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Much of THC's ability to relieve pain is due to its interaction with CB1 receptors in the midbrain. Delta-8 THC Explained Delta-8-THC is an isomer of Delta-9 THC It only differs from delta-9-THC by the placement of one atomic double bond. Generally, this chemical is produced in a lab, not extracted directly from the plant. It is actually synthesized from CBD Isolate. This creates a legal loophole, because the product is being sold as “hemp derived” even though it is actually a chemically produced THC isomer. Extraction Difference Delta 9 THC is a major cannabinoid that can be found in abundance and is easily extracted from in cannabis. Extracting Delta 8 THC is more challenging because it is a minor cannabinoid Synthesizing Delta 8 from CBD Delta 8 can be synthesized entirely from CBD with the use of solvents. Deriving Delta 8 from hemp ensures the final product is under the 0.3% THC level to be federally legal. Steps to Synthesize D8 THC from CBD isolate Dissolve into non-polar solvent of choice. Common solvents include heptane. Add a Lewis acid, like alumina, p-toluenesulfonic, or hydrochloric. Maintain the mixture at a temperature of 100 degrees C while continually stirring for upwards of 18 hours. Once the chemical reaction is complete, and the upper phase is separated, wash and neutralize the solution with 5% NaHCO3 Test for purity and contaminants using HPLC, separate the converted mixture into its “many cannabinoid parts”. Conversion is never 100% Different Effects Delta 9 is considerably more potent effects than Delta 8. Ex. paranoid delusions, mental fog, impaired motor skills, and increased feelings of anxiety. Delta 8 is reported to provide a more muted experience with most users feel a great sense of calm and clarity. However, many have reported a definite “high” to the experience, but not enough to impair the ability to form coherent thoughts or focus on activities. Onset Time Difference Delta 9 has an onset that is more rapid and instantaneous Delta 8 works slowly and gradually as it eases users into a more mellow state Similar End Products Both can be smoked as a flower, inhaled through vaping, consumed in edible form also with a wide variety of topicals, capsules, tinctures, edibles and other products. Legality Delta 9 THC in any amount over 0.3% is not legal at a federal level. State level depends entirely on their local laws. Delta 8 is still technically legal on a federal level. That's because of the ambiguities of the 2018 Farm Bill, which legalized hemp production. There is nothing within the bill that prohibits deriving Delta 8 from hemp and creating products with the compound. Hazy Area The psychoactive nature of Delta 8 has prompted a fair number of bans at the state level, though. Currently there are 15 states that restrict the sale and use of Delta 8 products, with another 6 states where legal action is pending. So while Delta 8 is more widespread at the moment than Delta 9, how long that will last has yet to be determined. Availability Delta 8 since it is federally legal can be shipped across state lines, unlike Delta 9. There are a lot more online retailers for Delta 8 products as a result. Remember: Delta 8 products are not regulated by the FDA, so it is up to you to seek out lab results tested from a third party lab. Delta 9 vs Delta 8 Delta 9 might be considered the “classic” choice by some within the cannabis community, Delta 8 has been quickly gaining in popularity due to its milder effects and legal availability. Since this is an isomer of Delta 9 it is also likely to come under some form of regulation in the future even though that may not currently be the case. 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