Transcript Exploring Care Gold Coast Keto Com For Keto ResourcesThe incidence of Type Two Diabetes has doubled in the U.S. over the past decade. Excess weight suppresses the body's ability to use insulin. So, the best chance to slow the trend is to get more Americans serious about losing weight. Mayo Clinic has a book that can give you a fighting chance.Day 68 Carnivore Food Keto Diet Pizza Pork Foodie Fyp Foryou Shorts ExplorepageClick Here to Subscribe: http://Bit.ly/ThomasVid Get MY groceries at MY price with Thrive Market: http://ThriveMarket.com/Thomas My Website: http://ThomasDeLauer.com Burn Fat Faster | How to Enter 'Fat-Burning Mode' Quicker (Pre-Fasting Strategy) Study - American Journal of Physiology: Assessed the impact of the macronutrient content of a meal on the postprandial leptin response. 22 young healthy subjects (11 men and 11 women) were given, in a randomized order, an isoenergetic meal [carbohydrate (81%) or fat (79%)] or remained fasting. In both genders, leptin response was higher after the carbohydrate meal than after the fat meal and while fasting. In conclusion, a carbohydrate meal induces higher postprandial leptin levels than an isoenergetic fat meal. https://www.ncbi.nlm.nih.gov/pubmed/10567012 So we know that carbs will increase levels of leptin. However, the following study found that leptin levels need to be low in order for fat burning to take place. So trying to spike your leptin right before a fast could be counterproductive. Leptin & Fat Burning: To keep the human brain supplied with energy when food was scarce, mammals evolved the ability to switch from burning carbohydrates to burning fat in order to preserve skeletal muscle that would otherwise be metabolized and converted to glucose. Scientists long believed that the transition to fat metabolism was instigated solely by a drop in insulin. But a new study identified leptin as a key mediator - during starvation, plasma leptin levels fall, activating a pathway that promotes the breakdown of fat and mediates this critical shift from glucose to fat metabolism. While a drop in insulin also occurs, a decrease in leptin is also necessary for this process to happen. Study Summation: Researchers investigated the rate of carbohydrate and fat metabolism as rats went from a fed to a fasted state. The researchers observed that as the rats fasted, leptin levels decreased and activated a pathway that led to fat burning rather than carb burning. During fasting, the rats' use of stored glucose went down and sugar levels decreased as a result. In turn, levels of insulin and leptin decreased - the rats' bodies then broke down body fat to be turned into ketones for energy. Study – Cell: Researchers had rats fast for 48 hours - plasma non-esterified fatty acid (NEFA), glycerol, and bHB (β-OHB) concentrations increased progressively throughout the fast. Unsurprisingly, the reduction in plasma glucose concentrations that occurs as a fast progresses was accompanied by reductions in plasma insulin concentrations and increases in plasma glucagon concentrations. However, they also found that plasma leptin concentrations decreased by 80% between fed and 48-hr fasted rats. Next researchers specifically investigated the impact of reductions in net hepatic glycogenolysis on rates of endogenous glucose production, plasma leptin concentrations, and activation of the HPA axis. They treated post-absorptive rats fasted for 8, 16, and 48 hour with a small molecule inhibitor of glycogen phosphorylase, which resulted in reductions in plasma glucose and insulin concentrations. This was done as it’s consistent with the negligible contributions that hepatic glycogenolysis would be expected to have on plasma glucose concentrations in the glycogen-depleted state (during prolonged fasting.) Interestingly, the reductions in plasma glucose and insulin concentrations in fasted rats treated with the glycogen phosphorylase inhibitor were associated with reductions in plasma leptin concentrations and increases in HPA axis activity, as reflected by increases in plasma corticosterone and ACTH concentrations in these groups. The researchers next infused rats fasted for 48 hours with leptin and found: Increased leptin levels resulted in the suppression of plasma NEFA, glycerol, β-OHB, and lactate concentrations - suppressed HPA axis activity and plasma corticosterone levels as well. Leptin & Fat Burning: Leptin - corticotropin-releasing hormone (CRH), adrenocorticotropic hormone (ACTH), and corticosterone (cortisol in humans) concentrations. Corticotrophin-releasing hormone is secreted