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This Harvard Medical School Continuing Education video examines these key questions: What role do GLP1 receptor agonists (GLP1 RA) play in weight loss? What are the risks and benefits of using GLP1 RA for weight loss? Lee-Shing Chang, MD, an endocrinologist at Brigham and Women’s Hospital, identifies FDA-approved medications for weight loss and explains GLP1 and the role GLP1 receptor agonists play in weight management. Key studies including the SCALE and STEP trials are highlighted and the efficacy of the GLP-1 receptor agonists liraglutide and semaglutide are compared. 00:00 | Introduction 00:37 | Pharmacotherapy for weight management 01:25 | What is GLP1 and what does it do? 02:35 | Clinical trials of liraglutide and semaglutide for weight loss This video was peer reviewed by Dr. Jonathan Salik, TMD, MHPEd, Instructor of Medicine, Massachusetts General Hospital; and Dr. Sugantha Sundar, MD, Assistant Professor of Anesthesia, Beth Israel Deaconess Medical Center, to validate the quality and accuracy of the content. References: Muskiet MHA, Tonneijck L, Smits MM, et al. GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes. Nat Rev Nephrol. 2017;13(10):605-628. doi:10.1038/nrneph.2017.123 Pi-Sunyer X, Astrup A, Fujioka K, et al. A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. N Engl J Med. 2015;373(1):11-22. doi:10.1056/NEJMoa1411892 Wilding JPH, Batterham RL, Calanna S, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021;384(11):989. doi:10.1056/NEJMoa2032183 Rubino DM, Greenway FL, Khalid U, et al. Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial. JAMA. 2022;327(2):138-150. Rubino D, Abrahamsson N, Davies M, et al. Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial. JAMA. 2021;325(14):1414-1425. doi:10.1001/jama.2021.3224 Notice: At this time, the content in this video is not accredited.

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keywords sugar use disorder, emotional triggers, excessive sugar eating, GLP-1 agonists, carnivore diet, self-soothing, recovery journey, sensitivity, borderline foods, self-acceptance summary In this conversation, Dr. Cammy and Mike Collins delve into the complexities of ecessive sugar intake, emotional triggers, and the journey towards recovery. They discuss the challenges of transitioning from a standard diet to a keto or carnivore diet, the impact of emotional sensitivity, and the importance of self-soothing techniques. The conversation emphasizes the need for self-acceptance and the understanding that recovery is a process filled with ups and downs. They also explore dietary options, including GLP-1 agonists, and the role of caffeine and borderline foods in managing cravings and emotional health. takeaways Sugar addiction is often harder to overcome than drug addiction. Emotional triggers play a significant role in binge eating. Self-soothing techniques are crucial in recovery from addiction. The journey of recovery is filled with ups and downs. Sensitivity to emotions can impact addiction recovery. Self-acceptance is key to overcoming food addiction. Caffeine can keep cravings for sugar alive. Borderline foods can trigger binge eating behaviors. It's important to manage emotions rather than just focus on weight loss. Healing from addiction takes time and awareness. titles Breaking Free from Sugar Addiction The Emotional Journey of Recovery Sound Bites "You're not alone in this struggle." "This process is part of the journey." "Healing takes time and awareness." Chapters 00:00 Introduction to Sugar Addiction and Recovery 02:32 Understanding Emotional Triggers and Binge Eating 05:11 Exploring GLP-1 Agonists and Their Implications 08:05 The Impact of Family Dynamics on Addiction 10:38 The Role of Sensitivity in Addiction Recovery 12:59 Navigating the Challenges of Caffeine and Sugar 15:48 Finding Balance: Carnivore Diet and Binge Management 26:41 Understanding Emotional Triggers and Food Addiction 30:42 The Journey of Self-Acceptance and Awareness 35:33 Unpacking Past Behaviors and Their Impact 38:59 Navigating the Path to Self-Love and Healthy Choices 44:23 Identifying Borderline Foods and Their Effects 47:36 Recognizing Different Types of Sugar Users

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Ein gut strukturierter Ernährungsplan ist entscheidend, um erfolgreich abzunehmen. Er sollte individuell auf die Bedürfnisse und Ziele einer Person zugeschnitten sein und eine ausgewogene Mischung aus Proteinen, Kohlenhydraten, gesunden Fetten, Vitaminen und Mineralstoffen enthalten. Durch die richtige Planung kann sichergestellt werden, dass der Körper alle notwendigen Nährstoffe erhält, ohne dabei übermäßige Kalorien zu sich zu nehmen.

