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Sleep disruptions are challenging for both patients and caregivers. During this session, we will review the current understanding of sleep/wake disruptions in PSP, CBD and MSA; we will hear about an on-going clinical sleep trial which grew from our observational studies; and we will briefly touch base on sleep hygiene factors. Dr. Christine M. Walsh, is an Assistant Professor at the University of California, San Francisco. She received her BA degree in physiology from Trinity College Dublin, University of Dublin in Ireland; and received her PhD from the department of Neuroscience at the University of Michigan. In 2011 Dr. Walsh joined the UCSF Memory and Aging Center where she has been studying sleep and rest-activity rhythms in both healthy older adults and in individuals with neurodegenerative diseases, particularly 4R tauopathies. For more information and resources, please visit: curepsp.org #CurePSP #BecauseHopeMatters #Nonprofit #PSP #CBD #MSA #Neurodegeneration #Support

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As athletes push their bodies to the limit, injuries are an unfortunate reality. But what if there was a natural way to aid in recovery and reduce pain? CBD has been gaining popularity among athletes for its potential benefits in reducing inflammation, promoting joint health, and providing natural pain relief. In this video, we'll explore the science behind CBD and its potential to help with sports injuries. From reducing muscle soreness to supporting athletic performance, we'll dive into the benefits of CBD for athletes and how it can be incorporated into a recovery routine. Whether you're a professional athlete or a weekend warrior, this video will provide you with valuable insights into the world of CBD and sports recovery. So, can CBD really help with sports injuries? Let's find out.

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CBD is one of a class of compounds known as cannabinoids, which are found in the cannabis plant. Unlike THC (the main psychoactive component of cannabis), CBD is not thought to have intoxicating effects. It is, however, believed to interact with the nervous system. In this video, I discuss what we know about CBD’s mechanism of action and its potential in treating various conditions like epilepsy and anxiety. TRANSCRIPT: CBD is one of a class of compounds known as cannabinoids, which are found in the cannabis plant. Unlike THC (the main psychoactive component of cannabis) CBD is not thought to have intoxicating effects. It is, however, believed to interact with the nervous system, which may enable it to modulate the effects of thc as well as have actions of its own. CBD is chemically similar to THC, but it does not have the same mechanism of action, and some evidence suggests it may even interfere with some of the actions of THC. One way it may do this is by binding to receptors that THC binds to known as CB1 receptors, but instead of activating them, causing a change in the receptor that reduces THC’s ability to interact with it. This type of effect is known as negative allosteric modulation, and it may enable CBD to mitigate some of the adverse effects of THC, like anxiety. Other research, however, suggests CBD can enhance certain effects of THC, and CBD is also thought to act at a number of other targets besides the CB1 receptor. For example, CBD is believed to activate serotonin receptors and may increase levels of a natural cannabinoid called anandamide by blocking anandamide reuptake and inhibiting the enzymatic breakdown of anandamide. Overall, although a number of targets for CBD have been identified, its mechanism of action is still poorly understood. CBD is generally well-tolerated, but some have raised concerns about the need for more research before we can be confident about its safety in all populations. CBD, however, is not thought to have potential for abuse, and some believe it does have potential for treating a number of conditions, like anxiety, insomnia, and pain. But most of these claims don’t yet have strong evidence to support them, and more research is needed, although CBD has been found to be a viable treatment for at least some types of epilepsy. REFERENCES: Laprairie RB, Bagher AM, Kelly ME, Denovan-Wright EM. Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor. Br J Pharmacol. 2015;172(20):4790-4805. doi:10.1111/bph.13250 McPartland JM, Duncan M, Di Marzo V, Pertwee RG. Are cannabidiol and Δ(9) -tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review. Br J Pharmacol. 2015;172(3):737-753. doi:10.1111/bph.12944 Pisanti S, Malfitano AM, Ciaglia E, et al. Cannabidiol: State of the art and new challenges for therapeutic applications. Pharmacol Ther. 2017;175:133-150. doi:10.1016/j.pharmthera.2017.02.041 World Health Organization (WHO). Cannabidiol (CBD): Pre-Review Report. November 2017. Accessed June 28, 2020. https://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf Special thanks to Srikar Gade for help with fact-checking this video.

