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As a mild mitochondrial poison, metformin carries a variety of downsides. Taking it may have about a 1-in-67,000 chance of killing you every year. This is the fourth video in a five-part series. If you missed any so far, see: • Naturally Boosting AMPK with Caloric Restriction for Life Extension (https://nutritionfacts.org/video/naturally-boosting-ampk-with-caloric-restriction-for-life-extension) • Naturally Boosting AMPK with Exercise for Life Extension (https://nutritionfacts.org/video/naturally-boosting-ampk-with-exercise-for-life-extension) • Does Metformin Work as a Life-Extension Drug? (https://nutritionfacts.org/video/does-metformin-work-as-a-life-extension-drug ) And stay tuned for The TAME Trial: Targeting Aging with Metformin (https://nutritionfacts.org/video/the-tame-trial-targeting-aging-with-metformin). AMPK is one of the anti-aging pathways I highlight in my longevity book, How Not to Age (https://nutritionfacts.org/book/how-not-to-age/), available in print, e-book, and audio. (All proceeds I receive from the book are donated directly to charity.) New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/. Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/side-effects-of-metformin-as-a-life-extension-drug and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/video/side-effects-of-metformin-as-a-life-extension-drug. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution! -Michael Greger, MD FACLM Captions for this video are available in several languages; you can find yours in the video settings. View important information about our translated resources: https://nutritionfacts.org/translations-info/ https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Books: https://nutritionfacts.org/books • Shop: https://drgreger.org • Facebook: https://www.facebook.com/NutritionFacts.org • Twitter: https://twitter.com/nutrition_facts • Instagram: https://www.instagram.com/nutrition_facts_org

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February is Cancer Awareness month! Today, Dr Berger discusses the new study that demonstrates decreased risk for 10 of the 13 obesity-related cancers with the use of GLP1-type medications (such as Ozempic, Wegovy, Mounjaro, and Zepbound). To learn more about our concierge medicine program which includes a comprehensive weight management program, led by a physician board certified in obesity medicine, please visit: www.northeastmedicalpractice.com Northeast Medical Practice 17 Maple Drive, Suite 5 Great Neck, NY 11021 516-604-3418 #northeastmedicalpractice #obesitytreatment #weightmanagement #wegovyweightloss #ozempicweightloss #zepboundweightloss #mounjaroweightloss #MediterraneanDiet #ketodiet #vegandiets #greatneckny

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Are GLP-1 weight loss drugs a medical breakthrough or a ticking time bomb? The debate is louder than ever—hailed by some as miracle cures, dismissed by others as dangerous shortcuts. Cutting through the noise is renowned Delhi-based endocrinologist Dr. Ambrish Mithal, whose new book "The Weight Loss Revolution" separates fact from fiction. In this exclusive conversation with Sneha Mordani, he answers the big questions: Who should use these drugs? Are they safe? And what does the science really say? #Booked #SnehaMordani #DrAmbrishMithal #weightloss #GLP1 #Ozempic #Mounjaro #Wegovy #indiatoday #itwebvideos Subscribe to India Today for NEW VIDEOS EVERY DAY and make sure to enable Push Notifications so you'll never miss a new video. All you need to do is PRESS THE BELL ICON next to the Subscribe button! India Today TV is India's leading English News Channel. India Today YouTube channel offers latest news videos on Politics, Business, Cricket, Bollywood, Lifestyle, Auto, Technology, Travel, Entertainment and a lot more. Stay tuned for latest updates and in-depth analysis of news from India and around the world! WhatsApp Channel: https://whatsapp.com/channel/0029Va2AnW3JENxxg7OuJv00 Download App: https://indiatoday.link/wHaj Follow us: Official website: https://www.indiatoday.in/ Twitter: https://twitter.com/IndiaToday Facebook: https://www.facebook.com/IndiaToday

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The ketogenic diet has gained immense popularity in recent years for its potential health benefits, including weight loss and improved energy levels. As more and more people are turning to the keto diet, the demand for keto-friendly supplements has also increased. One of the most popular keto supplements on the market today is keto gummies. These convenient and delicious treats are a great way to support your keto lifestyle while satisfying your sweet tooth.

Where to Buy Keto Gummies

When it comes to buying keto gummies, there are several options available. You can find them at your local health food store, online retailers, or even make your own at home. However, not all keto gummies are created equal, so it’s important to do your research and choose high-quality products that will support your health goals. Here are some tips to help you find the best keto gummies for your needs.

Factors to Consider When Buying Keto Gummies

1. Ingredients: Look for keto gummies that are made with clean, high-quality ingredients. Avoid products that contain added sugars, artificial colors, or flavors. Opt for gummies that are sweetened with natural sweeteners like stevia or monk fruit.

