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Jamie Tells the Truth About GLP-1s Downsized Dish with Jamie Selzler – How He Lost 340 Pounds on Zepbound In this episode of The Downsized Dish, Christopher Durham sits down with Selzler, who shares how he lost 340 pounds using the GLP-1 medication Zepbound. Jamie opens up about his experience starting at 652 pounds, the emotional and physical toll of living with severe obesity, and the mindset that helped him transform his life. Filmed in Annapolis, Virginia, during the Your Weight Matters National Convention hosted by the Obesity Action Coalition, this is one of the most honest and inspiring conversations we’ve had. Jamie talks about how he started his GLP-1 treatment with Wegovy, transitioned to Zepbound due to shortages, and has stayed on the medication for nearly two years. Christopher and Jamie cover everything from food noise, and self-discipline to the toxic expectations of diet culture. Jamie explains why exercise wasn't possible at first and how he slowly rebuilt mobility over time. He also shares how he’s shifted his focus from goal weight to input goals like hydration, movement, and consistency. Topics include: • Why it took three months to see results on GLP-1 medication • What to expect with side effects like constipation, fatigue, and food sensitivity • How to keep promises to yourself and build momentum • The power of non-scale victories • Why motivation fades and consistency matters more • Jamie’s plan to hike 20 miles by the end of the year This is a must-watch for anyone treating obesity with GLP-1s or thinking about starting. Jamie brings clarity, encouragement, and practical advice for real people facing real struggles. Follow Jamie on social media and reach out if you need support. His message is simple and powerful: You are not alone, and you deserve a better life. FOLLOW JAMIE: YOUTUBE: @jselzler TikTok: @jamselz IG: @jselzler DOWNSIZED LINKS: Shop our GLP-1 companion products: https://thedownsized.org/downsized-store Visit our website: https://thedownsized.org/ Join us for the Downsized at Sea Cruise 2026: https://thedownsized.org/downsized-at-sea-2026/ Become a channel member and unlock exclusive perks: https://www.youtube.com/@thedownsized/join For sponsorships, brand deals, and press inquiries: https://thedownsized.org/contact/ 00:00 Introduction and Welcome 00:11 Meet Jamie: A Special Guest 00:45 Disclaimer and Social Media Plugs 01:50 Jamie's Weight Loss Journey 02:08 The Role of GLP-1 Medication 02:30 Challenges and Public Speaking 03:04 Mind Pump Podcast Appearance 04:56 Life Changes and Non-Scale Victories 11:33 Exercise and Mobility 17:53 Mindset and Motivation 27:48 Setting Achievable Input Goals 30:52 The Importance of Self-Compassion 32:43 The Journey to Weight Loss 35:07 The Role of GLP-1 Medication 37:04 Managing Side Effects 40:24 Personal Experiences and Advice 42:56 The Emotional Impact of Weight Loss 48:59 Future Goals and Reflections 52:32 Final Thoughts and EncouragementWhat Is Apple Cider Vinegar Apple Cider Vinegar Benefits Bestnatural Diureticsweight Loss Understanding Topamax and Its Role in Weight Loss In recent years, the quest for effective weight loss solutions has become a focal point in health and wellness discussions. Among the various options available, Topamax, a medication primarily used to treat epilepsy and migraines, has gained attention for its potential off-label use in aiding weight loss. As we look toward 2025, the burgeoning interest in Topamax for weight management raises questions about its efficacy, safety, and how it can revolutionize the journey from overweight to healthy, not just physically but also in terms of boosting self-confidence. Individuals struggling with obesity often face a multitude of challenges, including societal stigma, health risks, and personal dissatisfaction with their body image. The role of medication like Topamax provides a beacon of hope for many, as it opens avenues for those looking to change their relationship with food and their body. Weight loss is often portrayed in a simplistic manner: eat less, exercise more. However, the reality is far more complex and influenced by numerous factors including genetics, metabolism, psychological well-being, and even medication. Topamax, or topiramate, works by modulating neurotransmitters in the brain, which can lead to reduced appetite and food cravings, making it easier for individuals to adhere to a caloric deficit needed for weight loss. As the awareness surrounding obesity’s impact on mental health and quality of life grows, understanding medications that can assist in weight management becomes imperative for both healthcare providers and patients. Furthermore, with the increasing