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in this video I talk about why hhc has become my favorite cannabinoid. I am reviewing the new HHC flower strain called "Taz’s Love". This strain comes from a company called JK DISTRO. I do not sell these products I only review them. If you are under 18 please leave my child. All hemp products are 100% legal thanks for the farm bill. if you would like for me to review your products you can reach me at [email protected] #hhc #vs #love

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If you are interested, please contact us at [email protected] or WhatsApp +86-13819752271 Solvent extraction usually takes ethanol and butane as solvents and is extracted from cannabis plant excipients. The combination of the two is good, simple and easy to operate, and can be operated at home.Under the condition of guaranteeing extraction rate and purity, solvent is used in the whole process of extraction, which avoids the use and residue of toxic organic solvents such as petroleum ether and ensures safety of product .

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ARE CBD & THC THE SAME? CBD (cannabidiol) and THC (tetrahydrocannabinol) often get lumped together because they both are derived from hemp and are used therapeutically. But are they the same? Thomas DeLauer discusses what makes CBD and THC different. CBD and THC do different things in your body. They both ultimately act upon what are called CB1 and CB2 receptors in the body, but what's interesting is that CBD doesn't even directly affect those receptors. I'll make some sense of all this in just a second, but first off, let me just quickly explain what CBD is. CBD is usually an oil that's derived from maybe hemp or some other cannabis compound. What the whole purpose of CBD is, is to give you the non-psychoactive components of cannabis but with all the positive effects, but what we have to look at is that it really acts in a whole different system in the body. We have something in our bodies known as endocannabinoids. Endocannabinoids are our body's own natural way of stimulating the CB1 and CB2 receptors, basically to modulate inflammation or to modulate our nervous system or to really have different effects in the body. The CB1 receptors directly affect our brain and directly affect our nervous system, whereas the CB2 receptors directly affect our immune system. But the interesting thing is, is that CBD oil doesn't actually affect these at all. What it does is it stimulates the production of our body's natural endocannabinoids, and it slightly changes the structure of the CB1 and CB2 receptors. It allows your body to naturally create more of these endocannabinoids, whereas cannabis, you're directly putting a compound in your body that's going to directly affect these receptors. When you consume THC, or cannabis, that THC directly stimulates the CB1. It directly affects it. It binds with it perfectly, and it affects it, and it stimulates it, which is why you get the nervous system response and why you get the psychotropic response. There's very little stimulation or very little effect on the actual CB2 receptors. There is a little bit, so you do get some immune response, but most of it is psychological. Most of it is nervous system related. That's why you end up getting pain relief. That's why you end up getting the effects that are going to help you feel better, simply because you're stimulating that CB1 receptor. Then we look at CBD oil, which directly affects the CB1 receptor in an entirely different way. It changes the CB1's actual structure. It makes it more receptive to endocannabinoids. If you look at this one receptor that THC or cannabis usually stimulates, whenever you take CBD, it changes that structure. It makes it more enticing to your body's natural endocannabinoids. We're talking about anandamide, all these natural things that just help you feel good and feel relaxed and feel just a general sense of well-being. When you change that structure, you're making it more receptive to that, but what you're also doing is you're making it less receptive to THC. A lot of times, what people will do is they will actually combine CBD with THC because CBD blocks the ability for THC to really have that much of an effect. Basically, THC makes you high. CBD doesn't. In fact, CBD stops you from getting high. When you actually look at the difference between CBD and THC, people will always say that they're so similar and, "Oh, it's like a legal form of THC, or a legal form of cannabis." It's actually the anti-cannabis in a way. It's like the anti-THC. It's the other side of the equation that stimulates your body's natural production of these endocannabinoids and allows your body to use them naturally. What is CBD and CBD Oil? https://youtu.be/CwN-LByRLcw Does CBD Help Anxiety and Depression? https://youtu.be/Hvx3qbwao_4 Does CBD Stop Pain? https://youtu.be/PbnrRoceybk Is CBD Effective? https://youtu.be/DclklTCuCAg Does CBD Help You Sleep Better? https://youtu.be/0GAscp_akTY

