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Delta-8 THC has become a popular alternative to Delta-9 THC in markets where legal cannabis isn't available. Sold widely in a variety of channels -- Hemp Boutiques, Head Shops, gas stations and online shopping destinations -- and marketed as safe and legal, the quality and potency of the commercially available Delta-8 THC products are inconsistent, unreliable and potentially dangerous, due to a lack of industry standards or government regulation. According to a recent study conducted by Leafreport, 63% of the 38 products that they purchased tested contained the wrong amount of Delta-8 -- more than 50% also had illegal (over 0.3%) levels of Delta-9 THC. The study's authors -- Nurse Practitioner Elosie Theisen and CBD Journalist Gleb Oleinik -- are featured guests this week on Curt's Cannabis Corner, joining host Curt Robbins and co-host David Rheins for a in-depth discussion about the science and business of Delta-8 THC, the results of the Leafwire Delta-8 THC Product Market Report, and how state's are regulating the phytomolecule (11 states have passed laws making the sale of Delta-8 THC illegal). Curt's Cannabis Corner is a series of articles and podcasts produced by Higher Learning LV and MJNews Network specifically for cannabis industry professionals. We hope that you dig the video. If you did, please Like, Share and Subscribe. Turn On. Tune In. Catch the Buzz. Marijuana Channel One is a creation of MJBA Publishing LLC. @2021 All rights are reserved. For more information, contact us at: [email protected] #mjnews #MJChannelOne BE HERE NOW #CannafestDestiny

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Cannabidiol, also known as CBD, has gained popularity in recent years for its potential health benefits. As more people turn to CBD for relief from various conditions, it’s important to understand how this compound works in the body. One crucial aspect of CBD’s effectiveness is its half-life, which refers to the time it takes for half of the substance to be eliminated from the body. In this article, we will delve into the concept of the half-life of cannabidiol and what you need to know about it.

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Before we explore the half-life of cannabidiol, let’s first understand what half-life means in general. Half-life is a pharmacokinetic measurement that indicates how long a substance remains in the body before it is metabolized and excreted. This concept is crucial for determining the dosing frequency of medications and assessing their effectiveness over time. In simple terms, the half-life of a substance determines how long it stays active in the body.

When it comes to CBD, the half-life can vary depending on various factors such as the method of administration, dosage, and individual differences in metabolism. Understanding the half-life of cannabidiol is essential for optimizing the therapeutic effects of CBD and avoiding potential side effects due to accumulation in the body.

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The half-life of cannabidiol can be influenced by several factors, including the method of administration. When CBD is ingested orally, such as through capsules or edibles, it has to pass through the digestive system before entering the bloodstream. This process can delay the onset of effects but prolong the duration of action as the CBD is gradually released into the bloodstream over time.

Metabolism of CBD

CBD is metabolized in the liver by enzymes such as cytochrome P450 (CYP450), which play a crucial role in breaking down various substances in the body. The metabolism of CBD can affect its half-life and overall bioavailability. Studies have shown that genetic variations in CYP450 enzymes can impact how individuals metabolize CBD, leading to differences in its effects and duration of action.

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Additionally, the dosage of CBD can also influence its half-life and effectiveness. Higher doses of CBD may take longer to be metabolized and eliminated from the body, resulting in a longer half-life. It’s important to find the right dose of CBD that provides the desired therapeutic effects without causing adverse reactions or accumulation over time.

Conclusion

In conclusion, understanding the half-life of cannabidiol is crucial for maximizing its therapeutic effects and ensuring safe and effective use. By considering factors such as the method of administration, metabolism, and dosage, individuals can tailor their CBD regimen to suit their specific needs and preferences. As more research is conducted on CBD and its pharmacokinetics, we can gain a better understanding of how this compound interacts with the body and how to optimize its benefits for overall health and well-being.

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Today I'm talking about CBD oil and insomnia. Personally, I've had trouble sleeping for several years, since I became an attending and started working more hours. Surprisingly to me, my attending hours and call turned out to be more than my hours and call in training, leading to trouble sleeping. So I'm always interested in hearing what other people's sleep solutions are. In the last year or so I've heard a lot of bloggers talk about CBD oil for insomnia, so I wanted to know what medical studies there were to support this. CBD oil that comes from hemp is meant to have little to no THC, less than 0.3-0.5% depending on your state's regulations. CBD oil can also come from marijuana, that has more THC in it. THC is the part that gives people the feeling of being high. So you're not supposed to get the high effects you’d get from marijuana, but you're still supposed to get the calming effects. CBD oil made from hemp is legal in all 50 states. Looking at the research, there's not a lot of research on CBD oil yet. Some of the research shows it can actually make you more alert. Some research shows it could help you sleep, so it's mixed data on whether or not it could help you sleep. Although people do say that it helps them sleep. Potentially the difference is because of dosing, at higher doses it could be more likely to help you sleep. Some studies theorize potentially it helps with anxiety, so if you have trouble sleeping because of anxiety, then it could help calm your anxiety and then help you sleep better or better regulate your sleep cycle. I recommend if you want to try CBD oil, because there’s so much variation from study to study, even on dosing, and a lot of variation from brand to brand that you try it with a doctor who specializes in CBD or marijuana. They should have experience with the dosing from working with patients, and that likely is the best way to try it and also have more experience with different brands and manufacturers. Because anytime you're trying supplements, even if they're natural, there's always a risk of side effects, so that's something to watch out for. Common ones with CBD oil are mood changes, nausea, and diarrhea. Also, it could make you more awake, it could make you more sleepy, it's hard to say because it also depends on your body's absorption and metabolism. So I recommend you work with a doctor who specializes in this, that would be the best way to try it. Personally, I'm not going to try it myself because I don't like taking things if I don't have to, I'm always concerned about potential side effects. So far I've found meditation has helped me the most, so I definitely recommend you try that first. Also, I recommend you try the traditional things like exercising more, cutting caffeine, light therapy, and even the nontraditional things like weighted blankets, etc. before you try something that you have to put in your body, then you have the potential for side effects. Although if you're taking a prescription sleep agent, like Ambien, CBD oil is supposed to have fewer side effects than prescription sleep medications. So that would be a reason to consider switching. But again I recommend you do this with a doctor who specializes in marijuana or CBD to help you with the dose adjustments, which brands are reliable, etc. For more science-backed health and nutrition tips: Follow me on Instagram @healthywithdrmonali Follow me on Twitter @drmonalidesai Subscribe to my YouTube channel Dr. Monali Desai

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What better time to explore new pathways to wellness for yourself or your aging loved one than the New Year? Kensington Senior Living is proud to partner with CV Sciences to present this informative webinar on the why, how and safety of low-dose CBD. Tune in to learn about the bounty of benefits that this treatment option can offer the aging population.  Our panel of experts share the promising results from a recent CBD scientific case series conducted at our Kensington community. Dr. Steven Schmitz of CV Sciences, Registered Nurse Sue Feldmeth of MC Wellness Consulting, Jesse Karagianes of CV Sciences & Kensington Executive Director CC DeGraff speaks firsthand on the incredible impact CBD has had on seniors with dementia, insomnia, anxiety, depression, chronic pain and more.

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