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In this video, I'll explain marijuana metabolism. I'll show how our body processes and excretes marijuana and its metabolites. Possessing this knowledge is extremely important in your understanding of how to detox from marijuana. DELTA-9-THC or THC is the primary psychoactive ingredient of cannabis. When cannabis is smoked or vaporized, THC enters the bloodstream via absorption through the lungs. According to a research study, we inhale only about 50% of the THC from the joint. Approximately 30% of the THC is destroyed by heat. Other THC is lost through sidestream and incomplete absorption in the lungs. Therefore, only a part of inhaled THC reaches body circulation due to what is called the first-pass metabolism. Because of the first-pass metabolism only 25-30% of smoked THC is absorbed into the blood. Studies have shown that heavy users receive ~25% of the THC available for absorbtion while occasional users get ~12%, the reason being because heavy users smoke more efficiently. When ingested as edibles, THC enters the bloodstream through the walls of the stomach and intestines. Tests show that 90-95% of the THC then permeates the blood after ingestion. THC and some of its metabolites are fat-soluble. This means that they can dissolve in fats or oils. THC rapidly penetrates highly vascularized tissues such as the lungs, liver, heart, and body fat. About 70% of the THC is taken up by tissues, mostly by body fat. The THC is then slowly released back into the blood. Through this process, THC is continuously moving from the fat tissues into the blood and back again. Once in the blood, THC infiltrates the liver and undergoes 2 phases of metabolism. The CYP2C9 enzyme converts THC to 11-OH-THC in the first phase, after which CYP2C19 and CYP3A4 enzymes convert 11-OH-THC to 11-COOH-THC. THC metabolites are prepared for excretion in the second phase. UGT enzymes add a glucuronide molecule to metabolites through a process known as glucuronidation. 11-COOH-THC is metabolized mainly by the UGT1A3 enzyme and forms THC-COO-Gluc. 11-OH-THC is metabolized mainly by UGT1A9 and UGT1A10 enzymes and forms THC-O-Gluc. The resulting metabolites are soluble in water. Afterwards, they are dissolved in the bile and water and excreted with the urine and feces. In the intestines, bacterial enzymes 'remove' glucuronide from most of the THC metabolites. These metabolites are then reabsorbed back into the blood, where they can begin the entire cycle over again. This process is called enterohepatic circulation. One unfortunate aspect of this process is that only about 20% of THC metabolites are excreted with the urine, while 65% are excreted with the feces. Therefore, most of the THC metabolites will enter the enterohepatic recirculation and return into your blood. This is why detoxification from marijuana is such a lengthy process. Need to detox from weed? Here are the best THC(marijuana) Detox Kits to detox from weed and pass your drug test with flying colors. đŸ‘đŸ» Most effective THC detox kits for passing a drug test: đŸ‘đŸ»đŸ‘đŸ»đŸ‘đŸ» Fast Marijuana Detox Kit(extra strong): https://greenfleets.org/products/fast-thc-marijuana-detox-kit-extra-strong/?utm_source=youtube.com&utm_medium=referral&utm_campaign=weedmetabolism&utm_term=fastdetoxstrong đŸ‘đŸ»đŸ‘đŸ»đŸ‘đŸ» Green Fleets Premium 7-day THC Detox Kit: https://greenfleets.org/products/premium-detox-7-day-comprehensive-cleansing-program-p2706.html?utm_source=youtube.com&utm_medium=referral&utm_campaign=weedmetabolism&utm_term=gf7day đŸ‘©â€âš•ïž The ultimate guide to passing a urine drug test: https://greenfleets.org/pass-drug-test/?utm_source=youtube.com&utm_medium=referral&utm_campaign=weedmetabolism&utm_term=detoxkits 😍 Subscribe to our channel if you want more information about the ways to detox and pass a drug test: http://www.youtube.com.com/c/ThcdetoxUsofficial Green Fleets has helped to pass a drug test for more than 50000 marijuana users. And each year, we continue to help more people to find a solution to pass urine, hair, and saliva drug tests for marijuana. We know that passing a pre-employment drug test can be very important for you. And it’s hard to find a trusted source of information. We get it! This is the reason we created Green Fleets. 😎 Visit our website for more in-depth information about ways to pass a drug test: https://greenfleets.org/?utm_source=youtube.com&utm_medium=referral&utm_campaign=weedmetabolism&utm_term=mainpage 0:00 Why it's important to understand marijuana metabolism 0:21 How much THC gets into the blood after smoking 1:18 How much THC gets into the blood after ingestion 1:32 How THC is stored in the body 2:10 Phase 1 of marijuana metabolism 2:34 Phase 2 of marijuana metabolism 3:15 Excretion of THC 3:26 Enterohepatic circulation of THC metabolites 4:07 How to speed up THC detoxification