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#cannabis #delta8 #cannabiseducation Join our co-founder Heather as she discusses Delta 8 THC! Learn what it is, how it differs from Delta 9 THC and how it will make you feel when using it! Will Delta 8 cause me to fail a drug test? When you’re being tested for cannabis use, you are typically being tested for THC consumption. While the test itself doesn’t test for Delta 9 THC, it DOES test for the metabolites that come from the THC. Metabolites are the smaller molecules that are left over once your body processes the compound. Delta 8 THC and Delta 9 THC have some of the same metabolites. This is important to note as regularly using either of these products CAN result in a failed drug test even if they are in smaller doses like a Full Spectrum or Delta 8 only product. Is Delta 8 legal in my state? Alabama: Delta 8 is legal in Alabama Alaska: Delta 8 is illegal in Alaska Arizona: Delta 8 is illegal in Arizona Arkansas: Delta 8 is illegal in Arkansas California: Delta 8 is legal in California Colorado: Delta 8 is illegal in Colorado Connecticut: Delta 8 is legal in Connecticut Delaware: Delta 8 is illegal in Delaware Florida: Delta 8 is legal in Florida Georgia: Delta 8 is legal in Georgia Hawaii: Delta 8 is legal in Hawaii Idaho: Delta 8 is illegal in Idaho Illinois: Delta 8 is legal in Illinois Indiana: Delta 8 is legal in Indiana Iowa: Delta 8 is illegal in Iowa Kansas: Delta 8 is legal in Kansas Kentucky: Delta 8 is legal in Kentucky Louisiana: Delta 8 is legal in Louisiana Maine: Delta 8 is legal in Maine Maryland: Delta 8 is legal in Maryland Massachusetts: Delta 8 is legal in Massachusetts Michigan: Delta 8 is legal in Michigan Minnesota: Delta 8 is legal in Minnesota Mississippi: Delta 8 is illegal in Mississippi Missouri: Delta 8 is legal in Missouri Montana: Delta 8 is illegal in Montana Nebraska: Delta 8 is legal in Nebraska Nevada: Delta 8 is legal in Nevada New Hampshire: Delta 8 is legal in New Hampshire New Jersey: Delta 8 is legal in New Jersey New Mexico: Delta 8 is legal in New Mexico New York: Delta 8 is legal in New York North Carolina: Delta 8 is legal in North Carolina North Dakota: Delta 8 is legal in North Dakota Ohio: Delta 8 is legal in Ohio Oklahoma: Delta 8 is legal in Oklahoma Oregon: Delta 8 is legal in Oregon Pennsylvania: Delta 8 is legal in Pennsylvania Rhode Island: Delta 8 is illegal in Rhode Island South Carolina: Delta 8 is legal in South Carolina South Dakota: Delta 8 is legal in South Dakota Tennessee: Delta 8 is legal in Tennessee Texas: Delta 8 is legal in Texas Utah: Delta 8 is illegal in Utah Vermont: Delta 8 is legal in Vermont Virginia: Delta 8 is legal in Virginia Washington: Delta 8 is legal in Washington West Virginia: Delta 8 is legal in West Virginia Wisconsin: Delta 8 is legal in Wisconsin Wyoming: Delta 8 is legal in Wyoming Want to learn more? Visit our blog at kchempco.com

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🌿 Young and Beautiful: Oral Capsule Creation Strain Inspiration: Young and Beautiful Musical Muse: One Nite Alone album by Prince Cannabinoid Profile: Balanced 1:1 CBD:THC ratio Format: Oral Capsules Purpose: Pain relief, relaxation, anxiety reduction, daily wellness 🧪 Step-by-Step: Making Oral Cannabis Capsules 1. Choose the Strain(s) Select CBD-dominant and THC-dominant strains that complement each other. For “Young and Beautiful,” we suggest a Prince-worthy pairing: CBD strain: Something soothing and floral THC strain: Something euphoric but clear-headed 2. Decarboxylation This activates the cannabinoids so they’re bioavailable when taken orally. Grind your cannabis flower finely. Oven Bake at 240°F (115°C) for: 30–40 minutes (THC) Let it cool completely. 3. Infuse the Oil Use MCT oil, olive oil, or grapeseed oil. MCT is preferred for easy digestion and absorption. Combine equal weights of decarbed CBD and THC flower with oil. Use a MagicalButter Machine, Nova FX, or slow cooker: Temperature: 160°F–180°F Time: 2–4 hours (stir occasionally if doing manually) 4. Strain and Cool Use cheesecloth or a fine metal strainer to remove plant material. Let oil cool to room temp. 5. Fill the Capsules Use size 0 or 00 gelatin or vegan capsules. Fill each capsule with 0.5 ml – 1 ml of infused oil using a dropper or capsule-filler tray. Store in a cool, dark place or refrigerator. 🔮 Dosage Guidance Start Low: 3.5 mg total cannabinoids per capsule. 1 “Young and Beautiful” aims for balance, calm, and clarity—not sedation. 🧘🏾‍♂️ The Prince Touch Each capsule is a royal tribute: Named after the sensual, spiritual energy of One Nite Alone Crafted to honor Prince’s creative duality—masculine/feminine, calm/passion, light/shadow Designed to “Elevate the Everyday”—whether it’s pain relief or soulful meditation CannaChefMD – Cooking up vibes, flavor, and funky edible Creations Subscribe for more!

