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More test are being done, leading consumers into a retail environment where the potency of various plant compounds, known as cannabinoids, are represented in percentages. T-H-Ca and T-H-C are the two cannabinoids most directly relating to the ‘high’ users receive. The macroeconomic inertia behind this emerging industry has forced state and federal government agencies and private research firms, among others, to invest firmly in research of the plant, resulting in solid evidence cannabinoids, the various plant compounds producing the varied biological effects cannabis is known for, can have very different effects on the mind and body of humans and animals. One analysis of the differences by Kate Welch, a doctoral recipient and pharmacist, suggest both THCa and THC interact with the immune and nervous system, as well as various parts of the brain, yet the mechanism or route THCa and THC use to produce the biological effects is incredibly different - sometimes. So…. What does it means to convert THCa to THC? Expressing the differences between the two plant compounds can be done by examining the two cannabinoids at the molecular level. THCa is the carboxylic acid form of THC. With regard to THCa, a carboxylic acid describes the molecular structure including a carbon and oxygen molecule. Under normal circumstances, this prevents the psychoactive THC from being readily available. THCa, much like both CBDa and CBD, produces no psychoactive ‘high’ or related euphoria. The process of removing the carbon and oxygen molecules is done simply by adding heat. this is why eating raw marijuana will not get you stoned, but smoking or otherwise heating it will. It is also important to note laboratory labels on medical or recreational cannabis usually lists both THCa and THC concentrations. If the THCa is testing at 18% and the THC is testing at 1.5%, it may be easily assumed the product - once activated by heat - will be 19.5% THC. This is inaccurate. THCa percentages must be multiplied by the molecular mass of THC before being translated into final THC potential. Interestingly, the analysis released by Kate Welch the pharmacist, suggests THCa can produce at least two clinically significant outcomes more effectively than THC can. THe First being that -- THCa and THC can both provide anti-nausea and anti-vomiting effects, yet research suggests THC is less potent than THCa. In rat studies, the effect of THCa on nausea and vomiting is described as ‘considerable’ and was shown to inhibit these effects by activating serotonin receptors. #2... THCa is more effective than THC at managing inflammation, pain THCa and THC both have clinical potential as an anti-inflammatory and pain reliever, having even been shown to engage similar biological pathways to achieve this effect as ibuprofen or aspirin. Additionally, THCa may work better than THC as a neuroprotective In animal studies. research on the cannabinoids THCa and THC, has suggested the cannabinoid may have a neuroprotective effect.. What That means is cells, rather than degenerating, are encouraged to continue along healthfully. In so doing, this slows the rate an illness such as Parkinson’s disease can radicalize cells. Individuals with neurodegenerative diseases such as Parkinson's have been seeking beyond the realm of traditional western medicine and turning to medical marijuana for their condition, which currently has no cure. Remember, Live Higher!Ashwagandha Gummies For Calm Better Sleep Cortisol CortisolimbalanceWater Based Extraction of Cannabis Professor DeBacco Two Main Water Based Extraction Methods Both use a solvent-free concentrate which customers are often looking for. Cold Water Hot Water Cold Water Extraction 1. Water extraction utilizes a solvent-less method of extraction that submerges finely chopped cannabis plant material in freezing water. 2. The plant is stirred in the cold water causing the trichomes to separate from the plant. 3. Once the trichomes fall off of the plant, it will pass through a series of screens. The end result is a product that has 50% to 70% THC levels. Hot Water Extraction Pressurized hot water offers the advantage of being a safer alternative to other extraction methods. Protocols developed to select against THC. The optimal conditions to extract more CBD, CBC, and CBG than THC and CBN were set at 150 °C, 160 °C, and 45 minutes as extraction temperature, the temperature at collector vessel, and the extraction time, respectively. Description of Pressurized Hot Water Method The desired sample is placed in the cell for extraction The cell is then heated to a predetermined temperature The system is then filled with water and pressurized The sample is then kept at these exact conditions until sufficient breakdown of solutes is achieved The used solvent is then let out of the cell, and an extraction solvent is forced through the system for a predetermined time known as dynamic extraction time. The resulting sample is then rapidly cooled in ice water using glass flasks to prevent degradation of the extract. Resulting End Product Trichomes are what is removed. This closed loop system will produce a thick goopy substance ranging from yellow to brown. Different temperatures and pressures