prevalence of obesity across all demographics, therapies that can assist in sustainable weight loss are more necessary than ever. By 2025, we anticipate medical advancements and a deeper understanding of obesity, weight loss, and the medications available to assist in these changes. For individuals turning to Topamax, it’s crucial to recognize that while it may certainly assist in weight loss, success also heavily relies on lifestyle modifications, including improved diet and increased physical activity. This comprehensive approach not only promotes physical well-being but also significantly elevates one’s self-esteem and self-image. Transforming your body requires commitment and understanding the nuanced role that such medications can play in that journey will be vital for many who wish to transition from overweight to healthy, both in body and mind. How Topamax Affects Weight Loss Mechanisms The mechanism through which Topamax influences weight loss is multifaceted. Primarily, it impacts the central nervous system by affecting neurotransmitters that regulate appetite and satiety. By increasing feelings of fullness, it helps to curb excessive food intake, which is a common pitfall in weight management. These physiological changes in the body’s response to food can significantly help individuals in controlling cravings that often derail their weight loss efforts. It is important to note that while appetite suppression is beneficial, this medication does not provide a magical solution; rather, it acts as a complementary tool that, coupled with lifestyle changes, can yield significant results. Additionally, studies have shown that Topamax may enhance metabolic rates, allowing the body to burn calories more efficiently. By increasing energy expenditure without the need for rigorous exercise regimes, this effect can be particularly advantageous for those who may be discouraged by traditional weight loss methods. It is essential, however, for individuals considering Topamax not to rely solely on the medication but to integrate physical activity into their daily routine, cultivating a healthier lifestyle in conjunction with the treatment. Moreover, the psychological effects of taking Topamax for weight loss are substantial. Individuals often report a shift in their relationship with food, wherein the desire for unhealthy snacks diminishes over time. The confidence boost that comes from self-discipline, paired with observable weight loss, can encourage more routine exercise and healthier eating patterns. Thus, understanding the implications of Topamax on both physiological and psychological fronts can empower users to maximize their weight-loss journey effectively. Potential Side Effects and Considerations <pWhile many have benefited from using Topamax for weight loss, it is crucial to consider the potential side effects associated with this medication. Many users report side effects that range from mild to severe, impacting their overall experience with the drug. Common side effects include dizziness, fatigue, nausea, and altered taste sensation. These side effects can be disconcerting, especially for those who are already managing other health conditions. Consulting with a healthcare professional before starting Topamax is essential, as they can help navigate the potential risks and adjust dosages accordingly. Furthermore, the long-term implications of using Topamax for weight loss are still being explored. While some individuals find success in losing weight while on the medication, others may experience difficulties when attempting to discontinue treatment. Abruptly stopping the medication could lead to weight regain, thereby negating the progress achieved during the treatment period. It’s important for patients to have realistic expectations and to maintain ongoing communication with their healthcare providers throughout their weight loss journey. Lastly, individuals using Topamax should also be aware of the importance of lifestyle changes that accompany medication use. Relying solely on medication for weight loss is unlikely to yield long-term success. A holistic approach that incorporates behavioral therapy, dietary modifications, and regular exercise is essential to ensuring that weight loss results are sustained over time. Overall, while Topamax can play a vital role in shifting body weight, support systems and healthy habits must also be a priority in the weight loss journey. Incorporating Topamax into a Holistic Weight Loss Program Creating a successful weight loss program that integrates Topamax demands a holistic approach, focusing not only on medication but also on diet and exercise. When embarking on this journey, individuals should consider consultation with nutritionists