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You probably don't have a problem playing video games or browsing social media on your phone. In fact I have no doubt you could sit in front of a screen and do both of those activities for 2 hours, or even longer without breaking your concentration. But what about half an hour of studying? That might be too hard. How about working on your side business for another hour? Doesn't sound too appealing. Even though you logically know that studying, exercising, building a business or something equally productive, will bring you more benefits in the long run, you still prefer watching TV, playing video games and scrolling through social media. One might argue that it's obvious why. One activity is easy and doesn't require much effort, while the other activity is difficult and it requires you to apply yourself. But some people seem to have no problem studying, exercising, or working on their side projects, regularly. Which begs the question: Why are some people more motivated to tackle difficult things? And is there a way to make doing difficult things, easy? References: https://www.psychologytoday.com/intl/blog/the-athletes-way/201405/the-neuroscience-pleasure-and-addiction https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791340/ https://www.cell.com/cell/fulltext/0092-8674(95)90145-0 https://www.centersite.net/poc/view_doc.php?type=doc&id=48370&cn=1408 Images © Piers Baker www.svgdoodlewhiteboard.com

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POT TV - Marijuana Man is back at the Seed Desk and broadcasting LIVE every Wednesday at 4PM Pacific on From Under the Seed Desk. On today's show: To CBD or Not to CBD, that is the question. Grab a joint and join the chat. In his weekly show From Under the Seed Desk, Greg Williams (also known as Marijuana Man), manager of the Pot TV Network and one of Prince of Pot Marc Emery's co-accused in his international seed-selling case, talks directly with viewers about marijuana, hemp, the drug war, pot politics and anything else he wants to discuss. Marijuana Man is joined by Mz Kush Queen and growing expert Al the Alchemist for the broadcast LIVE every Wednesday from the new location of The Vancouver Seed Bank at CCHQ. Cannabis Culture editor Jeremiah Vandermeer takes your questions in the Livestream chatroom. Originally broadcast on May 13, 2015

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Come play in the sand with us as we are finally in Galveston! We decided to review some Smokiez gummies in hopes it would give us the energy to get through a rainy day. As always we hope you guys have a great day/night and remember to spread the peace! Past edibles reviews- Squib Gummies: https://www.youtube.com/watch?v=8G0uy08bGNo&t=8s CBD Mints: https://www.youtube.com/watch?v=tKlp152QsFs&t=55s CBD Chocolates: https://www.youtube.com/watch?v=-qou5F_AB6s&t=174s CBD in video- Smokiez Jamberry CBD gummies: https://www.shopcbdnow.com/product/smokiez-edibles-cbd-gummiez-jamberry-250mg/ Ladies of Paradise Lady Jays: https://shopladyjays.com/lady-jays-cbg-10-5g-pack-ladies-orange-peel/ Our Socials- Instagram: https://www.instagram.com/weedabest_cbd/ Facebook: https://m.facebook.com/weedabesthereis/ Twitter: https://mobile.twitter.com/weedabesthereis TheWeedTube: https://www.theweedtube.com/user/Weedabest *We don't sell any of these products we only review them! Only watch if you're 18+ please!* #smokiez #edibles #CBDedibles

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Hi guys, The hemp hand protector is £5 for 30ml at The Body Shop, they have a whole line for dry skin. Hope you have a lovely day Ellie