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Today we’re going to talk about something that almost everyone on a GLP-1 journey hits eventually, the weight loss plateau. Thank you for listening to The Peptide Podcast. If you enjoyed the show and want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. It starts like this: you begin a GLP-1 like semaglutide or tirzepatide, and for the first few weeks or months, the weight seems to fall off. You’re eating less, not obsessing over food, and for the first time in a long time, it feels… easy. Then one day, the scale just stops moving. You’re not doing anything different. You’re still taking the meds. Still trying to eat well. Maybe you’re walking more or lifting weights. But suddenly, nothing’s happening—and the frustration kicks in. Sound familiar? Let’s talk about what’s really going on. 1. What Causes the Plateau? First of all, if you’re in this place right now: you didn’t mess up. GLP-1s are incredibly effective at reducing appetite and creating an initial calorie deficit, which is why people lose weight so quickly in the beginning. But your body isn’t just going to let that continue unchecked. It adapts. This is called adaptive thermogenesis—a fancy way of saying your body becomes more efficient. You start burning fewer calories at rest than you did before. Your resting metabolic rate actually drops beyond what you'd expect just from losing weight alone. It’s a survival mechanism. So what worked at the beginning—eating less and moving a bit more—might no longer be enough to keep the scale moving. This is totally normal. 2. Metabolism & Muscle: Why Strength Training Matters Now More Than Ever So now that we know why the plateau happens, let’s talk about things we can do to help us get over it. Something that often gets overlooked but is absolutely critical—especially if you’re on a GLP-1 or in any kind of calorie deficit. Resistance training is not optional. It’s non-negotiable. Here’s why. When you’re losing weight—whether it’s from a medication like semaglutide or just eating in a calorie deficit—your body isn’t just pulling energy from fat. If you’re not careful, it’s also going to break down lean muscle tissue. And the more muscle you lose, the slower your metabolism gets. Why? Because muscle is metabolically active tissue. It burns calories even when you’re doing absolutely nothing. So if you’re not actively sending a signal to your body to keep that muscle, it’ll start to let it go. That’s where resistance training comes in. When you lift weights or do bodyweight exercises—think squats, push-ups, resistance bands, even heavy housework—you’re telling your body: “Hey, I need this muscle. Don’t burn it for fuel.” This is especially important for those on GLP-1s because these meds reduce appetite so significantly that you might not be eating enough protein—or enough calories in general—to maintain muscle without that extra stimulus. So if you’ve hit a plateau or want to prevent one, ask yourself: Am I strength training at least two to three times a week? Am I prioritizing movements that challenge large muscle groups—like legs, glutes, chest, and back? Am I fueling my workouts with enough protein? And let me be really clear, you don’t have to become a gym rat. You don’t have to lift crazy heavy weights. But you do have to move your muscles in a meaningful, consistent way. Protecting your lean mass is one of the best ways to keep your metabolism humming—not just during your weight loss journey, but after it too. Because this isn’t about just losing weight—it’s about building a strong, metabolically healthy body that can maintain that weight loss for life. 3. Mindset Check: The Plateau Is Not a Failure Now, let’s get into the mental side of this journey—because it’s just as important as nutrition, movement, and medication. One of the biggest challenges people face—especially when progress slows—is the mental roller coaster that comes with watching the scale. And I’ll be honest: weighing yourself every single day is not ideal. Here’s why. Your body weight naturally fluctuates. Daily. And those fluctuations have nothing to do with your actual fat loss or long-term progress. Instead, the number on the scale is influenced by things like: Hydration status – If you’re slightly dehydrated, the scale may dip. But if you drank a ton of water the day before or had more salty food, it may go up due to water retention. Glycogen stores – When you eat carbs, your body stores them in your muscles and liver as glycogen, and for every gram of glycogen, your body stores about 3–4 grams of water. 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Vielen Dank für deine Unterstützung! 🙏 Hier ist das Equipment, das ich für meine Workouts nutze: *Wunderschöne, funktionale Sportbekleidung gibt es z.B. hier*: https://winshape.de/jennyschwarz * Ideal für Step-Übungen: * Mein Step (etwas niedriger als das Reebok Original): https://amzn.to/3CI5yf9 * Das Reebok Original Step: https://amzn.to/2MIKfzZ * Blackroll-Produkte: * Blackroll-Ball 8 cm: https://amzn.to/3jy59h9 * Mini Blackroll: https://amzn.to/39ZczWJ * Blackroll: https://amzn.to/2YWp4wA * Weitere Trainingshilfen: * Rutschfeste Matte (normal): https://amzn.to/2MInThZ * meine große Ehrenkind-Matte (180 x 180 cm): https://amzn.to/42GIPdJ * Großer Gymnastikball: https://amzn.to/3r9Ft0c * Airex Balance Pad: https://amzn.to/2N4gDNm * Pilatesball 18 cm: https://amzn.to/39UszKw oder https://amzn.to/3tlNG2s * Theraband: https://amzn.to/3LFGhBR * Langhantel-Set: https://amzn.to/34ASLcN * Hanteln 1,5 kg: https://amzn.to/34Oxk8E Tipp für das perfekte Trainingserlebnis 📺 Am besten schaust du die Videos im Wohnzimmer auf deinem Smart-TV oder über Chromecast/Fire TV Stick an, um das Workout in vollen Zügen zu genießen! 