and fitness experts who can guide them in making informed choices. A well-balanced diet rich in nutrients while low in empty calories can aid in weight loss efforts, synergizing with Topamax’s appetite-suppressing properties to achieve optimal results. Emphasis should be placed on whole foods, including fruits, vegetables, lean proteins, and whole grains, while avoiding highly processed foods that can contribute to weight gain. Moreover, exercise plays a significant role in weight loss and overall health. Incorporating physical activity into daily routines does not always have to be strenuous or time-consuming. Activities can range from brisk walking to yoga, as long as they create a calorie deficit and promote a healthy lifestyle. Setting goals for physical activity can also foster motivation; individuals might aim for specific milestones, such as walking a certain number of steps each day or gradually increasing workout duration. This balanced incorporation of exercise helps counteract any lethargy induced by Topamax and aids in maintaining mental health and ensuring physical fitness during the weight loss journey. It’s crucial to remember that each individual’s journey with Topamax will differ. There may be instances where users experience plateaus or dips in motivation, especially as the excitement of initial weight loss wanes. This aspect underscores the importance of continuous self-reflection, goal reassessment, and maintaining a supportive social circle. Engaging in community activities or online support groups can enhance accountability and provide encouragement. By synergistically combining Topamax with lifestyle changes and a supportive environment, individuals can embark on a sustainable path towards transforming their body and confidence. Empowering Yourself Through Knowledge and Support As with any weight-loss endeavor, educating oneself on what to expect from using Topamax can empower individuals to make informed decisions. Extensive research into the medication’s benefits and side effects lays the groundwork for realistic expectations. Additionally, reading testimonials and engaging in conversations with others who have undergone similar journeys can offer valuable insights into possible challenges and success strategies. Community support can help alleviate feelings of isolation that often accompany weight loss struggles, reinforcing a sense of belonging and motivation. Furthermore, it is essential to have open and ongoing dialogues with healthcare professionals throughout the process. Regular check-ins allow for necessary adjustments in medication dosage, lifestyle recommendations, or even a reassessment of one’s weight loss goals. Healthcare providers can offer tailored advice and resources, ensuring that the journey remains safe and effective. They can help identify any adverse reactions to Topamax while providing alternative avenues should the medication not meet expectations. As Topamax gains momentum as an option for weight loss, its role in 2025 and beyond will likely evolve in tandem with advancements in obesity treatment. Patients should stay informed about the latest research findings and treatment modalities. They must remain proactive in advocating for their health and seeking guidance as they navigate this complex journey towards weight loss and improved self-confidence. Ultimately, the road from overweight to healthy is a multifaceted experience, but with knowledge and support, achieving one’s desired transformation can ultimately become a reality. Summary and Common Questions In summary, Topamax offers a promising avenue for individuals seeking effective weight loss, especially as we advance toward 2025. Its ability to suppress appetite and enhance metabolic rates provides a unique benefit for those struggling with obesity. However, this medication is not a standalone solution and should be paired with lifestyle changes for optimal results. Each person’s experience with Topamax can differ, and understanding its effects, alongside the potential side effects, is crucial for informed decision-making. Many individuals have questions about the long-term effects of Topamax on weight loss and overall health. Queries often arise around the best practices for pairing it with physical activity and dietary changes, as well as how to maintain weight loss after discontinuing the medication. It’s important for users to establish a comprehensive plan that includes ongoing support from healthcare professionals and communities, which can facilitate commitment to a healthier lifestyle. Additionally, potential users frequently inquire about the experiences of others who have utilized Topamax for weight loss. Gathering feedback, stories, and testimonials can