2. Net Carbs: Since the ketogenic diet focuses on limiting carb intake, it’s important to choose keto gummies that are low in net carbs. Make sure to check the nutrition label and choose gummies that fit within your daily carb allowance.

3. Quality: Consider the brand reputation and quality of the keto gummies you’re buying. Look for products that are manufactured in a GMP-certified facility and have positive customer reviews.

Benefits of Keto Gummies

Keto gummies offer a convenient and tasty way to support your ketogenic lifestyle. They can help curb cravings for sugary treats while providing a dose of essential nutrients. Additionally, some keto gummies are formulated with ingredients like MCT oil or collagen, which can further support your health and wellness goals.

Furthermore, keto gummies are easy to take on the go, making them a perfect snack or treat for busy individuals. You can keep a pack of keto gummies in your bag or desk drawer for a quick and satisfying pick-me-up whenever you need it.

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There’s a dangerous myth floating around that people on GLP-1 medications like semaglutide or tirzepatide are just sitting around doing nothing while the weight magically falls off. As a woman over 50, I’m here to tell you — that couldn’t be further from the truth. In this video, I break down the realities of using GLP-1s: The side effects — from nausea to the rare but serious risks like gallstones and pancreatitis. The science behind weight set point theory and why our bodies resist weight loss. The unique challenges women face after 40, especially post-menopause, when blood sugar regulation becomes harder and the risks of heart disease and stroke go up. If you’ve ever felt shame for getting help… if you’ve been judged for using medication… or if you simply want a real, evidence-based perspective — this video is for you. You are not a failure. You are not weak. You’re choosing health. And that’s powerful. Let’s talk in the comments—your journey matters. #GLP1 #Semaglutide #Tirzepatide #WomensHealthOver40 #GLP1Journey #MenopauseWeightGain #SetPointTheory #WeightLossSupport #HealthNotHype Get my GLP-1 Checklist at https://aminata.store/shop/219a364c-e803-42e9-82de-7173179223f0

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Understanding Macronutrients and Their Role in Weight Loss

In the quest for weight loss, understanding macronutrients is crucial. Macronutrients, often referred to as macros, comprise three primary components: carbohydrates, proteins, and fats. Each of these macros plays a distinct role in the body’s functioning, and knowing how to balance them can be the key to successful weight management. Carbohydrates provide energy, proteins are essential for building and repairing tissues, and fats support cell growth and hormone production. By calculating these macros appropriately, individuals aiming to lose weight can create a diet plan that not only promotes fat loss but also sustains energy levels and enhances overall health.

The journey of weight loss is not merely about cutting calories; it’s essential to focus on the quality and proportion of the foods consumed. For instance, it is not enough to merely reduce calorie intake; one should also consider what those calories consist of. By understanding the significance of each macronutrient, one can make informed food choices that foster a sense of fullness and satisfaction while adhering to a calorie deficit. This approach can mitigate feelings of deprivation and promote long-term adherence to dietary changes.

Furthermore, tracking macros serves as a personalized approach to dieting. Each individual’s body composition, activity level, and metabolic rate differ, meaning that a one-size-fits-all plan is often ineffective. By calculating their unique macro needs based on specific goals, individuals can fine-tune their nutrition to optimize performance in workouts and daily activities, making their journey not only about losing weight but about achieving a healthier, more active lifestyle. As we delve into the steps to calculate macros specifically for weight loss, a clearer picture of how to tailor one’s diet will emerge, making the process more accessible and effective.

Step One: Determining Your Caloric Needs

The first step in calculating macros for weight loss involves determining your daily caloric needs. This process generally starts by calculating the Total Daily Energy Expenditure (TDEE), which considers your Basal Metabolic Rate (BMR) and physical activity level. Your BMR represents the number of calories your body needs to maintain basic physiological functions at rest, such as breathing, circulation, and cell production. Various online calculators can assist you in determining your BMR by incorporating factors such as age, height, weight, and gender.

Once you have your BMR, the next step is to multiply this figure by an activity factor that corresponds to your lifestyle. Activity levels are categorized typically as sedentary, lightly active, moderately active, very active, or super active. Each category bears a different multiplier that reflects the additional calories burned through physical activity. For example, a sedentary person might multiply their BMR by 1.2, while an extremely active individual may use a multiplier of up to 1.9. This calculation will yield your TDEE, which is the number of calories needed to maintain your current weight.

<pAfter calculating your TDEE, you can establish a caloric deficit, which is essential for weight loss. This is typically achieved by consuming fewer calories than your TDEE. A safe recommendation for weight loss is to aim for a deficit of 500 to 1000 calories per day, depending on individual factors and weight loss goals. This deficit can facilitate a steady weight loss of about 1-2 pounds per week, a rate considered safe and sustainable. With your caloric needs established, you are now ready to allocate those calories toward specific macronutrient targets that will form the foundation of your weight loss plan.

