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Still University: Doctorate In Health Science Program, Adjunct Professor at Nova Southeastern University PhD and DrOT in Occupational Therapy Programs, and Adjunct Professor at Liberty University Department of Health Sciences. Dr. Melanie Tidman is also a Certified Metabolic Health Practitioner, Director of Clinical Research: Colorado Parkinson Foundation, and Chair of the Society of Metabolic Health Practitioners Research Academy. *Links & Contact details: Colorado Parkinson Foundation: co-parkinson.org Research Study Recruitment Email: [email protected] Personal Email: [email protected] *Links to Tidman Published Research Articles Tidman, M. M., White, D., & White, T. (2022). Effects of an Low carbohydrate/healthy fat/ketogenic Diet On Biomarkers of Health and symptoms, Anxiety and Depression in Parkinson’s Disease: A Pilot Study. Neurodegenerative Disease Management, 12(2), 57–66. https://doi.org/10.2217/nmt-2021-0033 https://www.tandfonline.com/doi/full/10.2217/nmt-2021-0033 Tidman MM, White DR, White TA. Impact of a keto diet on symptoms of Parkinson's disease, biomarkers, depression, anxiety and quality of life: a longitudinal study. Neurodegener Dis Manag. 2024 Jun 13:1-14. doi: 10.1080/17582024.2024.2352394. Epub ahead of print. PMID: 38869924. https://www.tandfonline.com/doi/full/10.1080/17582024.2024.2352394 Tidman M. Effects of a Ketogenic Diet on Symptoms, Biomarkers, Depression, and Anxiety in Parkinson's Disease: A Case Study. Cureus. 2022 Mar 31;14(3):e23684. doi: 10.7759/cureus.23684. PMID: 35505754; PMCID: PMC9055978. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055978/ The ketogenic diet and MetSyn in Parkinson’s disease – Symptoms, biomarkers, depression and anxiety: A case study Melanie M. Tidman Journal of Metabolic Health | Vol 7, No 1 | a93 | DOI: https://doi.org/10.4102/jmh.v7i1.93 | © 2024 Melanie M. Tidman | This work is licensed under CC Attribution 4.0 Submitted: 22 November 2023 | Published: 30 April 2024 https://journalofmetabolichealth.org/index.php/jmh/article/view/93/324 Nayiri Mississian, the host of @LowCarbandFasting , is a certified nutrition coach and accredited Metabolic Health Practitioner, researcher, and blogger. Nayiri has had type1 diabetes since 1978, doing intermittent fasting since 2000, eating low carb since 2015, strength training since 2018, extended fasting since 2021 and eating a ketovore/carnivore diet since 2022 (after 30 years of vegetarianism). Nayiri's bio https://lowcarbandfasting.com/about-me Nayiri is also the founding director of a translation company https://ntsprofessionaltranslations.com/ ***Join our community! 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Decreasing Intestinal Absorption of Glucose**: It may also reduce the absorption of glucose from the gastrointestinal tract. Indications Metformin is indicated for: Type 2 Diabetes Mellitus**: It is used to improve glycemic control in adults and children (larger than & equal to 10 years), typically in conjunction with diet and exercise. Polycystic Ovary Syndrome (PCOS)**: Off-label, it is sometimes used to manage symptoms related to insulin resistance in women with PCOS. Dosage and Administration Formulations**: Metformin is available in immediate-release and extended-release formulations. Dosing**: The initial dose is usually low, gradually increased based on tolerance and glycemic control. The maximum dose typically does not exceed 2,000-2,500 mg per day, depending on the formulation. Side Effects Common side effects include: Gastrointestinal issues: Nausea, vomiting, diarrhea, abdominal discomfort, and flatulence (often transient). Lactic acidosis: A rare but serious side effect, particularly in individuals with renal impairment or contraindicating conditions. Contraindications Metformin is contraindicated in: Severe renal impairment (eGFR less than 30 mL/min) Acute or chronic metabolic acidosis, including diabetic ketoacidosis Hypersensitivity to metformin Cautions Renal Function Monitoring**: Kidney function should be assessed before starting therapy and regularly monitored during treatment. Use in Specific Populations**: Caution is advised in patients with liver disease, heart failure, or those undergoing procedures involving contrast media, as these can increase the risk of lactic acidosis. Benefits Beyond Glycemic Control Metformin has additional benefits, including: Weight Management** It is generally weight-neutral or may even promote modest weight loss, making it suitable for overweight individuals with type 2 diabetes. Cardiovascular Benefits**: Some studies suggest that metformin may have cardiovascular protective effects. Conclusion Metformin is a cornerstone in the management of type 2 diabetes, known for its efficacy in lowering blood sugar levels, safety profile, and additional health benefits. As with any medication, it should be prescribed and monitored by a healthcare professional, ensuring that patients receive the most appropriate and effective treatment for their condition. Regular follow-up and lifestyle modifications (diet and exercise) are essential components of diabetes management alongside metformin therapy.Best Keto Keto Gummies 2024 Weight Loss Amazon Are you looking for a superior formula to enhance your keto diet and boost ketosis? Look no further than Enhanced Keto Gummies! These delicious gummies are specially formulated to help you reach and maintain ketosis more effectively, making it easier for you to burn fat and lose weight. 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