by the paraventricular nucleus of the hypothalamus - Corticotrophin-releasing hormone is given this name because it causes release of adrenocorticotropic hormone from the pituitary gland. Adrenocorticotropic hormone, in turn, travels in the bloodstream to the adrenal glands, where it causes the secretion of the stress hormones. Resources: 1) https://www.diabetes.co.uk/news/2018/jan/drop-in-both-insulin-and-leptin-needed-for-fat-burning-to-occur-90969878.html 2) https://www.cell.com/cell/fulltext/S0092-8674(17)31443-5 3) https://www.ncbi.nlm.nih.gov/pubmed/29307489 4) https://www.ncbi.nlm.nih.gov/pubmed/8717038/ 5) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430504/Ikaria Juice Your New Goto Drink For Weight Loss Success Discovering Shark Tank Weight Loss Gummies In recent years, weight loss solutions have become a booming industry, with consumers inundated with options ranging from diet plans to exercise regimes. 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For Shark Tank Weight Loss Gummies, a blend of natural components has been carefully chosen to optimize weight management. One of the primary ingredients is apple cider vinegar, renowned for its ability to support weight loss by enhancing metabolic rates and promoting the feeling of fullness. Many users report that incorporating apple cider vinegar into their diets has helped curb cravings and reduce the intake of excess calories. Another notable ingredient is Garcinia Cambogia, a fruit extract celebrated for its potential to inhibit fat storage. Research suggests that this ingredient may increase serotonin levels in the brain, which helps regulate mood and appetite. When combined with other weight loss strategies, it can significantly contribute to reducing body fat and improving overall wellbeing. Additionally, the gummies harness other botanical extracts that are believed to aid digestion and detoxification, further supporting the weight loss process. It’s essential for consumers to understand that while these ingredients have shown promise in clinical studies, individual results may vary. Factors such as metabolic rates, lifestyle habits, and diet will affect how each person responds to these gummies. Therefore, while they can serve as a helpful tool in one’s weight loss arsenal, they should not be viewed as a magical quick fix. Instead, users are encouraged to consider them as part of a broader health approach, where diet, exercise, and psychological well-being converge to create sustainable change. User Experiences: True Stories from Real People To gain deeper insights into the effectiveness of Shark Tank Weight Loss Gummies, we took the time to collect and analyze user experiences. For many, the gummies’ taste was a pleasant surprise. Unlike traditional supplements that can be hard to swallow, the gummies provide a palatable option that feels more like a treat than a chore. Consumers appreciated the ease of integrating them into their daily routines, with many mentioning they would take them alongside breakfast or as a mid-afternoon snack, which made weight loss feel slightly less cumbersome. Moreover, the shared success stories have fueled interest in these gummies. Some users reported losing significant amounts of weight over a few months, attributing their success to the combination of the gummies alongside a cleaner diet and consistent exercise. These testimonials often include exciting before-and-after photos, showcasing their transformation and motivating other users to try the product. However, as inspiring as these stories may be, they also underline the need for realistic expectations, reminding potential buyers that each body is unique and that results can differ widely. <pWhile many users experienced positive outcomes, it's worth noting that some individuals reported minimal to no weight loss despite consistent use. 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Additionally, the blend of weight loss ingredients can offer a multifaceted approach to tackling weight gain, improving appetite control while potentially enhancing metabolism. However, there are some cons that users should be aware of. The enthusiasm around gummies might lead to over-reliance on them rather than incorporating a balanced diet and exercise regimen. It’s essential to underscore that weight loss supplements, including gummies, should complement a healthy lifestyle rather than act as a standalone solution. Moreover, potential consumers should be cautious about added sugars and calories, which can sometimes negate weight loss efforts if not monitored