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In this episode of Explain This, Andy Rogers, PA-C and Bo McGregor, FNP debunk the most common myths arounds GLP-1 medications like Ozempic, Semaglutide, Tirzepatide and Mounjaro.

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"Could This Be Alzheimer’s Game-Changer? $COYA CEO Reveals GLP-1 Breakthroughs" Nature Magazine has recently covered GLP-1 receptor agonists (GLP-1RAs) in depth, particularly in a January 2025 article in Nature Medicine titled "Mapping the effectiveness and risks of GLP-1 receptor agonists." This study analyzed a massive dataset from the U.S. Department of Veterans Affairs, looking at over 215,000 people with diabetes who started GLP-1RAs compared to those on other diabetes meds. The findings are pretty striking for cognitive health: folks taking GLP-1 drugs showed a reduced risk of neurocognitive conditions, including dementia and Alzheimer’s disease. Specifically, the study found a lower incidence of these disorders compared to people on traditional diabetes treatments like sulfonylureas or DPP4 inhibitors. It’s not just a small dip either—the data suggests a meaningful protective effect on the brain. Coya Therapeutics CEO Arun Swaminathan updates the listeners on where ($COYA Impact Stock) is positioned with their treatments concerning the data presented so far and some new initiatives that $COYA feels the science makes the choice easy. Coya's anti-inflammatory therapy, in conjunction with a GLP1 product, could have a more impactful positive response than one of the therapies as a stand-alone. Produced with CyberLink PowerDirector

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The calories mentioned in this short are for 15 min of walking + 15 min of running = 30 min workout.

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