Ein Ernährungsplan kann auch dabei helfen, den Überblick über die tägliche Nahrungsaufnahme zu behalten und die Portionsgrößen zu kontrollieren. Indem man im Voraus plant, was man isst, kann man Versuchungen widerstehen und das Risiko von ungesunden Snacks oder Mahlzeiten reduzieren. Ein strukturierter Ernährungsplan kann somit dazu beitragen, die Disziplin aufrechtzuerhalten und langfristig erfolgreich Gewicht zu verlieren.

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Es kann auch hilfreich sein, Unterstützung von einem Ernährungsberater oder Personal Trainer zu suchen, um einen maßgeschneiderten Ernährungsplan zu erstellen. Diese Fachleute können dabei helfen, die individuellen Bedürfnisse und Ziele einer Person zu berücksichtigen und mögliche Herausforderungen zu identifizieren. Indem man sich professionelle Unterstützung holt, erhöht man die Erfolgschancen und kann auf dem Weg zum Abnehmen besser begleitet werden.

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Eine ausgewogene Ernährung ist entscheidend, um erfolgreich abzunehmen und die Gesundheit zu verbessern. Sie sollte eine Vielzahl von Lebensmitteln enthalten, darunter Obst, Gemüse, Vollkornprodukte, mageres Protein und gesunde Fette. Eine ausgewogene Ernährung liefert alle notwendigen Nährstoffe, um den Stoffwechsel anzukurbeln und den Körper mit Energie zu versorgen.

Es ist auch wichtig, auf die Portionsgrößen zu achten und nicht mehr zu essen, als der Körper benötigt. Durch das Bewusstsein über die eigene Nahrungsaufnahme und das Maßhalten bei den Mahlzeiten kann man die Kalorienaufnahme kontrollieren und erfolgreich abnehmen. Eine ausgewogene Ernährung trägt somit dazu bei, das Wohlbefinden zu steigern und das Risiko von Krankheiten zu reduzieren.

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Um das erreichte Gewicht langfristig zu kontrollieren, ist es wichtig, die Ernährungsgewohnheiten langfristig zu ändern und einen gesunden Lebensstil beizubehalten. Regelmäßige Bewegung, ausreichend Schlaf und Stressmanagement sind wichtige Faktoren, um das Gewicht zu halten und die Gesundheit zu unterstützen. Es ist auch empfehlenswert, regelmäßig den Ernährungsplan zu überprüfen und bei Bedarf anzupassen, um weiterhin Erfolge beim Abnehmen zu erzielen.

Indem man sich langfristig auf eine ausgewogene Ernährung und einen aktiven Lebensstil konzentriert, kann man das erreichte Gewicht halten und das Risiko von Jojo-Effekten reduzieren. Es ist wichtig, Geduld und Durchhaltevermögen zu zeigen und sich nicht von Rückschlägen entmutigen zu lassen. Mit der richtigen Einstellung und einem gut strukturierten Ernährungsplan ist es möglich, langfristig erfolgreich Gewicht zu verlieren und die Gesundheit zu verbessern.

Zusammenfassung und häufig gestellte Fragen

Die Erstellung eines gut strukturierten Ernährungsplans ist ein wichtiger Schritt auf dem Weg zum erfolgreichen Abnehmen und zur Verbesserung der Gesundheit. Indem man realistische Ziele setzt, eine ausgewogene Ernährung einhält und regelmäßig den Plan überprüft und anpasst, kann man langfristig erfolgreich Gewicht verlieren. Es ist empfehlenswert, professionelle Unterstützung in Anspruch zu nehmen und den Fokus auf eine nachhaltige Veränderung der Ernährungsgewohnheiten zu legen, um langfristige Erfolge zu erzielen.

Häufig gestellte Fragen:

1. Wie kann ich meinen eigenen Ernährungsplan erstellen?

Um einen individuellen Ernährungsplan zu erstellen, ist es empfehlenswert, realistische Ziele zu setzen, eine ausgewogene Ernährung einzuhalten und professionelle Unterstützung in Anspruch zu nehmen. Es kann auch hilfreich sein, die eigenen Nahrungsgewohnheiten zu überprüfen und mögliche Problemstellen zu identifizieren.

2. Welche Rolle spielt Bewegung beim Abnehmen?

Bewegung spielt eine wichtige Rolle beim Abnehmen, da sie den Stoffwechsel anregt, Kalorien verbrennt und die Muskulatur stärkt. Es ist empfehlenswert, regelmäßig Sport zu treiben und sich ausreichend zu bewegen, um das Gewicht zu reduzieren und die Gesundheit zu fördern.

