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Zamir Punja, PhD is a Professor of Plant Biotechnology at Simon Fraser University in Canada. His research interests include the etiology and management of plant diseases on vegetable and horticultural crops, and the applications of plant biotechnology for disease management. Since 2018, his work has shifted to researching cannabis, where his group has described a range of previously unreported pathogens affecting the crop and has evaluated various methods for disease management. At CannMed 25, Zamir will present his team’s latest work investigating the microbiome of cannabis and hemp plants. Using Next-Generation Sequencing and microscopy, his team identified diverse fungi, yeasts, and bacteria across plant tissues. Their study reveals that cannabis plants host abundant microbial endophytes, which can impact plant health and product quality. Findings also highlight the influence of growing substrates and biocontrol agents on the cannabis microbiome. During our conversation, we discuss: * What is the microbiome and how do microbial endophytes affect plant health * Identification of common microbes found in cannabis samples, including Penicillium and Fusarium. * Whether meristem tissue culture is a viable microbial sterilization method. * The influence of sterilized vs. non-sterilized growing media. * How growers can use microbiome analysis for early interventions. * Insights into beneficial fungi like Trichoderma and Mycorrhizae. * Future research questions on microbial balance and seed microbiome engineering. * And More Thanks to This Episode’s Sponsor: GrowDefender GrowDefender provides long-lasting antimicrobial protection for indoor cultivation and processing spaces. Using patented Goldshield® technology, their EPA-registered, water-based products protect surfaces from mold, mildew, bacteria, and fungi for up to 90 days. Safe, non-toxic, and easy to apply, GrowDefender helps growers reduce contamination, protect crops, and maintain cleaner, healthier environments. Learn more at growdefender.com Additional Resources - Endophytes in Cannabis sativa: Identifying and Characterizing Microbes with Beneficial and Detrimental Effects on Plant Health - https://pmc.ncbi.nlm.nih.gov/articles/PMC12030312/ - Exploring the fascinating development of cannabinoid-producing trichomes - https://youtu.be/Avhr8XjsBTU?si=nbYpjuoMMnKVqF6X - Register for CannMed 25 - https://cvent.me/emBPno - Meet the CannMed 25 Speakers and Poster Presenters - https://cannmedevents.com/speakers/ - Review the Podcast - https://podcasts.apple.com/us/podcast/cannmed- - CannMed Archive - coffee-talk/id1504218804 - https://cannmedevents.com/cannmed-video-archives/

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When it comes to enjoying cannabis-infused edibles like gummies, one of the common concerns that many users have is whether these treats have a shelf life. While traditional gummies may eventually go bad due to the ingredients they contain, marijuana gummies are a bit different. The addition of THC or CBD can affect the overall stability and longevity of the product. So, do marijuana gummies go bad? Let’s delve into the shelf life secrets of these popular edibles.

Factors Affecting Shelf Life

Several factors can influence the shelf life of marijuana gummies. The primary one is the way they are stored. Just like any other food product, exposure to heat, light, and air can cause the gummies to degrade faster. Storing them in a cool, dark place can help extend their shelf life. Additionally, the ingredients used in the gummies, such as preservatives and stabilizers, can impact how long they remain fresh.

Another crucial factor to consider is the type of packaging used for the gummies. Properly sealed packaging can help protect the product from external elements that could lead to spoilage. If the packaging is inadequate or damaged, the gummies may not last as long as they should. It’s essential to check the packaging for any signs of tampering or deterioration before consuming the gummies.

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The potency of the cannabinoids in the gummies can also affect their shelf life. Over time, THC and CBD can degrade and lose their effectiveness, which can impact the overall quality of the product. Properly storing the gummies in airtight containers and consuming them within a reasonable timeframe can help preserve the potency of the cannabinoids.

Signs of Spoilage

Like any other perishable item, marijuana gummies can go bad if not stored correctly or consumed within a reasonable timeframe. There are several signs to look out for that indicate the gummies may have spoiled. One of the most obvious indicators is a change in color or texture. If the gummies appear discolored, moldy, or unusually hard or soft, it’s best to discard them.

Another telltale sign of spoilage is a strange or off-putting odor coming from the gummies. If the gummies smell unusual or unpleasant, it’s a clear sign that they are no longer safe to consume. In some cases, you may also notice a change in taste when consuming the gummies. If they taste different from what you’re used to, it’s best to err on the side of caution and avoid consuming them.

If you experience any adverse effects after consuming marijuana gummies, such as nausea, vomiting, or stomach pain, it’s essential to stop consumption immediately and seek medical attention. These symptoms could indicate that the gummies have gone bad or that you may have consumed too much THC or CBD.