provide a well-rounded perspective, enabling individuals to understand possible challenges, various approaches, and results that can be expected during their journey. Armed with this collective knowledge and guided by healthcare support, individuals can confidently embark on their transformative paths, turning aspirations of weight loss into tangible achievements that enhance both physical health and self-esteem. How To Lose Weight Fast 5 Kg Fat Burning Drink Fat Cutter Drink Cumin Water For Weight LossLow Carb Bufffalo Chicken Cauliflower Bake! Alright my buddies we’ve got another super simple recipe. It’s got a ton of protein and is very low carb (keto). It only takes five minutes to throw together and twenty minutes to bake! Leave a comment if you want me to send the recipe to you! Love you 1. In a baking dish combine steamed cauliflower(as much as you want, I just do one bag), shredded chicken (as much as you want) and season those with salt and pepper. 2. In a mixing bowl combine a half block of cream cheese, 1/2 cup of sour cream, half a packet of ranch seasoning, handful of shredded sharp cheddar and a teaspoon of cayenne pepper. 3. Throw that mixture in the baking pan with a half cup of buffalo sauce and combine throughly. 4. Sprinkle crumbled bacon, more sharp cheddar cheese and pickled jalapeños on top. 5. Bake in the oven at 400 degrees for 20 minutes 6. Enjoy, love you #lowcarbrecipe #keto #easyrecipe #comfortfood #buffalochicken #bacon #midwestcooking #nebraskarecipe #spicy #jalapenos #foodporn #comfortfood #newyear #diet #foodhack #healthy #weightloss #meatKeto Pills Review 2020 2020 Edition Truth About Keto Diet PillsYoga Belly Fat-Busters #weightloss #home #exercise #yoga #routines #weightloss #home #exercise #yoga #routines #goals #diet #daily #bodyfit #shorts #youtubeshorts Disclosure - "This video is intended solely for educational purposes. Copyright Disclaimer: Under Section 107 of the Copyright Act 1976, fair use is allowed for criticism, comment, news reporting, teaching, scholarship, and research."Gummies For Weight Lossweightloss Gummies Fatburn HealthManaging pcos & weight loss with metformin + mounjaro #pcos #insulinresistance #weightloss #fokSecret To Big Calves Motivation Legday Fitness Gym WeightlossMy weigh-in recorded from the apple store...A Life Saving Diet The Ketogenic DietStubborn fat-burning workout you can do at home without equipment:👇🏼 1. High Knees – 45 seconds (Full body, cardio). 2. Jump Squats – 12-15 reps (Legs, glutes). 3. Mountain Climbers – 45 seconds (Core, cardio). 4. Push-Up to Shoulder Tap – 12 reps (Upper body, core). 5. Burpees – 10-12 reps (Full body). 6. Bicycle Crunches – 15-20 reps per side (Core). 7. Plank to Toe Touch – 12-15 reps (Core, shoulders). 8. Lunge Jumps – 10 reps per leg (Legs, glutes 9. Side Plank with Hip Dips – 10 dips per side (Obliques). 10. Flutter Kicks – 45 seconds (Lower abs). Repeat 2-3 rounds. Rest for 30-60 seconds between exercises and 2 minutes between rounds. #hustlegauravv #hustlenikita #gym #gymrat #homeworkout #weightloss #viral #fitness #workout #fitwithmahimaa #fatlosstipsDiet Coffee Weight Loss Coffee Javita Burn Control Gourmet Instant Weightloss CoffeeOfficial Website: https://cutt.ly/GOKETO-GUMMIES ✅ Go Keto Gummies - Go Keto Gummies REVIEW -THE TRUTH - GoKeto REALLY WORK? After all, what is GoKeto Gummies and does it really help you to lose weight and lose fat naturally and safely? And the answer is yes, today GoKeto Gummies is helping thousands of people because within its ingredients there are many powerful natural ingredients that help speed up your metabolism, such as chromium green tea extracts and others. many people can't lose weight because their metabolism is too slow and when their metabolism is slow it can't burn energy it can't burn fat and you can't lose weight and that's why this product is helping a lot of people because it makes their metabolism work faster and as your metabolism works faster you will lose weight ok. So it really works, there is something really important that you need to know as well is that you have to be realistic about your treatment as I just said GoKeto Gummies is not a super powerful magic product but it will help you speed up your metabolism and all metabolisms it works in a different way. different and unique way so it may be that you lose a lot of weight in two or three months many people lose more weight after three to six months it will always depend on how your body reacts so if someone tells you you are going to lose 10 kilos in a week this is impossible ok. you will have to test the product and see how your metabolism will react to the ingredients that are in it GoKeto Gummies ok so be realistic about your treatment this is something