Step Two: Macro Distribution Based on Goals

Determining your macro distribution is the next crucial step after calculating your caloric needs. Generally, for weight loss, a common macro distribution is around 40% carbohydrates, 30% protein, and 30% fat. However, these percentages can be adjusted based on personal preferences, dietary restrictions, and lifestyle choices. Protein, for example, plays a significant role in muscle preservation during weight loss, which is why increasing protein intake can be beneficial for those looking to retain lean muscle mass while shedding fat.

Carbohydrates are vital as they serve as the main energy source for the body, especially during workouts. A too-low carbohydrate intake can lead to fatigue, making it more difficult to stick with regular exercise routines, which is essential for overall weight loss and health. Therefore, finding a balanced approach that allows for enough carbs to fuel activities while still promoting fat loss is ideal.

Fats are often misunderstood but are necessary for various bodily functions, including hormone production and nutrient absorption. Healthy fats should be prioritized, such as those found in avocados, nuts, seeds, and fatty fish. Striking the right balance among these macronutrients is essential for creating a diet that is enjoyable and sustainable. Once the appropriate ratios are established, you can proceed to calculate specific macro targets based on your total caloric intake, ensuring each meal is nutritionally balanced and supports both weight loss and overall well-being.

Step Three: Tracking and Adjusting Your Macros

Once you have established your macro distribution, the next step is meticulously tracking your food intake. This can be achieved through various methods, including food journals, mobile applications, or online databases. The goal here is to maintain awareness of what you are consuming, how it aligns with your calculated macros, and how it affects your weight loss journey. Tracking enables you to identify patterns in your eating habits and make necessary adjustments, enhancing the precision of your dietary approach.

Depending on the outcomes you observe over time, you may need to adjust your macro intake. If you find that you are not losing weight as expected after a few weeks of following your initial plan, it could be beneficial to reassess your portion sizes or tweak your macro ratios. For example, increasing protein or reducing carbohydrate intake might spur additional fat loss without significantly impacting energy levels if approached properly.

Additionally, consider the importance of meal timing and nutrient timing around workouts. Consuming carbohydrates before and protein after exercise can help fuel performance and aid recovery, respectively. By actively engaging with your dietary choices and responding to how your body reacts, you can create a dynamic nutrition plan that accommodates changes in weight, energy levels, and overall well-being. The process is not static; it requires continuous evaluation and flexibility to optimize effectiveness.

Integrating Exercise with Macro Calculations

While calculating macros is a vital aspect of weight loss, it should be complemented by a well-rounded exercise program. Exercise not only assists in burning calories but also promotes muscle retention, contributing to a higher metabolic rate. Incorporating both cardiovascular and strength training exercises is ideal for creating an effective weight loss strategy. Cardiovascular activities, like running or cycling, can help in burning a significant number of calories and improving heart health, while strength training is essential for muscle preservation and can boost post-workout calorie expenditure due to the afterburn effect.

When designing an exercise regimen, pay attention to how it aligns with your caloric and macronutrient goals. For instance, if your workout intensity is high, you might want to ensure adequate carbohydrate intake beforehand to provide enough energy. Conversely, post-workout nutrition should include both protein and carbohydrates to facilitate muscle recovery. Finding this balance between macro intake and exercise can enhance performance and results.

Moreover, consistency in both diet and exercise yields the best outcomes over time. The journey of weight loss is often met with challenges and fluctuations; therefore, maintaining a routine and being adaptable is crucial for long-term success. Besides enhancing physical health, exercise can also improve psychological well-being, helping to foster a positive mindset toward food and body image. Ultimately, integrating exercise with calculated macros can create a holistic approach to weight loss that not only addresses physical appearance but overall health and fitness.

Common Questions and Key Takeaways

Many individuals seeking to calculate macros for weight loss often ask about the timeframe in which they can expect to see results. Generally, a realistic expectation is to aim for 1-2 pounds of weight loss per week. However, individual factors such as initial weight, calorie intake, metabolic rate, and adherence to the plan can influence this process. It is critical to focus on consistency rather than immediate changes to foster long-term success.

Another common query revolves around the necessity of precise macro counting. While accuracy can provide a structured approach to dieting, it is equally important to listen to your body and pay attention to hunger cues. If a strict counting approach feels overwhelming or leads to stress, consider a more intuitive eating approach where the focus is on the quality of foods consumed rather than the exact quantities.

Finally, individuals often inquire about the supplements needed for successful weight loss. While whole foods remain the cornerstone of any weight loss diet, certain supplements can help support specific goals, such as protein powders to meet protein needs. However, it is essential to remember that supplements should not replace a balanced diet but can serve as an effective addition when used properly. In conclusion, understanding and calculating macros for weight loss can serve as a powerful tool in creating a sustainable and effective weight loss strategy, promoting better health outcomes in the long run.

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