Proper Storage Tips

To maximize the shelf life of your marijuana gummies, it’s crucial to store them properly. Ideally, you should keep them in a cool, dark place away from heat sources and direct sunlight. High temperatures can cause the gummies to melt or degrade faster, while exposure to light can impact the potency of the cannabinoids.

It’s also essential to store the gummies in airtight containers to prevent air and moisture from affecting their quality. This will help preserve the freshness and potency of the product for a more extended period. If the gummies come in resealable packaging, make sure to seal it tightly after each use to maintain their freshness.

If you live in a particularly humid or hot climate, consider storing the gummies in the refrigerator or freezer. Just be sure to thaw them at room temperature before consuming to avoid any changes in texture. With the right storage conditions, you can enjoy your marijuana gummies for an extended period without worrying about spoilage.

Conclusion

Overall, marijuana gummies can go bad if not stored correctly or consumed within a reasonable timeframe. By considering factors such as storage conditions, packaging, and cannabinoid potency, you can prolong the shelf life of these popular edibles. Keep an eye out for any signs of spoilage, such as changes in color, texture, odor, or taste, and discard any gummies that show these characteristics. With proper storage and attentive consumption, you can enjoy your marijuana gummies safely and deliciously.

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A new disease called "cannabis hyperemesis syndrome" is on the rise due to increased marijuana use. In this video we explain the science behind what is going on. Some scientists think that the legalization of marijuana may be under threat, other think awareness is all the matters - let's see how it all plays out. Written by: Gregory Brown Edited by: Luka Šarlija Drawings by: Max Simmons Thank you to Marieka DeVuono, PhD for your help on this video. References: https://pubmed.ncbi.nlm.nih.gov/32656345/ https://www.newscientist.com/article/2398836-mysterious-cannabis-induced-vomiting-syndrome-is-on-the-rise/ https://www.sciencedirect.com/science/article/abs/pii/S0262407923020857 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2812392?resultClick=3 https://med.stanford.edu/news/all-news/2023/11/twin-diet-vegan-cardiovascular.html https://www.cnn.com/2021/09/17/health/marijuana-vomiting-wellness/index.html

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Anxiety is a common mental health issue that affects millions of people worldwide. It can manifest in many different ways, including feelings of worry, fear, and unease. While some people may experience mild anxiety that is manageable, others may struggle with severe anxiety that significantly impacts their daily life. Fortunately, there are various treatment options available to help manage anxiety, including therapy, medication, and lifestyle changes. One alternative treatment that has gained popularity in recent years is the use of CBD oil.

What is CBD oil?

CBD, or cannabidiol, is a compound derived from the cannabis plant. Unlike THC, another compound found in cannabis, CBD is non-psychoactive, meaning it does not produce a “high.” CBD oil is made by extracting CBD from the cannabis plant and diluting it with a carrier oil, such as coconut or hemp seed oil. It is available in various forms, including tinctures, capsules, and topicals.

Research has shown that CBD may have potential therapeutic benefits for a range of conditions, including anxiety, pain, insomnia, and epilepsy. While more research is needed to fully understand how CBD works and its effects on the body, many people have reported positive experiences with using CBD oil to manage their anxiety.

When it comes to anxiety, CBD is thought to interact with the body’s endocannabinoid system, which plays a role in regulating stress and anxiety. By interacting with receptors in the brain and immune system, CBD may help reduce feelings of anxiety and promote a sense of calm. Additionally, CBD has been shown to have anti-inflammatory and neuroprotective properties, which may also contribute to its anxiety-relieving effects.

How can CBD oil help with anxiety?

One of the primary ways that CBD oil may help with anxiety is by reducing the activity of the amygdala, a part of the brain that is involved in the processing of emotions such as fear and stress. Studies have shown that CBD can help dampen the response of the amygdala to stressful stimuli, leading to a reduction in anxiety levels.

In addition to its effects on the amygdala, CBD has also been found to increase levels of serotonin, a neurotransmitter that plays a key role in regulating mood. Low levels of serotonin have been linked to anxiety and depression, so increasing serotonin levels with CBD could help alleviate symptoms of anxiety.

Furthermore, CBD has been shown to promote neurogenesis, the growth and development of new neurons in the brain. This process is important for maintaining healthy brain function and has been implicated in the treatment of anxiety disorders. By promoting neurogenesis, CBD may help improve brain plasticity and resilience to stress, leading to a reduction in anxiety symptoms.