properly. Another consideration is the financial aspect. Depending on the brand and size of the gummy container, the cost can add up over time. While they may seem relatively affordable compared to other weight loss programs, individuals should evaluate whether the investment aligns with their overall budget and expected results. Overall, weighing the pros and cons is critical in making an informed decision that best meets individual health goals. Addressing Common Queries: FAQs on Shark Tank Weight Loss Gummies As the popularity of Shark Tank Weight Loss Gummies surges, numerous questions arise concerning their use, effects, and overall safety. One common question is related to the recommended dosage. Most manufacturers suggest taking a specific number of gummies daily, and it is crucial for users to adhere to these guidelines to avoid any adverse effects. Exceeding the recommended dosage may not only lead to gastrointestinal issues but also increase the calorie intake through the added sugars present in the gummies. Another frequently asked question centers on the duration of use before one can expect to see results. The timeline for weight loss can vary significantly from person to person, affected by various factors such as individual metabolism, diet, exercise routine, and consistency in using the product. Generally, users should aim for at least a month of consistent use before assessing the efficacy of the gummies, as weight loss is often gradual and not immediate. Lastly, safety is a paramount concern for many consumers. It’s essential to note that while many ingredients in these gummies are natural, individuals with certain health conditions or those taking medications should consult with a healthcare professional before starting any new supplement. Awareness of potential allergies or interactiveness with medications can guide users in their decision-making process, allowing for a safer approach to weight management. 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As we discuss the science of setting realistic goals and sticking to them, a surprising conversation around Ozempic and TRT unfolds. 🎧 Stay tuned to find out: ➡︎ How to create habit loops and why goals should be tailored to small consistent wins ➡︎ Why Mike thinks everyone should be taking Ozempic and weight-loss injections ➡ Whether rising beauty stands are really the problem they’re made out to be ➡︎ What’s going on with the rise in TRT use ➡︎ How we have billionaires to thank for testing out the supplements of tomorrow 📕 Chapters 0:00 Intro 1:16 The science of habit building for the New Year 6:07 Making goals as easy as possible 10:57 Using weight loss injections for habit forming 15:24 Are the risks of Ozempic worth it if you’re not overweight? 21:46 Should we fear taking Ozempic for life? 30:30 The casual rise of TRT 39:04 Body dysmorphia and rising beauty standards 44:40 Bryan Johnson and anti-ageing influencers 📱 Connect with me: TikTok: https://www.instagram.com/drkaranrajan Instagram: https://www.tiktok.com/@dr.karanr 📱 Connect with Mike: YouTube: https://www.youtube.com/@RenaissancePeriodization Instagram: https://www.instagram.com/drmikeisraetel/ 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe 🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 🎙️ An OG Podcasts production.Weight Loss Remedy By This Beautifull Tip Losing Weight Pcos Facial Hair Remedy When it comes to weight loss, many people are constantly looking for new and effective ways to shed those extra pounds. 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Mifflin St Jeor formula BMR (men) = 10 X weight (in kg) + 6.25 X height (in cm) - 5 x age (in years) + 5 BMR (women) = 10 X weight (in kg) + 6.25 X height (in cm) - 5 X age (in years) - 161 OR you can use an online link ✅Factor in Activity Level: Once you have your BMR, you must account for your activity level to determine your total daily energy expenditure (TDEE). Multiply your BMR by an activity factor that represents your typical level of physical activity. ✅Set Your Weight Loss Goal: Determine how much weight you want to lose and the timeframe in which you want to achieve it. Remember that a safe weight loss rate is typically 0.5 to 2 pounds per week. ✅Calculate Your Caloric Intake: To create a calorie deficit, subtract a certain number of calories from your TDEE. A common recommendation is to aim for a deficit of 300 - 500 calories per day. ✅Monitor Progress and Adjust as Needed: Track your food intake and monitor your weight regularly to assess your progress. 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