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Orforglipron is the first oral small molecule (non-peptide) glucagon-like peptide-1 (GLP-1) receptor agonist, taken without food and water restrictions, to successfully complete a Phase 3 trial. At 40 weeks, all three doses (3 mg, 12 mg, 36 mg) of orforglipron achieved the primary endpoint of superior A1C reduction. In addition, the 12 mg and 36 mg doses showed clinically meaningful and statistically significant reductions in body weight vs. placebo. In the study, orforglipron had a safety profile similar to the established GLP-1 class, and the most frequently reported adverse events were gastrointestinal-related. 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When prepared with low-carb sweeteners and wholesome ingredients, keto gummies can contain a fraction of the carbohydrates found in traditional gummy candies. They are generally low in calories and sugar, making them suitable for those on a ketogenic diet. Another common inquiry revolves around the effectiveness of keto gummies in supporting weight loss. While they can satisfy cravings and prevent you from relapsing into unhealthy snack choices, moderation is essential. Enjoying them as part of a well-rounded, nutrient-dense diet will support your weight loss goals compared to indulging excessively. Moreover, incorporating other keto-friendly foods ensures a balanced approach to eating. Some may also wonder how long homemade keto gummies last. When stored in the refrigerator, they typically last for about two weeks. To increase longevity, you might explore recipes that use natural preservatives like lemon juice or vinegar. Additionally, consider batch-making gummies to freeze for later enjoyment, allowing you to always have a keto-friendly snack on hand. Ultimately, with knowledge and preparation, keto gummies can become a delightful, guilt-free addition to your healthy lifestyle! Ozempic Is Weight Loss Medicine Karanjohar[SUBSCRIBE TO MY CHANNEL] http://youtube.com/omarisuf [JOIN US ON MY FACEBOOK ARMY] http://www.facebook.com/chefbuff [MY FEMALE WORKOUT CHANNEL!] http://www.youtube.com/sexychefbuff [FOLLOW ME ON TWITTER] http://twitter.com/omarisuf [MY FAT LOSS PROGRAM] http://fatasstobaddass.com/ [MY MASS AND STRENGTH PROGRAM] http://projectbuff.com 1. Avoid Processed Foods If it comes in a box, I don't like it. All the preservatives, sodium, High-fructose corn syrup and trans-fats all conspire to drive them calories straight to your gut. If it has more than 3 ingredients, we don't want it. 2. Reduce sugar intake, refined starches If its not a fruit, we don't want that sugar. We don't want white bread, bagels, pop or pasta. You should make sure all your carb sources got some fibre, too. yams, quinoa, oats, beans and lentils are great sources. 3. Increase Your Fibre Fibre will slow the absorption of carbs into your body. Chronically elevated blood sugar levels are a big contributor to gut fat. Make sure you are getting at least 30 grams daily. More avocados, lentils, beans, flax seed and all your vegetables are great sources. 4. Exercise, the more the better Studies showed the more frequently an individual exercise, the faster they lost visceral fat. Big compound movements in particular are excellent. Between weight lifting and cardio, get minimum 5-7 hours of exercise a week. 5. Do Intense Energy System Work Even when gaining size, a couple cardio sessions 3-4 times per week are a great idea to keep your body efficient with processing food. It won't make you lose muscle but it will prevent you from gaining fat. Stadium runs, wind sprints, prowler pushing, and hill sprints are all excellent examples 6. Get Enough Good Fats Fat don't make you fat. Period. Watch this for the skinny of fat. 7. Avoid Too Much Alcohol At Once Alcohol is a toxin on the body and contains calories that can't really be utilized. When you drink, your liver has to clear that poison, and any other calories being processed go straight to forming adipose tissue. Avoid too many drinks at once. I'm talking over 3-4 drinks at any one time. 8. Eat fruits + veggies high in anti-oxidants You should get at least 5 servings of vegetables a day and at least one serving of fruit. Fruit is the nectar of the Gods. Don't' be a beast in the gym and a bitch in the kitchen. Eat ya damn greens. 9. Decrease Chronically Elevated Cortisol Levels Cortisol is great to wake you up in the morning but chronically elevated levels will wreck your hormonal profile. Poor sleep, stress, inflammatory foods, and your environment can all make your cortisol too high. A great supplement for this is phosphatidylserine which has been shown to lower elevated levels of cortisol. I'll make an in depth video about how to lower cortisol levels http://en.wikipedia.org/wiki/Phosphatidylserine As you can tell. Getting rid of visceral fat is partially AVOIDING certain things and DOING other things. How long results will take is dependent on YOU, how much you have to lose. I gave y ou the solution, now it depends on YOU to carry it out! There are no quick fixes but there are permanent solutions. ^ C.T. Montague and S. O'Rahilly, "The perils of portliness: causes and consequences of visceral adiposity", Diabetes vol 49, pages 883-888 (2000) ^ P.A. Kern, Ranganathan, et al, "Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance", Am J Physiol Endocrinol Metab vol 280 pages E745-E751 (2001), (Abe, T., Sugita, M & Fukunaga T, 1997; Hickey et al, 1997) ^ A. 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