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CBD products have gained immense popularity in recent years due to their potential health benefits. One such product that has garnered a lot of attention is the 50 mg CBD gummy bears. These delicious treats not only offer a convenient way to consume CBD but also promise to deliver a potent dose of this beneficial compound. In this article, we will delve into the impact of 50 mg CBD gummy bears and explore their effects on the body and mind.

Understanding CBD Gummy Bears

Before we dive into the effects of 50 mg CBD gummy bears, let’s first understand what these products are. CBD gummy bears are tasty, chewy candies infused with cannabidiol (CBD) extracted from the hemp plant. Each gummy bear typically contains a specific dosage of CBD, with 50 mg being a moderate to high dose, depending on individual tolerance levels. These gummies offer a convenient and discreet way to incorporate CBD into your daily wellness routine.

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When consumed, CBD interacts with the body’s endocannabinoid system, a complex network of receptors that play a crucial role in regulating various physiological functions, such as mood, pain sensation, sleep, and appetite. By tapping into this system, CBD gummy bears may help promote a sense of balance and overall well-being.

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1. Pain Relief: Many people turn to CBD products, including gummy bears, to manage pain naturally. CBD has anti-inflammatory properties that may help reduce pain and discomfort. The 50 mg dosage in these gummies offers a higher concentration of CBD, making them particularly effective for individuals dealing with chronic pain conditions.

2. Anxiety and Stress Reduction: Another common reason for using CBD gummy bears is to alleviate feelings of anxiety and stress. CBD has been shown to have calming effects on the mind and body, potentially helping to reduce symptoms of anxiety and improve overall mood. The 50 mg dose may provide a more significant relief for those dealing with high levels of stress.

3. Improved Sleep Quality: CBD is also known for its potential to promote better sleep quality. By calming the mind and relaxing the body, CBD gummy bears may help individuals fall asleep faster and enjoy a more restful night’s sleep. The 50 mg dosage can offer a more pronounced sedative effect, making it ideal for those struggling with insomnia or sleep disturbances.

Considerations and Precautions

Before incorporating 50 mg CBD gummy bears into your wellness routine, it’s essential to consider a few factors. Firstly, it’s crucial to consult with a healthcare professional to determine the appropriate dosage for your individual needs and health condition. While CBD is generally well-tolerated, it may interact with certain medications, so it’s essential to ensure it’s safe for you to consume.

Additionally, it’s essential to choose high-quality CBD gummy bears from reputable brands to ensure their potency and purity. Reading product labels and third-party lab reports can help you verify the quality and safety of the gummies you’re considering. Start with a lower dosage and gradually increase it as needed to gauge your body’s response and tolerance to CBD.

Conclusion

Overall, 50 mg CBD gummy bears can offer a potent dose of CBD with potential benefits for pain relief, anxiety reduction, and sleep improvement. These delicious treats provide a convenient and enjoyable way to incorporate CBD into your daily wellness routine. However, it’s crucial to approach CBD consumption mindfully, consider individual factors, and seek guidance from healthcare professionals to ensure a safe and effective experience.

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