydrate in den Speiseplan zu integrieren, um einen Mangel an wichtigen Nährstoffen zu vermeiden.

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You might, 💥 Still be sore from the previous workout 💥 Not have energy after being at work all day 💥 Have other tasks that HAVE to be tended to 💥 Not have the energy or motivation to put forth huge bursts of effort On those days, that’s when L.I.S.S comes in L.I.S.S stands for Low Intensity Steady State Cardio L.I.S.S is any low endurance workouts such as walking, swimming, hiking or cycling that allows you to burn calories while training around 50-75% of your maximum heart rate. Benefits of L.I.S.S includes 💥 Caloric or Fat burn 💥 Ability to multitask 💥 Improvement of cardiovascular capacity 💥 Low risk of injury 💥 Low barrier of entry / participation If you are not sure where to start but want to give LISS a try, follow the prompts in the video above. As much as I love pushing the pace and high intensity workouts, HIIT is NOT NECESSARY for fat loss. There are so many different ways to burn fat and LISS is one of my favorite ways. Which do you prefer? LISS or HIIT? Comment below!