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When used correctly and in moderation, CBD oil is generally considered safe for anxiety. However, it is important to note that CBD can interact with certain medications, so it is essential to consult with a healthcare provider before starting a CBD regimen, especially if you are taking other medications.

Some people may experience side effects when using CBD oil, such as dry mouth, dizziness, changes in appetite, and diarrhea. These side effects are typically mild and temporary, but if you experience any severe or persistent side effects, you should discontinue use and consult with a healthcare provider.

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Conclusion

In conclusion, CBD oil shows promise as a natural remedy for anxiety due to its interactions with the endocannabinoid system, serotonin levels, and neurogenesis. While more research is needed to fully understand the mechanisms behind CBD’s anxiety-relieving effects, many people have found relief from their symptoms by using CBD oil. If you are considering trying CBD oil for anxiety, be sure to consult with a healthcare provider to determine the best approach for your individual needs.

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CBD oil with THC has become increasingly popular in recent years for its potential health benefits. As the legalization of cannabis spreads, more and more people are turning to this powerful combination of cannabinoids for relief from a variety of ailments. In this article, we will explore the benefits, dosage recommendations, and legal status of CBD oil with THC.

Benefits of CBD Oil with THC

CBD oil with THC offers a wide range of potential health benefits, thanks to the combined effects of these two cannabinoids. THC is well known for its psychoactive properties, but it also has anti-inflammatory, analgesic, and neuroprotective properties. When combined with CBD, which is non-psychoactive and has its own set of therapeutic effects, the two cannabinoids work synergistically to provide relief from pain, anxiety, inflammation, and more.

One of the primary benefits of CBD oil with THC is its ability to provide relief from chronic pain. Studies have shown that the combination of these two cannabinoids can be more effective in reducing pain than either one alone. This makes CBD oil with THC a popular choice for those suffering from conditions such as arthritis, fibromyalgia, and multiple sclerosis.

In addition to pain relief, CBD oil with THC has been shown to have powerful anti-anxiety properties. Both cannabinoids have anxiolytic effects, meaning they can help reduce feelings of anxiety and stress. This can be particularly beneficial for those with generalized anxiety disorder, social anxiety, or PTSD.

Recommended Dosage of CBD Oil with THC

When it comes to dosing CBD oil with THC, it’s important to start low and go slow. The optimal dosage will vary depending on factors such as the individual’s weight, metabolism, and the severity of their symptoms. It’s recommended to begin with a low dose of CBD oil with a higher ratio of CBD to THC, gradually increasing the dose until the desired effects are achieved.

A common starting dose is 5-10 mg of CBD with a small amount of THC, taken once or twice daily. For those with more severe symptoms, higher doses may be necessary. It’s best to consult with a healthcare provider experienced in cannabis medicine to determine the most appropriate dose for your specific needs.

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It’s also important to consider the method of administration when determining the dosage of CBD oil with THC. Sublingual tinctures, capsules, and edibles all have different absorption rates and bioavailability, which can affect the amount of cannabinoids that reach the bloodstream. Experimenting with different methods may help you find the most effective dose for your condition.

Legality of CBD Oil with THC

The legality of CBD oil with THC varies depending on where you live. In the United States, CBD derived from hemp with less than 0.3% THC is legal at the federal level. However, CBD derived from marijuana with higher levels of THC is still considered a Schedule I controlled substance under federal law.

Individual states have their own laws regarding the use of CBD oil with THC, so it’s important to research the regulations in your area. Some states have legalized both medical and recreational cannabis, allowing for the use of CBD oil with higher levels of THC. Others have strict regulations in place, only permitting the use of CBD with very low levels of THC.

It’s crucial to stay informed about the legal status of CBD oil with THC in your jurisdiction to avoid any potential legal issues. Additionally, purchasing CBD products from reputable sources that provide third-party lab testing can help ensure that you are getting a safe and legal product.

Overall, CBD oil with THC has the potential to offer significant health benefits for those suffering from a variety of conditions. By understanding the benefits, recommended dosage, and legal status of this powerful combination of cannabinoids, individuals can make informed decisions about incorporating it into their health and wellness routine.

Summary and FAQ

In conclusion, CBD oil with THC can provide relief from chronic pain, anxiety, inflammation, and more. Dosage recommendations vary depending on individual factors, and it’s important to start with a low dose and gradually increase until the desired effects are achieved. The legality of CBD oil with THC depends on where you live, so it’s essential to research the laws in your area to ensure compliance. By staying informed and working with a healthcare provider experienced in cannabis medicine, individuals can experience the potential benefits of CBD oil with THC safely and legally.

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