3. Wie kann ich langfristig erfolgreich Gewicht verlieren?

Um langfristig erfolgreich Gewicht zu verlieren, sollte man auf eine ausgewogene Ernährung, regelmäßige Bewegung und einen gesunden Lebensstil achten. Es ist wichtig, realistische Ziele zu setzen, Geduld zu zeigen und sich nicht von Rückschlägen entmutigen zu lassen.

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Dr. Gil Blander and Ashley Reaver dive into the science behind GLP-1 agonists, a class of drugs originally developed for type 2 diabetes but now widely used for weight management and longevity. They explore how these medications work, their effects on appetite, metabolism, and inflammation, and why they might be a game-changer for cardiovascular health, brain function, and fertility. While promising, they emphasize the importance of long-term research and consulting with medical professionals before considering these treatments. The conversation shifts to the role of wearables in health tracking. Gil shares insights on devices like the Apple Watch, Oura Ring, and Whoop, highlighting their capabilities in tracking sleep, fitness, illness detection, and fall prevention—especially for older adults. They break down how different wearables cater to specific needs and the future of personalized health monitoring. As the science of longevity evolves, Gil and Ashley stress the importance of staying informed, making data-driven decisions, and using technology wisely. Whether through cutting-edge pharmaceuticals or smart wearables, optimizing health is now more accessible than ever. Host-at-a-Glance 💡 Name: Gil Blander  💡What he does: Founder and CSO 💡Company: InsideTracker 💡Noteworthy: Expert in longevity, nutrition, and personalized health optimization 💡 Where to find them: LinkedIn Host-at-a-Glance 💡 Name: Ashley Reaver  💡What she does: Lead Nutrition Scientist 💡Company: InsideTracker 💡Noteworthy: Specializes in metabolism, nutrition, and biomarker-based health strategies 💡 Where to find them: LinkedIn  Episode highlights: [00:00:00] Introduction  [00:02:02] Understanding GLP-1 Hormones [00:04:26] GLP-1 Receptor Agonists: Mechanism and Benefits [00:06:50] Impact of GLP-1 on Weight and Health [00:21:16] Side Effects and Considerations of GLP-1 Agonists [00:26:31] The Future of GLP-1 Agonists [00:34:54] Exploring Wearables for Health [00:36:08] Choosing the Right Wearable [00:40:29] Wearables for Detecting Illness and Falls [00:47:12] Conclusion and Final Thoughts Key Insights GLP-1 Agonists: A Breakthrough for Weight and Metabolic Health GLP-1 agonists, originally developed for type 2 diabetes, have become a game-changer for weight loss, appetite control, and longevity. These drugs mimic natural gut hormones that regulate hunger and insulin secretion, helping people feel full longer and stabilizing blood sugar levels. Studies show that GLP-1 agonists can reduce body weight by up to 25%, a level comparable to bariatric surgery. Beyond weight management, these drugs may lower inflammation, improve cardiovascular health, and even reduce the risk of certain cancers. However, long-term use is likely necessary, as stopping the medication often leads to weight regain. Gil and Ashley emphasize the importance of medical supervision and highlight ongoing research into how GLP-1 impacts cognitive function and fertility. Long-Term Use of GLP-1 Agonists: Training the Body for Better Habits Many wonder if GLP-1 medications are a short-term fix or a lifelong commitment. While the drugs suppress appetite, weight regain is common after stopping treatment. Gil suggests using this period as a training phase—learning to prioritize whole foods, avoid processed meals, and build sustainable habits. He also highlights the importance of exercise, especially strength training, as GLP-1 users risk losing muscle mass along with fat. Regular blood tests and nutrient monitoring are essential, as some users may experience vitamin deficiencies. The hosts caution against taking GLP-1 agonists solely for cosmetic weight loss and emphasize that obesity is a chronic, progressive condition requiring long-term management. This insight reinforces the idea that successful weight loss isn’t just about medication—it’s about lifestyle changes and long-term commitment. Wearables: The Future of Personalized Health Tracking Wearables are reshaping how individuals monitor their health from fitness to disease prevention. Gil and Ashley break down Apple Watch, Oura Ring, and Whoop, each catering to different needs. Apple Watch excels at fall detection and emergency response, making it ideal for older adults. Oura Ring provides early illness detection through temperature and heart rate variability tracking. Whoop is favored by athletes for its detailed recovery insights and sleep monitoring. Wearables aren’t just for data collection—they drive behavior change, encouraging users to improve sleep, exercise, and stress management. With AI-driven health coaching on the rise, the hosts predict that wearables will play a central role in proactive healthcare and longevity strategies. Longevity by Design is produced by InsideTracker, your data-driven wellness guide for optimizing your healthspan. For a limited time, visit https://hubs.li/Q021Z4gp0 for 20% off any InsideTracker plan.