important and sincere i have to tell you What is the best way to take GoKeto Gummies? Each bottle is made up of 60 gummies made with the finest quality ingredients and according to the makers of this product you can take two gummies every day with a glass of water and they also suggest taking the supplement consistently for a few weeks to get the best results. max out of it. of benefits. What are the side effects? This supplement has no side effects. It contains only natural ingredients, eliminating the risk of allergies, side effects and any other negative consequences of using the gummies. So yes, you can trust this product. There are many people having great results with GoKeto Gummies and you too can have results. 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Allow the tea to cool down before consuming. 3 day meal plan sample Monday: - Breakfast: Fruit smoothie made with mixed berries, spinach, almond milk, and a scoop of protein powder (~250 calories) - Snack: Small mixed fruit bowl with a handful of almonds (~200 calories) - Lunch: Grilled chicken breast salad with mixed greens, cherry tomatoes, cucumber, and balsamic vinaigrette (~350 calories) - Snack: Protein bar (~200 calories) - Dinner: Baked potato topped with grilled chicken breast and a side of steamed broccoli (~400 calories) - Snack: Small mixed fruit bowl with a handful of nuts (~200 calories) Tuesday: - Breakfast: Homemade protein smoothie with almond milk, banana, spinach, and a scoop of protein powder (~250 calories) - Snack: Small mixed fruit bowl with a handful of cashews (~200 calories) - Lunch: Grilled salmon filet with a side of mashed cauliflower and steamed asparagus (~400 calories) - Snack: Rice cake with peanut butter (~150 calories) - Dinner: Baked potato topped with grilled tilapia and a side of roasted Brussels sprouts (~400 calories) - Snack: Small mixed fruit bowl with a handful of pistachios (~200 calories) Wednesday: - Breakfast: Oats topped with sliced strawberries, a drizzle of honey, and a sprinkle of chia seeds (~300 calories) - Snack: Small mixed fruit bowl with a handful of almonds (~200 calories) - Lunch: Grilled chicken breast salad with mixed greens, bell peppers, cherry tomatoes, and lemon vinaigrette (~350 calories) - Snack: Rice cake with peanut butter (~150 calories) - Dinner: Baked potato topped with grilled chicken breast and a side of roasted carrots (~400 calories) - Snack: Small mixed fruit bowl with a handful of nuts (~200 calories)Weight Loss Homemade Pizza Pizza Diet WeightlossWe believe the goal is GLP1 support, NOT GLP1 replacement. 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With Optiplex Keto Gummies, staying in ketosis has never been easier or more delicious. Ingredients in Optiplex Keto Gummies Optiplex Keto Gummies are made with high-quality ingredients that are carefully selected to support your ketosis journey. Some of the key ingredients in these gummies include exogenous ketones, MCT oil, and natural flavors. These ingredients work together to give your body the energy it needs to stay in ketosis and burn fat for fuel. Unlike other keto products on the market, Optiplex Keto Gummies are free from artificial colors, flavors, and preservatives. This means you can feel good about what you’re putting into your body and trust that you’re getting a quality product that will help you achieve your goals. With Optiplex Keto Gummies, you can optimize your ketosis journey and experience the many benefits of the ketogenic diet. Why Choose Optiplex Keto Gummies? Optiplex Keto Gummies are a game-changer for anyone following the ketogenic diet. Not only are they delicious and easy to take, but they also provide your body with the support it needs to stay in ketosis and burn fat for fuel. With Optiplex Keto Gummies, you can overcome common challenges associated with the ketogenic diet and reach your health and fitness goals faster than ever before. Whether you’re a seasoned keto enthusiast or just starting out on your ketosis journey, Optiplex Keto Gummies can help you optimize your results and feel your best. Say goodbye to cravings, energy crashes, and setbacks – and say hello to a happier, healthier you with Optiplex Keto Gummies. Remember, Optiplex Keto Gummies are not a magic solution and should be used in conjunction with a healthy diet and regular exercise. If you’re looking to supercharge your ketosis journey and achieve lasting results, give Optiplex Keto Gummies a try today. Runnick S Dietcom Weight Loss Challenge VlogHey beautiful people!! I was trying to lose 3 kgs in 25 days😂What a joke my darlings I know. But I’ll try again to lose weight and obviously I’ll change my eating habit 😂 Soundtrack: Evergreen by Morgan Kibby https://youtu.be/Nobt2xfJhCg