will result with different end product consistencies. THC levels range from 70-90% Advantages of Water Based Extraction Elimination of additional sample clean up Reduction in organic solvent consumption High Selectivity Extraction efficiency Ease of automation Cheap solvent (water) Disadvantages of Water Based Extraction Relatively expensive start-up cost Long residence time of extracts has an increased risk of phytochemical degradation. Link to Lecture Slides: https://drive.google.com/file/d/1Fap_ONzmq3XMAcmj1CREfHh5LTZalt_5/view?usp=sharing *Due to the description character limit the full work cited for "Water Based Extraction of Cannabis" can be viewed at... https://drive.google.com/file/d/15ptqu6EHkZUXt3PhMB9y_jPqqH172VYN/view?usp=sharingSerena Leafz Cbd Gummies Canada Reviews Truth Revealed 2023 Serena Leafz Cbd Gummies CanadaIn this conversation, Dr. Riley Kirk and Dr. Josh Kaplan delve into the complexities of cannabis research, particularly focusing on CBD and its therapeutic potential for conditions like epilepsy. 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The conversation also delves into ongoing clinical trials, particularly within the NFL, and the challenges faced in cannabis research, including dosing and the variability of individual responses to cannabinoids. Kaplan highlights the importance of understanding the entourage effect and the need for more personalized approaches in cannabis treatment. More about Dr. Kaplan: Dr. Kaplan is an Associate Professor in the Behavioral Neuroscience Program. His expertise is in neurophysiology, neuropharmacology, and animal behavior techniques, which his lab uses to study the therapeutic benefits and developmental consequences of cannabis in pre-clinical rodent models. His research seeks to optimize cannabinoid and terpene compositions to maximize benefit and minimize adverse consequences. Dr. Kaplan has a strong passion for teaching and communicating science. His scientific writing specializes in the science of cannabis and its medicinal utility. He was included in High Times' 100 Most Influential People in Cannabis (2018) and Cannabis Newsletter's Top 100 (2021). Follow Dr.Kaplan’s research: https://wp.wwu.edu/kaplanlab/ Preorder my book Reefer Wellness! https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156 Seed Giveaway Thank you to Royal Queen Seeds and Last Green Valley Seeds for donating to this week's giveaway! To enter, fill out the form below, winners will be selected at random. https://forms.gle/1vWtsBMGaux9x5Mf6 ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! 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Whether you’re at work, traveling, or in public, hemp gummies offer a convenient way to incorporate CBD into your daily routine without drawing attention to yourself. They are easy to carry around and can be taken without the need for water, making them a convenient choice for busy individuals. Choosing the Right Hemp Gummies When it comes to selecting hemp gummies, it’s essential to choose a reputable brand that uses high-quality ingredients and transparent manufacturing processes. Look for hemp gummies that are made from organically grown hemp, free from pesticides and harmful chemicals. Additionally, opt for products that have been tested by a third-party laboratory to ensure potency and purity. hemp gummies cbd stimuli rx hemp gummies for ed cbd gummies pure organic hemp extract 300mg gummies marijuana enjoy hemp delta 8 gummies Another factor to consider when choosing hemp gummies is the CBD concentration per serving. 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TIME magazine reports that the United Kingdom’s Medicines and Healthcare Products Regulatory Agency (MHRA,similar to the United States FDA) says “We have come to the opinion that products containing cannabidiol are a medicine” citing numerous medical benefits as well as showing “restoring, correcting or modifying effects on physiological functions.” https://www.youtube.com/watch?v=zsRPC4wqbvM PAIN Cannabinoids show very promising results in dealing with pain, in both chronic pain and pain traditionally difficult to treat by conventional means. The analgesic effects cannabinoids produce often provide relief to patients that don’t respond well to other more common methods. “Patients most often ascertain an individual stable dosage within 7–10 days that provides therapeutic relief without unwanted psychotropic effects,” meaning that it’s easy to find your personal “right” dose safely. 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If you enjoyed this video please Like and Subscribe and don't forget to hit the bell 🛎 so you will be notified when I release a video or go live. Also please leave a comment and please share. (Warning) These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure, or prevent any disease. Information is not intended to be a substitute for medical advice, diagnosis, or treatment. Please consult your doctor or healthcare professional about potential interactions or other possible complications before using any product(s). If you have a product that you would like to have reviewed, You May contact me at: [email protected] Want to see more of my Content? 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